drugset / Trial / NCT02039531
Effect Of Plasma Rich In Growth Factors In Knee Osteoarthritis
Phase 3
Completed
96 enrolled
Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Funds for independent clinical research by the spanish ministry of health · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
HYPOTHESIS: The application of plasma rich in growth factors (PRGF) will improve the quality of life and functional capacity of patients diagnosed with knee osteoarthritis, providing better functional results than conventional treatment with viscosupplementation. OPERATING ASSUMPTIONS Following the initial administration of three doses of PRGF interspersed every 15 days, applied via intraarticular, patients will present an improvement in functional test (WOMAC and Lequesne scales) of 15% or more after 6 and 12 months compared to the control group with patients treated with hyaluronic acid.
Timeline
- Start
- 2011-08
- Primary completion
- 2013-02
- Completion
- 2015-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hyaluronic Acid | Other / unclassified | — | Other |
| Subject | Plasma rich in growth factors | Other / unclassified | — | Other |