drugset / Trial / NCT05562518
GRACE-trial: a Randomized Active-controlled Trial for vulvovaGinal atRophy in breAst Cancer Patients on Endocrine Therapy.
RandomizedParallel-groupSingle-blindTreatment
Summary
In this prospective active-controlled randomized trial the investigators will assess for the first time ever the different local treatments of vulvovaginal atrophy in breast cancer patients on endocrine therapy. These patients are currently inadequately treated based on ignorance of possible treatment modalities and stigmatization of vulvovaginal atrophy.
Timeline
- Start
- 2022-03-21
- Primary completion
- 2026-03-02
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dehydroepiandrosterone | Other / unclassified | — | Other |
| Comparator | Hyaluronic Acid | Other / unclassified | — | Other |
| Comparator | oestriol | Unknown | — | Other |