Hyaluronic Acid-enriched Transfer Medium in Single Blastocyst Transfer

Recruiting 858 enrolled Northwest Women's and Children's Hospital, Xi'an, Shaanxi Gansu Provincial Maternal and Child Health Care Hospital · collab Huazhong University of Science and Technology · collab Jiangxi Maternal and Child Health Hospital · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to compare the live birth rates of high concentration of Hyaluronic Acid (0.5 mg/ml) transfer medium (EmbryoGlue®) to those containing low Hyaluronic Acid concentrations (0.125 mg/ml) (G2 medium) in women undergoing single fresh and frozen blastocyst transfer.

Timeline

Start: 2024-09-13
Primary completion: 2025-12-31
Completion: 2025-12-31

Publications

Cai H, Xu D, Wang Z, Huang B, Xue X, Bai H, Man Y, Lei D, Wu Q, Ni Y, Lei J, Shi J. Efficacy and safety of hyaluronic acid-enriched transfer medium in women undergoing single blastocyst transfer: a study protocol for a multicentre randomised controlled trial. BMJ Open. 2025 Nov 19;15(11):e104571. doi: 10.1136/bmjopen-2025-104571.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Hyaluronic Acid	Other / unclassified	0.125 mg/ml	—
Subject	Hyaluronic Acid	Other / unclassified	0.5 mg/ml	—

Hyaluronic Acid-enriched Transfer Medium in Single Blastocyst Transfer

Summary

Timeline

Publications

Drugs

Indications