To Evaluate the Efficacy and Safety of HUC3-053 in Patients With Dry Eye Syndrome

Summary

This is a multi-center, randomized, double-blinded, non-inferiority study to evaluate the efficacy and safety of HUC3-053 in patients with dry eye syndrome. After a 2-week run-in period, patients will be randomized equally to the HUC3-053 or Hyalein Mini Eye Drops administered bilaterally five to six times a day for 12 weeks.

Timeline

Start

2024-05-20

Primary completion

2025-03-14

Completion

2025-03-21

Publications

• Kim SJ, Kim JY, Kim DH, Lee JS, Kim EC, Shin YJ, Kim HK, Koh JW, Kim TI, Jung D, Choi CY. A Randomized Multicenter Study Comparing Low-Viscosity with Comparator 0.3% Hyaluronic Acid for the Treatment of Dry Eye Disease. Ophthalmol Ther. 2026 Jun;15(6):1927-1939. doi: 10.1007/s40123-026-01372-7. Epub 2026 Apr 17.

Drugs

Indications