drugset / Trial / NCT05291650
Ultrasound-guided Injection of Glucocorticoid Into Infrapatellar Fat Pad in Patients With Knee Osteoarthritis
RandomizedParallel-groupTriple-blindTreatment
Summary
This aims of this study is to investigate the efficacy and safety of the glucocorticoid injection into the infrapatellar fat pad among knee osteoarthritis patients with an inflammatory phenotype.
Timeline
- Start
- 2022-04-25
- Primary completion
- 2023-09-22
- Completion
- 2023-12-26
Publications
- Zhang Y, Ruan G, Fan T, Zheng P, Zhu Z, He J, Wei X, Hu W, Huang S, Chang Q, Gao P, Chen H, Zhou X, Liu X, Tang S, Jiang L, Ding C. Infrapatellar Fat Pad Glucocorticoid Injection in Knee Osteoarthritis: A Randomized Clinical Trial. JAMA Netw Open. 2026 Jan 2;9(1):e2549938. doi: 10.1001/jamanetworkopen.2025.49938.
- Zhang Y, Ruan G, Zheng P, Huang S, Zhou X, Liu X, Hu W, Feng H, Lin Y, He J, Wei Z, Zhang J, Chang Q, Wei X, Fan T, Jiang L, Ding C. Efficacy and safety of GLucocorticoid injections into InfrapaTellar faT pad in patients with knee ostEoarthRitiS: protocol for the GLITTERS randomized controlled trial. Trials. 2023 Jan 3;24(1):6. doi: 10.1186/s13063-022-06993-4.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Betamethasone | Other / unclassified | 1 ml | Other |
| Comparator | Hyaluronic Acid | Other / unclassified | 2.5 ml | Other |
| Comparator | Lidocaine | Other / unclassified | 0.5 ml | Other |