drugset / Trial / NCT05086939
Multicenter Clinical Trial Comparing Treatment with Allogeneic Mesenchymal Cells Versus Autologous Mesenchymal Cells and Versus Active Control with Hyaluronic Acid in Patients with Knee Osteoarthritis.
Phase 3
Active not recruiting
124 enrolled
Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Hospital Universitari de Bellvitge · collabInstitut d'Investigacions Biomèdiques August Pi i Sunyer · collabInstituto de Investigación Biomédica de Salamanca · collabSpanish Clinical Research Network - SCReN · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Phase III, multicenter, randomized, open-label, multicenter clinical trial comparing treatment with allogeneic mesenchymal cells versus autologous mesenchymal cells and versus active control with hyaluronic acid in patients with knee osteoarthritis.
Timeline
- Start
- 2021-05-26
- Primary completion
- 2025-05
- Completion
- 2026-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Allogenic MSCs | Cell therapy | 4e+07 cells | Other |
| Subject | Autologous MSCs | Cell therapy | 4e+07 cells | Other |
| Comparator | Hyaluronic Acid | Other / unclassified | 60 mg | Other |