drugset / Trial / NCT07504250
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy
RandomizedParallel-groupOpen-labelTreatment
Summary
RCT to compare the surgical success in patients undergoing external dacryocystorhinostomy with intraoperative Mitomycin-C (0.4 mg/ml) Vs Hyaluronic acid 1% (1ml) as adjuvant, To compare the complication rates and wound healing patterns in each group, To Compare change in tear MMP-9 levels from preoperative (within 1 week before surgery) to postoperative (6 weeks after surgery) , To compare the comfort levels of patients in each group.
Timeline
- Start
- 2026-04-01
- Primary completion
- 2027-10-30
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hyaluronic Acid | Other / unclassified | 1 % | — |
| Subject | Hyaluronic Acid | Other / unclassified | 1 ml | — |
| Comparator | Mitomycin C | Other / unclassified | 0.4 mg/ml | — |