drugset / Trial / NCT04673643

Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease

NCT04673643

Phase 2 Recruiting 128 enrolled Beijing Tongren Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 256 patients at Beijing Tongren Hospital. Patients completed questionnaires at baseline, 1 month, 3 months, and 6 months.OSDI score, TBUT, Schirmer I, tCFS, MGD score, and psychological status to evaluate the therapeutic effects. A difference of P \< 0.05 was considered statistically significant.

Timeline

Start
2021-07-01
Primary completion
2024-10-01
Completion
2024-10-20

Drugs

EvaluationDrugModalityDoseRoute
Background Hyaluronic Acid Other / unclassified Other

Indications