drugset / Trial / NCT05505214
Topical Steroids & Bacterial Decolonization for Radiation Dermatitis
RandomizedParallel-groupDouble-blindPrevention
Summary
The purpose of this study is to determine whether bacterial decolonization of the nares and skin, topical steroid therapy, or a combination of the two regimens prior to treatment with radiotherapy (RT) for breast and head and neck cancer patients can prevent grade 2 or higher grade radiation dermatitis (RD) graded via the Common Terminology Criteria for Adverse Events (CTCAE) scale and improve quality of life.
Timeline
- Start
- 2023-09-01
- Primary completion
- 2025-09-01
- Completion
- 2025-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine | Small molecule | — | Topical |
| Subject | Mometasone furoate | Other / unclassified | 0.1 % | Topical |
| Subject | Mupirocin | Small molecule | 2 % | Intranasal |