Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery

Unknown 4140 enrolled Seoul National University Hospital

RandomizedParallel-groupSingle-blindPrevention

Summary

This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with vaginal delivery. The primary outcome is the episiotomy site infection.

Timeline

Start: 2021-12
Primary completion: 2025-12-31
Completion: 2026-05-31

Publications

Jung YM, Lee SM, Kim SY, Chung JH, Won HS, Lee KA, Park MH, Cho GJ, Oh MJ, Choi ES, Ahn KH, Hong SC, Sung JH, Roh CR, Kim SM, Kim BJ, Kim HJ, Oh KJ, Hong S, Park IY, Park JS. The Skin Antiseptic agents at Vaginal dElivery (SAVE) trial: study protocol for a randomized controlled trial. Trials. 2023 Feb 21;24(1):130. doi: 10.1186/s13063-023-07101-w.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chlorhexidine	Small molecule	—	Topical
Comparator	Povidone-Iodine	Other / unclassified	—	Topical

Indications

No indication recorded.