Drugs / Povidone-Iodine
last change Jul 2026 re-read 2 minutes ago

Povidone-Iodine

Other / unclassified

Developed for
COVID-19 · dental caries · urinary tract infection · infectious disease · viral conjunctivitis · appendicitis · bacterial conjunctivitis · blepharitis
+36 more · chronic rhinosinusitis · endometritis · methicillin-resistant staphylococcus aureus infectious disease · pleural neoplasm · prosthesis-related infectious disease · Acanthamoeba keratitis · acne · bacterial infectious disease · bacteriuria · common wart · congestive heart failure · corneal ulcer · endophthalmitis · eye infectious disorder · fungal keratitis · gingivitis · neoplasm of esophagus · nosocomial infection · otomycosis · periodontitis · periodontitis, chronic, adult · periprosthetic joint infection · pleural empyema · puerperal infection · respiratory tract infectious disorder · skin infection · staphylococcus aureus infection · thymoma · viral respiratory tract infection · abscess · bacterial urinary tract infection · candidiasis · epidemic keratoconjunctivitis · necrotizing soft tissue infection · pneumothorax · tracheal disorder
Investigated by
3M · University of Miami · Advantage Dental Services, LLC · Advantage Silver Dental Arrest, LLC · Alexandria University · Assiut University
+115 more · Brigham and Women's Hospital · DR. MALA KHAN · IVIEW Therapeutics Inc. · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · McMaster University · National University Hospital, Singapore · Poitiers University Hospital · Research to Prevent Blindness · St. Paul's Hospital, Canada · The University of Texas Health Science Center, Houston · University of California, Los Angeles · University of Iowa · University of Pennsylvania · University of Virginia · University of Washington · Washington University School of Medicine · Yale University · Academic Medical Center - University of Amsterdam · Aga Khan University · Agency for Healthcare Research and Quality (AHRQ) · Altacor Ltd. · Antisepsia Central · Ataturk University · Avrio Health · Bangladesh Reference Institute of Chemical Measurements (BRICM) · Beni-Suef University · Boston Medical Center · Cairo University · Case Western Reserve University · Centers for Disease Control and Prevention · Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Corewell Health East · Dentaid SL · Dhaka Medical College · Emory Healthcare · Emory University · Erasmus Medical Center · Erzincan Military Hospital · FISABIO Foundation · Halodine LLC · Hamilton Health Sciences Corporation · Hasanuddin University · Hisar Intercontinental Hospital · Hitit University · Hospital Clínico Universitario de Valencia · Hospital Universitario Fundación Jiménez Díaz · Hospital Universitario General de Villalba · Hospital Universitario Infanta Elena · Hospital Universitario Virgen de la Arrixaca · Hospital de Clinicas de Porto Alegre · Indiana University · Islamic Science University of Malaysia · Joseph Eye Hospital · King Abdulaziz University · Kolokotrones Family Foundation · L.V. Prasad Eye Institute · Laurentius Hospital Roermond · Leiden University Medical Center · Loma Linda University · Loreen Herwaldt · Ludwig-Maximilians - University of Munich · Mahidol University · Marin L. Schweizer, PhD · Martin-Luther-University Halle-Wittenberg · Mashhad University of Medical Sciences · Meir Medical Center · Menoufia University · Metro Health, Michigan · Military Hospital of Tunis · Mohamed Mousa Mohamed Mousa · Mundipharma Pte Ltd. · NYU Langone Health · Nantes University Hospital · National Cheng-Kung University Hospital · all 121 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) E-Z SCRUB 201 1985-11-29 fda.gov

Trials 94 · started per year

today
US approved 1985
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198519861987198819891990199119921993199419951996199719981999200020012002200320042005200620072008200920102011201220132014201520162017201820192020202120222023202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 05 trials
Phase 0 NCT04457765 Apr 2021 → Sep 2022 Boston Medical Center Withdrawn No outcome recorded
Phase 0 NCT04449965 Jan → Aug 2021 COVID-19 St. Paul's Hospital, Canada Terminated No outcome recorded
Phase 0 NCT04478019 Jul 2020 → Jun 2022 COVID-19 University of Wisconsin, Madison Completed No outcome recorded
Phase 0 NCT02990013 Dec 2018 → Dec 2019 toxic dermatosis University of Miami Completed No outcome recorded
Phase 0 NCT04097613 Jul 2017 → Apr 2019 chronic rhinosinusitis St. Paul's Hospital, Canada Completed No outcome recorded
Phase 15 trials
Phase 1 NCT06339294 Jun → Dec 2023 otomycosis Rawalpindi Medical College Completed No outcome recorded
Phase 1 NCT04761133 Mar → Jul 2021 respiratory tract infectious disorder Alexandria University Completed No outcome recorded
Phase 1 NCT04075526 Oct 2019 → Jan 2024 osteoarthritis NYU Langone Health Completed No outcome recorded
Phase 1 NCT04039126 Jun 2019 → Dec 2020 pleural neoplasm University College Hospital, Ibadan Unknown No outcome recorded
Phase 1 NCT02645617 Mar → Sep 2016 dental caries Advantage Dental Services, LLC Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT04347954 Aug → Dec 2020 COVID-19 Stanford University Completed No outcome recorded
Phase 1/2 NCT04510402 Aug 2020 → Feb 2021 COVID-19, iodine hypothyroidism Brigham and Women's Hospital Unknown No outcome recorded
Phase 1/2 NCT04371458 Jul 2020 → Jul 2025 thymoma Yale University Withdrawn No outcome recorded
Phase 221 trials
Phase 2 NCT06836271 Mar → Apr 2025 overdue prostate cancer Hitit University Not yet recruiting No outcome recorded
Phase 2 NCT05696132 Nov 2024 → Dec 2025 methicillin-resistant staphylococcus aureus infectious disease Nantes University Hospital Terminated No outcome recorded
Phase 2 NCT06616207 Sep 2024 → Mar 2027 expected gingivitis University of Washington Active not recruiting No outcome recorded
Phase 2 NCT03749317 Feb 2023 → Apr 2024 viral conjunctivitis IVIEW Therapeutics Inc. Completed No outcome recorded
Phase 2 NCT05816070 Jan → Nov 2023 bacterial conjunctivitis IVIEW Therapeutics Inc. Completed No outcome recorded
Phase 2 NCT05546762 Sep 2022 → Apr 2024 pleural empyema Alexandria University Completed No outcome recorded
Phase 2 NCT05272254 Sep 2022 → May 2027 expected dental caries University of Rochester Recruiting No outcome recorded
Phase 2 NCT04947527 Jun 2022 → Jun 2024 dental caries Advantage Silver Dental Arrest, LLC Completed No outcome recorded
Phase 2 NCT05239598 Feb → Jul 2022 COVID-19 University of Pennsylvania Completed No outcome recorded
Phase 2 NCT04371965 Sep → Oct 2020 COVID-19 Poitiers University Hospital Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT05895773 Jun → Nov 2023 Menoufia University Completed No outcome recorded
Phase 314 trials
Phase 3 NCT06363877 Jun 2024 → Oct 2026 expected Loma Linda University Recruiting No outcome recorded
Phase 3 NCT06302335 Jan 2023 → Dec 2027 expected Hospital de Clinicas de Porto Alegre Recruiting No outcome recorded
Phase 3 NCT05084378 Mar 2022 → Aug 2024 periprosthetic joint infection Hamilton Health Sciences Corporation Completed No outcome recorded
Phase 3 NCT05021315 Sep 2021 → Sep 2022 infective vaginitis, puerperal infection Cairo University Unknown No outcome recorded
Phase 3 NCT04872686 Apr → May 2021 viral respiratory tract infection DR. MALA KHAN Completed No outcome recorded
Phase 3 NCT04446104 May → Aug 2020 COVID-19 National University Hospital, Singapore Completed No outcome recorded
Phase 3 NCT04048356 Jul 2019 → Feb 2021 female reproductive system disorder, pelvic organ prolapse, urinary tract infection University of New Mexico Completed No outcome recorded
Phase 3 NCT02998554 Mar 2017 → May 2019 viral conjunctivitis Shire Terminated No outcome recorded
Phase 3 NCT01531699 Feb → Oct 2012 infectious disease Altacor Ltd. Completed No outcome recorded
Phase 3 NCT01700803 Jan → Apr 2012 Assiut University Completed No outcome recorded
Phase 427 trials
Phase 4 NCT04200729 Mar 2027 → Mar 2030 expected appendicitis The University of Texas Health Science Center, Houston Not yet recruiting No outcome recorded
Phase 4 NCT07707063 May 2026 → May 2027 expected periodontitis Military Hospital of Tunis Recruiting No outcome recorded
Phase 4 NCT07474194 Sep 2025 → Apr 2026 overdue Beni-Suef University Recruiting No outcome recorded
Phase 4 NCT05745467 Jul 2024 → Jul 2025 COVID-19 University of Iowa Withdrawn No outcome recorded
Phase 4 NCT04941131 May → Jul 2023 COVID-19 King Abdulaziz University Completed No outcome recorded
Phase 4 NCT05763602 Sep 2022 → May 2026 overdue Loreen Herwaldt Active not recruiting No outcome recorded
Phase 4 NCT05529173 Sep 2022 → Nov 2023 methicillin-resistant staphylococcus aureus infectious disease Rutgers, The State University of New Jersey Completed No outcome recorded
Phase 4 NCT05276687 Sep 2022 → Mar 2024 Assiut University Unknown No outcome recorded
Phase 4 NCT05049213 Jun → Aug 2022 COVID-19 National Taiwan University Hospital Completed No outcome recorded
Phase 4 NCT05946005 Dec 2021 → Apr 2022 Hasanuddin University Completed No outcome recorded
Phase not applicable18 trials
NCT07715409 May 2027 expected endometritis Mohamed Mousa Mohamed Mousa Not yet recruiting No outcome recorded
NCT04341688 Dec 2021 → Jun 2022 COVID-19 Aga Khan University Unknown No outcome recorded
NCT07470242 Oct 2021 → Mar 2023 chronic rhinosinusitis Pusan National University Hospital Completed No outcome recorded
NCT05160623 Aug 2021 → Dec 2022 blepharitis Shaare Zedek Medical Center Unknown No outcome recorded
NCT05175027 May → Oct 2021 Hisar Intercontinental Hospital Completed No outcome recorded
NCT06284174 Jan 2021 → Dec 2024 overdue National Cheng-Kung University Hospital Recruiting No outcome recorded
NCT04707742 Jun 2020 → Sep 2021 COVID-19 FISABIO Foundation Completed No outcome recorded
NCT03432975 Dec 2017 → Aug 2019 periodontitis, chronic, adult Cliniques universitaires Saint-Luc- Université Catholique de Louvain Unknown No outcome recorded
NCT02676791 Feb 2016 → Sep 2021 neoplasm of esophagus Technical University Dresden Completed No outcome recorded
NCT02424357 Jul 2015 → Jan 2016 strabismus University of Miami Completed No outcome recorded
Also used as a comparator or background therapy in 70 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT03957291 Comparator Aug 2019 → Aug 2022 Assiut University Unknown No outcome recorded
Phase 0 NCT03571100 Comparator May 2018 → May 2019 age-related macular degeneration, retinal vein occlusion Mid Atlantic Retina Unknown No outcome recorded
Phase 11 trial
Phase 1 NCT04393792 Comparator May 2020 → Mar 2022 COVID-19 Hampshire Hospitals NHS Foundation Trust Unknown No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06906029 Comparator Jul 2026 → Jul 2028 expected abscess University of Alabama at Birmingham Not yet recruiting No outcome recorded
Phase 1/2 NCT04130451 Comparator Oct → Dec 2019 pneumothorax Dow University of Health Sciences Unknown No outcome recorded
Phase 1/2 NCT04041856 Comparator Aug → Oct 2019 epidemic keratoconjunctivitis Farabi Eye Hospital Unknown No outcome recorded
Phase 24 trials
Phase 2 NCT02591251 Comparator Oct 2015 → Mar 2016 Assiut University Completed No outcome recorded
Phase 2 NCT02396329 Comparator Jun 2014 → Jun 2015 Ain Shams Maternity Hospital Unknown No outcome recorded
Phase 2 NCT01577524 Comparator Jan 2012 → Jun 2016 Attabib, Najmedden, M.D. Terminated No outcome recorded
Phase 2 NCT00845819 Comparator Feb 2009 → Oct 2014 chemotherapy-induced oral mucositis Seoul National University Hospital Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03640507 Comparator Oct 2018 → May 2019 Columbia University Completed No outcome recorded
Phase 313 trials
Phase 3 NCT07383402 Comparator Mar 2026 → Dec 2027 expected chronic rhinosinusitis Amin Javer Not yet recruiting No outcome recorded
Phase 3 NCT05127525 Comparator Nov 2021 → Jan 2022 angle-closure glaucoma, diabetic macular edema, occlusion of tributary of retinal vein iRenix Medical, Inc. Terminated No outcome recorded
Phase 3 NCT03925155 Comparator May 2020 → May 2022 Montefiore Medical Center Withdrawn No outcome recorded
Phase 3 NCT03700749 Comparator Nov 2018 → Jul 2021 University of Birmingham Unknown No outcome recorded
Phase 3 NCT03004924 Comparator Mar 2017 → Oct 2018 bacterial conjunctivitis Shire Completed No outcome recorded
Phase 422 trials
Phase 4 NCT07044726 Comparator Jun 2025 → May 2028 expected bacterial urinary tract infection University of Louisville Recruiting No outcome recorded
Phase 4 NCT06705842 Comparator Apr 2025 → Jun 2026 overdue appendicitis The University of Texas Health Science Center, Houston Recruiting No outcome recorded
Phase 4 NCT06744907 Comparator Jan → Nov 2025 overdue Akron Children's Hospital Recruiting No outcome recorded
Phase 4 NCT06282510 Comparator Jan 2024 → Dec 2026 expected candidiasis Mary K Hayden Recruiting No outcome recorded
Phase 4 NCT05919888 Comparator Jun → Nov 2023 periprosthetic joint infection St. Louis University Completed No outcome recorded
Phase not applicable24 trials
NCT07460297 Background Apr 2025 → Jan 2028 expected Jianyi Li Enrolling by invitation No outcome recorded
NCT07295210 Comparator Dec 2024 → Dec 2025 otomycosis Mansoura University Completed No outcome recorded
NCT06400082 Comparator Apr 2023 → Oct 2024 overdue type 2 diabetes mellitus Cairo University Active not recruiting No outcome recorded
NCT06595823 Comparator Mar 2022 → Mar 2023 Egymedicalpedia Completed No outcome recorded
NCT05422703 Background Jan → Jun 2022 temporomandibular joint dysfunction syndrome Cairo University Completed No outcome recorded

Evidence & citations 31 cited values

Every value below carries the sentence it was read from. 171 sources stand behind the page.

FieldValueCited text
Known as Povidone Iodine “The purpose of this study is to see whether applying povidone iodine (PVI) to the noses of patients undergoing lower extremity (leg, ankle, or foot) orthopedic fixation...” NCT05763602
162

“Three antiseptics will be tested: 2% chlorhexidine gluconate in 70% isopropyl alcohol, 10% sodium hypochlorite and 10% povidone-iodine, each one will be applied on the surface...” NCT01321125

“A Phase 2, Multi-center, Randomized, Double-Masked Study to Evaluate the Clinical Efficacy and Safety of IVIEW-1201 (1.0% Povidone-Iodine) Gel Forming Ophthalmic Solution...” NCT03749317

“Participants instructed to instill 1 drop of SHP640 (Povidone-iodine \[PVP-I\] 0.6 percent \[%\] and Dexamethasone 0.1%) ophthalmic suspension in each eye 4 times daily (QID)...” NCT02998554

“In previous studies, povidone iodine (PVP-I), a widely used bactericidal antiseptic, and sodium fluoride (NaF), used to foster remineralization of enamel, were applied...” PMID 30938600 Apr 2018

“In order to assess the effect of Betadine (10% povidone-iodine) in the groin wound on infection rates and recurrence rates in patients undergoing primary varicose vein surgery...” NCT00500669

“MAIN RESULTS: We included 21 trials, reporting results for 7038 women evaluating the effects of vaginal cleansing (17 using povidone-iodine, 3 chlorhexidine, 1 benzalkonium...” PMID 32335895 Apr 2020

“Effect of oropharyngeal povidone-iodine preventive oral care on ventilator-associated pneumonia in severely brain-injured or cerebral hemorrhage patients: a multicenter,...” PMID 24105456 Jan 2014

“Vaginal preparation with povidone-iodine or chlorhexidine solution compared to saline or not cleansing immediately before cesarean delivery probably reduces the risk of...” PMID 30016540 Jul 2018

Povidone iodine (PVP-I) is an alternative decolonization agent solutions and demonstrated rapid and superior bactericidal activity against MRSA in in vitro and ex vivo studies...” NCT05696132

“In this study, we compared the cutaneous antiseptic efficacy of 2% alcoholic chlorhexidine and povidone-iodine-alcohol for preventing the bacterial colonisation of PNCs in...” PMID 33285282 Dec 2020

“Povi-One (10% povidone-iodine) will be applied topically by the graduate student to all tooth surfaces at the consultation appointment (baseline) before the placement of fixed...” NCT06616207

“Although povidone-iodine (iodine) is the only Food and Drug Administration-approved vaginal antiseptic solution, there is a lack of comparative data evaluating alternatives.” PMID 34973179 Dec 2021

“the two-step mouth rinse (0.3% NaOCl followed by 10% Povidone Iodine) decreases the tooth causing germs better than the one-step mouth rinse (10% Povidone Iodine)” NCT03062605

“ChloraPrep (2% chlorhexadine gluconate and 70% isopropyl alcohol) is superior to Betadine (10% povidone iodine) in reducing incision site bacterial colony counts.” NCT01184196

“Drug Name: Povidone-Iodine Dosage form: 0.6% Povidone-Iodine Dosage: 2 puff 0.6% PVP-I in each nostril and 2 puff inside mouth Frequency and duration: Single” NCT04872686

“The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis” NCT06705842

“Povidone-Iodine 5% (PI; brand name: Betadine® 5%; Alcon, Fort Worth, TX), the antiseptic placed on the ocular surface prior to each injection.” NCT05127525

“The effect on viral load was investigated by using 0.5% Povidone-iodine solution as an oral antiseptic for 30 seconds in 25 COVID-19 patients.” NCT05214196

Povidone Iodine 0.5% plus glycyrrhizin acid 2.5 mg/ml as a nasal and an oropharyngeal spray (mint flavored) will be applied 4 times per day.” NCT05895773

“5 % vs. 1.25 % povidone-iodine (PI) as preoperative antiseptic prior to strabismus surgery in children as a prophylaxis of endophthalmitis.” NCT00461656

“About 100 patients women who underwent elective caesarian section with subcutaneous tissue irrigation with Povidone iodine 10% solution.” NCT06595823

“Vigorously rinse with 15 ml of the 1% povidone-iodine (PVP-I) (Betadine Mouthwash/Gargle; Avrio Health LP, Stamford, CT, USA) for 30 s” NCT04721457

“Group A will receive three drops of povidone-iodine ophthalmic solution in each eye, with the right eye to receive the drops first.” NCT03349515

“pyodine Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of wound infection.” NCT04130451

“INTERVENTIONS: One drop of 5% povidone-iodine directly over the sliding noose of the adjustable suture at the end of surgery.” PMID 27561000 Oct 2016

“Name: Repigel Active ingredient: Povidone iodine Dosage form: Liposomal hydrogel Administration route: Topical Strength: 3%” NCT02126709

“Skin preparation with 8.3% povidone-iodine with 72.5% alcohol (Prevail-FX, Cardinal Health) preoperative skin preparation.” NCT01472549

“Povidone-Iodine (PVP-I), common usage in otolaryngology operation and topical therapy, showed high virucidal properties” NCT05049213

Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19” NCT04371965

“Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis” NCT04200729

“Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects” NCT04510402

“Povidone-iodine 2% eye drop versus artificial tear drop for treatment of adenoviral keratoconjunctivitis” NCT04041856

Povidone iodine vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.” NCT04048356

Povidone Iodine 5% (povidone-iodine, Alcon) eye irrigation every day until the patients recovered” NCT04169919

“Povidone-iodine solution 5% w/w (0.5% available iodine) USP Patient Preoperative Skin Preparation” NCT01313182

“The side of the mouth receiving the subgingival irrigations of povidone iodine 10% (test group)” NCT03432975

“Addition of Povidone-Iodine to Fluoride Varnish for Dental Caries: A Randomized Clinical Trial.” PMID 32437626 May 2020

“The choice of antiseptic agent, povidone iodine or chlorhexidine gluconate, remains debated.” PMID 38884982 Aug 2024

“The antiseptic (Povidone-Iodine) is opened, and the surgical site is scrubbed with it.” NCT07474194

“0.2% Povidone-Iodine (Betadiene® by Aviro Health Inc./ Pyodine® by Brooks Pharma Inc.)” PMID 32928313 Sep 2020

“The active ingredients are 10% (w/v) Povidone-Iodine and 5% (w/v) Sodium Fluoride CAS.” NCT04947527

“Povidone-iodine 2% (Betadine© bucal 100 mg/ml) (Mylan Pharmaceuticals, S.L., Spain).” NCT04707742

“Hundred (100) ml of 5% povidone iodine was poured into a sterilized bowl (galipot).” NCT06950229

“Topical 2% Povidone-Iodine Gel (VBP-245) in Subjects With Verruca Vulgaris” NCT04253912

“5 mL of 1% povidone iodine solution delivered using a blunt-tip cannula” NCT07707063

Povidone iodine (PVP-I) nasal irrigation at concentration of 0.4%” NCT04549376

“IVIEW-1201 (1.0% Povidone-Iodine) Gel Forming Ophthalmic Solution” NCT05816070

“The active ingredients are Povidone Iodine and Sodium Fluoride” NCT02645617

“use 0.12% chlorhexidine or povidone iodine mouthwash daily” NCT05422703

“10 mL of Povidone-iodine 0.5% antiseptic mouth rinse” NCT05239598

“chemical sclerosants (ethanol and povidone iodine)” NCT06906029

“Pleural irrigation with 2% povidone iodineNCT05546762

“pleural lavage using 10% povidone-iodine” NCT04371458

Povidone Iodine (P-I) scrub and paint” NCT02202577

povidone iodine and Hypochlorous acid” NCT05175027

“5% povidone iodine (PVI)-69% ethanol” NCT03757143

“SHP640 (povidone-iodine” NCT03004924

NCT03305159

NCT04039126

NCT01919593

NCT03549702

NCT02990013

NCT03700749

NCT01577524

NCT01437228

NCT05946005

NCT01495117

NCT07715409

NCT04347954

NCT05763602

NCT04393792

NCT04210505

NCT00999427

NCT04446104

NCT04603794

NCT01179412

NCT02337972

NCT06339294

NCT07155408

NCT07707063

NCT03348917

NCT04075526

NCT06744907

NCT05160623

NCT00335088

NCT04410159

NCT05077592

NCT02868372

NCT06936475

NCT07460297

NCT01350713

NCT04761133

NCT00231153

NCT02664220

NCT02652325

NCT04169919

NCT05122169

NCT05084378

NCT06284174

NCT02693483

NCT04745663

NCT05272254

NCT02527512

NCT05021315

NCT00290290

NCT00516399

NCT02396329

NCT02027324

NCT04478019

NCT03014778

NCT02713074

NCT07470242

NCT07295210

NCT05529173

NCT05546762

NCT01619137

NCT03447639

NCT05745467

NCT06363877

NCT06616207

NCT04457765

NCT04364802

NCT03484507

NCT03118232

NCT00845819

NCT04146116

NCT04449965

NCT01700803

NCT00896402

NCT03133312

NCT02391714

NCT04941131

NCT00386958

NCT03957291

NCT01481519

NCT05919888

NCT03560193

NCT00692484

NCT07383402

NCT01216761

NCT06282510

NCT04097613

NCT01893060

NCT02245334

NCT06302335

NCT07044726

NCT02975921

NCT01898728

NCT02032394

NCT06400082

NCT02676791

NCT03385304

NCT04371965

NCT03101371

NCT02479347

NCT01560962

NCT00950027

NCT02202577

NCT01886001

NCT02591251

NCT04278950

NCT04517188

Known as Betadiene “0.2% Povidone-Iodine (Betadiene® by Aviro Health Inc./ Pyodine® by Brooks Pharma Inc.)” PMID 32928313 Sep 2020
Known as Betadine “250 ml solution of 2% povidone-iodine (i.e. 50 ml betadine in 200 ml saline) will be attached to the chest tube via a giving set and a 3-way tap and irrigated into the pleural...” NCT05546762
14

“with sterile water (water that has been treated to remove bacteria and living organisms) vs Betadine also known as Povidone-Iodine (a medical grade cleaning solution)” NCT07044726

“ChloraPrep (2% chlorhexadine gluconate and 70% isopropyl alcohol) is superior to Betadine (10% povidone iodine) in reducing incision site bacterial colony counts.” NCT01184196

“Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure” NCT03549702

“Treatment A = Betadine® 7.5% skin cleanser (PVP-I 7.5%)” NCT03348917

“0.2% Povidone-Iodine (BETADINE®) 10 ml gargle” NCT04341688

“0.35% povidone-iodine ("Betadine")” NCT02527512

“topical betadine (Povidone-iodine)” PMID 28549873 May 2017

NCT05276687

NCT04981860

NCT01531699

NCT02116608

NCT03173053

NCT00500669

NCT02472223

Known as Betadine 5% “Povidone-Iodine 5% (PI; brand name: Betadine® 5%; Alcon, Fort Worth, TX), the antiseptic placed on the ocular surface prior to each injection.” NCT05127525
Known as Betadine bucal 100 mg/ml “Povidone-iodine 2% (Betadine© bucal 100 mg/ml) (Mylan Pharmaceuticals, S.L., Spain).” NCT04707742
Known as Betadine7.5% “The patients will be subjected to povidone-iodine (Betadine7.5%, Phama Care) for vaginal cleaning before the laparoscopic surgery” NCT02591251
1

“The patients will be subjected to povidone-iodine (Betadine7.5%) for vaginal cleaning before office hysteroscopy” NCT02713074

Known as Bétadine alcoolique “Groupe A: (1) 5% (w/v) PVI-69% (v/v) ethanol (Bétadine alcoolique™, MEDA Pharma SAS); (2) InsyteTM AutoguardTM BC Winged, BD” NCT03757143
Known as iodine “Although povidone-iodine (iodine) is the only Food and Drug Administration-approved vaginal antiseptic solution, there is a lack of comparative data evaluating alternatives.” PMID 34973179 Dec 2021
Known as Isodine Solucion “The arm is composed of 10 human volunteers to test 2% chlorhexidine gluconate in 70% isopropyl alcohol (ChloraPrep ®, Enturia, Texas, USA ), hypochlorite 10% of electrochemical...” NCT01321125
Known as IVIEW-1201 “A Phase 2, Multi-center, Randomized, Double-Masked Study to Evaluate the Clinical Efficacy and Safety of IVIEW-1201 (1.0% Povidone-Iodine) Gel Forming Ophthalmic Solution...” NCT03749317
1

IVIEW-1201 (1.0% Povidone-Iodine) Gel Forming Ophthalmic Solution” NCT05816070

Known as Nasal Povidone Iodine ClinicalTrials.gov intervention name — accepted as the source's own label NCT02216227
Known as P-I “Povidone Iodine (P-I) scrub and paint” NCT02202577
Known as Polividon- iyot “%10 Polivinilpirolidon iyot (Polividon- iyotNCT01437228
Known as Polivinilpirolidon iyot “%10 Polivinilpirolidon iyot (Polividon- iyot” NCT01437228
Known as Polyvinylpyrrolidone-Iodine “a polyvinylpyrrolidone-iodine (PVP-I; povidone-iodine) and NaF topical varnish was superior to one containing only NaF in prevention of new dental caries lesions” PMID 32437626 May 2020
1

“efficacy of topical 10% Polyvinylpyrrolidone-Iodine (PVPI) to prevent new caries lesions” NCT05272254

Known as Povi-One Povi-One (10% povidone-iodine) will be applied topically by the graduate student to all tooth surfaces at the consultation appointment (baseline) before the placement of fixed...” NCT06616207
Known as Povidine iodine “with PI (povidine iodine) and AC (aqueous chlorhexidine).” NCT03957291
3

NCT03571100

NCT03640507

NCT06836271

Known as povidon iodine “Drug: povidon iodineNCT02950246
Known as Povidone iodide “Betadine (Povidone iodide) for reducing bacteria and patient discomfort in the eyes.” NCT04981860
Known as Povidone-iodine 0.5% (Betadine) (PVP-I) Povidone-iodine 0.5% (Betadine) (PVP-I)NCT05214196
Known as Povidone-Iodine, USP 10% topical solution Povidone-Iodine, USP 10% topical solutionNCT00896402
Known as PROFEND “This study aims to evaluate the real-world effectiveness of nasal povidone-iodine (PROFEND®) in a group of 50 patients at the University of Iowa.” NCT04146116
Known as PVI “The purpose of this study is to see whether applying povidone iodine (PVI) to the noses of patients undergoing lower extremity (leg, ankle, or foot) orthopedic fixation...” NCT05763602
6

“superiority of chlorhexidine (CHG)-alcohol over povidone iodine (PVI)-alcohol, the two most common alcohol-based antiseptic solutions used worldwide, is controversial.” PMID 31213447 Jun 2019

“Povidone-iodine (PVI) is an antiseptic solution consisting of polyvinylpyrrolidone with water, iodide, and 1% available iodine.” NCT02664220

“Povidone-iodine (PVI) is a widely used antimicrobial agent.” NCT05160623

“intra-abdominal irrigation with povidone-iodine (PVI)” NCT04200729

“5% povidone iodine (PVI)-69% ethanol” NCT03757143

“povidone-iodine (PVI) irrigation” NCT06705842

Known as PVP-I “Participants instructed to instill 1 drop of SHP640 (Povidone-iodine \[PVP-I\] 0.6 percent \[%\] and Dexamethasone 0.1%) ophthalmic suspension in each eye 4 times daily (QID)...” NCT02998554
13

“In previous studies, povidone iodine (PVP-I), a widely used bactericidal antiseptic, and sodium fluoride (NaF), used to foster remineralization of enamel, were applied...” PMID 30938600 Apr 2018

“Povidone iodine (PVP-I) is an alternative decolonization agent solutions and demonstrated rapid and superior bactericidal activity against MRSA in in vitro and ex vivo studies...” NCT05696132

“1.25% Povidone-Iodine (PVP-I) (also known as betadine) to be used pre-procedure in the operating room via irrigation into the nasal cavity to act as viricidal preparation for...” NCT04457765

“Povidone-iodine (PVP-I) has broad antimicrobial and anti-inflammatory properties, while budesonide is a corticosteroid commonly used intranasally to reduce sinonasal inflammation.” NCT07383402

“a polyvinylpyrrolidone-iodine (PVP-I; povidone-iodine) and NaF topical varnish was superior to one containing only NaF in prevention of new dental caries lesions” PMID 32437626 May 2020

“Vigorously rinse with 15 ml of the 1% povidone-iodine (PVP-I) (Betadine Mouthwash/Gargle; Avrio Health LP, Stamford, CT, USA) for 30 s” NCT04721457

“Povidone-Iodine (PVP-I), common usage in otolaryngology operation and topical therapy, showed high virucidal properties” NCT05049213

“Povidone-iodine (PVP-I) is a broad-spectrum antiseptic with activity against bacteria, fungi, and viruses.” NCT04364802

“Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects” NCT04510402

“efficacy of topical 10% Polyvinylpyrrolidone-Iodine (PVPI) to prevent new caries lesions” NCT05272254

“Povidone iodine (PVP-I) nasal irrigation at concentration of 0.4%” NCT04549376

“7.5% Povidone-Iodine [PVP-I]” NCT03348917

“povidone-iodine (PVP-I)” NCT06302335

Known as PVP-Iodine “SHP640 (PVP-Iodine 0.6% and Dexamethasone 0.1%) Ophthalmic Suspension” NCT03004924
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NCT01647347