drugset / Trial / NCT04449965

Povidone-Iodine Rinses in the Management of COVID-19

NCT04449965

Phase 0 Terminated 5 enrolled St. Paul's Hospital, Canada
RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of this study is to determine if Povidone iodine (PVP-I) rinses and throat gargles or a PVP-I gel forming nasal spray compared to a placebo (a treatment that has no physical effect to a person) is an effective treatment for patients diagnosed with COVID-19. These patients have been diagnosed with mild/moderate COVID-19 symptoms and sent home for self-isolation. Patients will be instructed to take either of the two treatments or placebo twice daily for two weeks and have follow up visits 2 and 4 weeks after. The participants will also complete study related procedures such as saliva sample collection, and two questionnaires throughout the study period. The investigators hypothesize that COVID 19 positive participants who use either of the Povidone - Iodine treatment will have a reduction in their viral load, develop a negative oral mucosa sample and improve their clinical symptoms.

Timeline

Start
2021-01-19
Primary completion
2021-08-16
Completion
2021-08-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Povidone-Iodine Other / unclassified 0.23 % Other
Subject Povidone-Iodine Other / unclassified 0.6 % Other

Indications