Chlorohexidine Versus Povidone Iodine as Apreoperative Ophthalmic Disinfectant

Phase 0 Unknown 100 enrolled Assiut University

RandomizedParallel-groupSingle-blindPrevention

Summary

1. Is to assess the efficacy of preoperative disinfection with chlorohexidine and povidone iodine in different concentrations separately . 2. Is to compare the efficacy of chlorohexidine to povidone iodine. 3. Compare patient comfort after instillation of each disinfectant . 4. To find which disinfectant is more effective tolerated and more safe for use .

Timeline

Start: 2019-08
Primary completion: 2022-08
Completion: 2022-12

Publications

Background Grzybowski A, Kanclerz P, Myers WG. The use of povidone-iodine in ophthalmology. Curr Opin Ophthalmol. 2018 Jan;29(1):19-32. doi: 10.1097/ICU.0000000000000437.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Chlorhexidine	Small molecule	0.05 %	Topical
Comparator	Chlorhexidine	Small molecule	0.1 %	Topical
Comparator	Povidone-Iodine	Other / unclassified	2.5 %	Topical
Comparator	Povidone-Iodine	Other / unclassified	5 %	Topical

Indications

No indication recorded.