drugset / Trial / NCT04745663
Optimizing Preoperative Disinfection of Eyes
Phase 4
Terminated
150 enrolled
Norwegian University of Science and Technology
St. Olavs Hospital · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
Topical povidone-iodine (PI) is widely used as ocular antiseptic before and after surgery. The standard dose of 5% PI is however, associated with ocular irritation. We therefore want to test if a lower concentration of PI can be similarly efficacious in reducing bacterial growth while reducing ocular irritation.
Timeline
- Start
- 2021-02-08
- Primary completion
- 2021-04-30
- Completion
- 2021-04-30
Outcome
Outcome not reported
Stopped: “Not the expected 2/3 but only 1/3 of conjunctiva samples got bacterial growth. Lack of resources to keep the study going with more participants and over a considerably longer time than anticipated.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Povidone-Iodine | Other / unclassified | 0.3 % | Other |
| Subject | Povidone-Iodine | Other / unclassified | 5 % | Other |