drugset

drugset / Trial / NCT03685604

PVP Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site

NCT03685604 ↗

Phase 4 Completed 3321 enrolled University Hospital, Basel, Switzerland Swiss National Science Foundation · collab

RandomizedParallel-groupSingle-blindDiagnostic

Summary

Prospective cluster-randomized multicenter cross-over trial to prove non-inferiority of PI compared to CHX in preoperative skin antisepsis

Timeline

Start: 2018-09-10
Primary completion: 2020-06-30
Completion: 2020-06-30

Publications

Widmer AF, Atkinson A, Kuster SP, Wolfensberger A, Klimke S, Sommerstein R, Eckstein FS, Schoenhoff F, Beldi G, Gutschow CA, Marschall J, Schweiger A, Jent P. Povidone Iodine vs Chlorhexidine Gluconate in Alcohol for Preoperative Skin Antisepsis: A Randomized Clinical Trial. JAMA. 2024 Aug 20;332(7):541-549. doi: 10.1001/jama.2024.8531.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Chlorhexidine gluconate	Other / unclassified	2 %	Topical
Comparator	Povidone-Iodine	Other / unclassified	—	Topical

Indications

No indication recorded.