Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.

Recruiting 105 enrolled National Cheng-Kung University Hospital

RandomizedParallel-groupDouble-blindPrevention

Summary

This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is more effective. Additionally, we aim to evaluate any side effects associated with the use of these two antiseptic solutions for wound irrigation.

Timeline

Start: 2021-01-01
Primary completion: 2024-12-31
Completion: 2025-05-31

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chlorhexidine gluconate	Other / unclassified	0.05 %	Other
Subject	Povidone-Iodine	Other / unclassified	3.5 %	Other

Indications

No indication recorded.