drugset / Trial / NCT02572791
Staph Household Intervention for Eradication (SHINE)
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators propose a pragmatic comparative effectiveness trial evaluating several decolonization strategies in patients with Staphylococcus aureus infection, their household contacts, and household environmental surfaces. The central hypothesis of this proposal is that an integrated approach of periodic personal and household environmental hygiene will reduce S. aureus transmission in households and subsequently decrease the incidence of skin and soft tissue infections (SSTI).
Timeline
- Start
- 2015-10
- Primary completion
- 2024-11
- Completion
- 2024-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine | Small molecule | — | Topical |
| Subject | Mupirocin | Small molecule | — | Topical |