drugset / Trial / NCT02572791

Staph Household Intervention for Eradication (SHINE)

NCT02572791

Phase 4 Completed 835 enrolled Washington University School of Medicine
RandomizedParallel-groupOpen-labelTreatment

Summary

The investigators propose a pragmatic comparative effectiveness trial evaluating several decolonization strategies in patients with Staphylococcus aureus infection, their household contacts, and household environmental surfaces. The central hypothesis of this proposal is that an integrated approach of periodic personal and household environmental hygiene will reduce S. aureus transmission in households and subsequently decrease the incidence of skin and soft tissue infections (SSTI).

Timeline

Start
2015-10
Primary completion
2024-11
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine Small molecule Topical
Subject Mupirocin Small molecule Topical