drugset / Trial / NCT07824388
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
RandomizedCrossoverTriple-blindTreatment
Summary
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash). Following a baseline oral health assessment, participants will use the assigned mouthwash twice daily for 4 consecutive days while refraining from all mechanical oral hygiene practices (e.g., tooth brushing). The trial follows a 2-phase crossover design, where participants use one mouthwash in the first phase and the other in the second phase, separated by a 15-day washout period.
Timeline
- Start
- 2026-03-02
- Primary completion
- 2026-07-10
- Completion
- 2026-07-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bioflavonoid mouthwash | Unknown | — | Topical |
| Subject | Chlorhexidine | Small molecule | — | Topical |