drugset / Trial / NCT04453124
An Accessible Low-cost Plant Treatment for Cutaneous Ulcers
Phase 2
Completed
150 enrolled
Oriol Mitja
The Royal Botanic Gardens, Kew · collabThe University of Papua New Guinea · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
In a search for accessible treatment options, plant medicines used by different communities in Papua New Guinea have been tested to identify the sap of the tree, Ficus septica, as a promising antibacterial agent in vitro. This is an open label clinical trial using an interventional approach, to compare the effect of the antiseptic plant sap and standard topical antiseptic, on the rate of wound development prevention and bacterial growth. If shown to be effective, this readily available plant medicine can provide a zero-cost treatment option in remote areas of PNG.
Timeline
- Start
- 2019-11-01
- Primary completion
- 2019-11-22
- Completion
- 2019-11-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine | Small molecule | 0.05 ml | Topical |
| Subject | Ficus Septica Sap | Unknown | 0.05 ml | Topical |