Efficacy of Injectable Gentamicin in Hereditary Ichthyosis

Summary

This study will evaluate the efficacy and safety of intravenous gentamicin in congenital ichthyosis due to a non-sens mutation. The primary objective is the severity of scales and erythema at the third month, compared to baseline. Secondary objectives will include: the importance of itching, trans epidermal water loss, cutaneous expression of the targeted protein, the security of the drug and patients' satisfaction.

Timeline

Start

2024-09

Primary completion

2026-04-01

Completion

2027-04-01

Drugs

Indications