Effect of Gentamicin Lavage of the Axillary Surgical Bed After Lymph Node Dissection on Drainage Discharge Volume

Phase 3 Completed 40 enrolled Hospital General Universitario Elche

RandomizedParallel-groupTriple-blindPrevention

Summary

The effect of axillary lavage with a gentamicin solution before wound closure will reduce the drainage volume and subsequently day of drainage removal.

Timeline

Start: 2011-05
Primary completion: 2012-09
Completion: 2012-09

Outcome

Met primary endpoint

paper Total drainage volume before removal was 465 ± 250.9 ml in Group 1 and 169 ± 102.2 ml in Group 2 (p = 0.003). PMID 23602424 ↗

Publications

Ruiz-Tovar J, Cansado P, Perez-Soler M, Gomez MA, Llavero C, Calero P, Zubiaga L, Diez M, Arroyo A, Calpena R. Effect of gentamicin lavage of the axillary surgical bed after lymph node dissection on drainage discharge volume. Breast. 2013 Oct;22(5):874-8. doi: 10.1016/j.breast.2013.03.008. Epub 2013 Apr 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gentamicin	Small molecule	240 mg	Other

Indications

No indication recorded.