Antenatal Rescue Course of Glucocorticoids in Threatened Premature Birth

Summary

Administration of steroid to the mother in imminent preterm delivery is a known effective practice to decrease the risk of respiratory distress syndrome and intraventricular haemorrhage in preterm infants if given with a week of the preterm delivery. This randomized clinical trial is performed to test the possibility whether the repeat dose of steroid results in further reduction of these diseases in case the mother is in imminent preterm delivery more than a week after the first antenatal steroid treatment.

Timeline

Start

2001-05

Primary completion

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Completion

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Publications

• Pesonen AK, Raikkonen K, Lano A, Peltoniemi O, Hallman M, Kari MA. Antenatal betamethasone and fetal growth in prematurely born children: implications for temperament traits at the age of 2 years. Pediatrics. 2009 Jan;123(1):e31-7. doi: 10.1542/peds.2008-1809. Epub 2008 Dec 15.

Drugs

Indications