drugset / Trial / NCT00297128
Preoperative Chemoradiation With Capecitabine and Cetuximab
Phase 2
Completed
31 enrolled
Austrian Breast & Colorectal Cancer Study Group
Hoffmann-La Roche · collabMerck Gesellschaft mbH, Austria · collab
NaSingle-groupOpen-labelTreatment
Summary
* feasibility and tolerance of preoperative therapy with Cetuximab in combination with Capecitabine and radiotherapy for patients with locally advanced operable rectal carcinoma * collection of response rate (T-downstaging, pathological complete remission), correlation of responsiveness with EGFR-status
Timeline
- Start
- 2005-10
- Primary completion
- 2011-08
- Completion
- 2011-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Capecitabine | Small molecule | 825 mg/m2 | — |
| Comparator | Cetuximab | Monoclonal antibody | 250 mg/m2 | — |