Assessment of Tramadol as a Treatment for Opioid Addiction

Phase 1/2 Completed 9 enrolled Johns Hopkins University National Institute on Drug Abuse (NIDA) · collab

RandomizedCrossoverTriple-blindTreatment

Summary

Opioids are one of the most commonly abused drugs among individuals who seek treatment for drug abuse. Thus, it is necessary to develop new treatments for opioid addiction. The purpose of this trial is determine whether tramadol is effective in treating opioid dependent individuals.

Timeline

Start: 2006-01
Primary completion: 2007-10
Completion: 2007-11

Publications

Results Lanier RK, Lofwall MR, Mintzer MZ, Bigelow GE, Strain EC. Physical dependence potential of daily tramadol dosing in humans. Psychopharmacology (Berl). 2010 Sep;211(4):457-66. doi: 10.1007/s00213-010-1919-3. Epub 2010 Jun 30.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tramadol	Other / unclassified	200 mg	Oral
Subject	Tramadol	Other / unclassified	800 mg	Oral

Assessment of Tramadol as a Treatment for Opioid Addiction

Summary

Timeline

Publications

Drugs

Indications