drugset / Trial / NCT00309179

A Phase II Study of the Safety and Efficacy of E7820 Plus Cetuximab in Colorectal Cancer, Preceded by a Run-in Study in Advanced Solid Tumors

NCT00309179

Phase 2 Completed 41 enrolled Eisai Inc.
NaSingle-groupOpen-labelTreatment

Summary

This study proposes to determine the safety of the administration of E7820 plus cetuximab and explore the MTD of the combination in a Phase Ib study. In addition, the efficacy of this combination will be explored in patients with colorectal cancer in the Phase II proof of concept phase of the study.

Timeline

Start
2007-09-24
Primary completion
2009-12-14
Completion
2017-02-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody
Subject E7820 Small molecule
Subject Irinotecan Small molecule 40 mg/m2

Indications