drugset / Trial / NCT00309569
Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
Primarily, this clinical investigation compared overall survival and recurrence-free survival in patients with hormone receptor-negative breast cancer treated with pre- and postoperative chemotherapy vs. conventional postoperative treatment.
Timeline
- Start
- 1991-10
- Primary completion
- 2000-09
- Completion
- 2000-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 600 mg/m2 | — |
| Subject | Epirubicin | Small molecule | 60 mg/m2 | — |
| Subject | Methotrexate | Small molecule | 40 mg/m2 | — |
| Subject | fluorouracil | Small molecule | 600 mg/m2 | — |