drugset / Trial / NCT00311311
Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether immunosuppression by tacrolimus, mycophenolate mofetil, and prednisone compared to conversion to sirolimus, mycophenolate mofetil, and prednisone affect the progression of atherosclerosis in renal transplant recipients.
Timeline
- Start
- 2006-04
- Primary completion
- 2010-12
- Completion
- 2012-01
Outcome
Outcome not reported
Stopped: “See termination reason in detailed description.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sirolimus | Small molecule | 3 mg | — |
| Subject | Tacrolimus | Small molecule | — | — |
| Background | Mycophenolate Mofetil | Small molecule | 500 mg | Oral |
| Background | Prednisone | Other / unclassified | 2.5 mg | Oral |