Tranexamic Acid in HIp Fracture Surgery (THIF Study)

Phase 3 Completed 110 enrolled University Hospital of Saint-Etienne

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to assess the efficacy of tranexamic acid in hip fracture surgery on the reduction of allogeneic red blood cell transfusion.

Timeline

Start: 2005-04
Primary completion: 2007-02
Completion: 2007-02

Publications

Zufferey PJ, Miquet M, Quenet S, Martin P, Adam P, Albaladejo P, Mismetti P, Molliex S; tranexamic acid in hip-fracture surgery (THIF) study. Tranexamic acid in hip fracture surgery: a randomized controlled trial. Br J Anaesth. 2010 Jan;104(1):23-30. doi: 10.1093/bja/aep314.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Tranexamic Acid	Small molecule	15 mg/kg	Intravenous

Indications

No indication recorded.