Drugs / Tranexamic Acid
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Tranexamic Acid

also known as TXA · Cyklokapron · EXACYL · Kapron · Capron · LB1148 · Transamin · Cyclokapron · +25 more

Small molecule

Developed for
hemorrhagic disease · osteoarthritis, knee · hyperpigmentation of the skin · anemia · menstrual disorder · rotator cuff syndrome · bone disorder · osteoarthritis
+121 more · osteoarthritis, hip · arthropathy · bleeding disorder, vascular-type · coronary artery disorder · leiomyoma · traumatic brain injury · uterine disorder · benign prostatic hyperplasia · chronic rhinosinusitis · COVID-19 · craniosynostosis · hematopoietic and lymphoid cell neoplasm · ileus · placenta praevia · venous thromboembolism · blood coagulation disease · intracerebral hemorrhage · nephrolithiasis · pregnancy disorder · prostate cancer · scoliosis · acquired coagulation factor deficiency · active peptic ulcer disease · cardiac valvular defect · cirrhosis of liver · eyelid disorder · fibrinolytic defect · head and neck neoplasm · hemophilia · hereditary hemorrhagic telangiectasia · infectious disease with sepsis · inflammatory disease · lower respiratory tract disorder · lumbar spinal stenosis · meningioma · ovarian cancer · pelvic organ prolapse · shoulder impingement syndrome · tonsillitis · urinary bladder cancer · uterine corpus leiomyoma · vascular hemostatic disease · von Willebrand disease (hereditary or acquired) · abdominal aortic aneurysm · acute myeloid leukemia · adolescent idiopathic scoliosis · aortic disorder · arteriovenous hemangioma/malformation · chronic liver failure · chronic pain syndrome · colon carcinoma · conjunctival disorder · developmental dysplasia of the hip · disease of orbital part of eye adnexa · endometrial disorder · Ewing sarcoma of bone · female breast carcinoma · female reproductive system neoplasm · gastric cancer · gastric neoplasm · hemarthrosis · hemophilia A · hepatocellular carcinoma · hyperpigmentation of eyelid · hypotensive disorder · lichen planus pigmentosus · lung disorder · lymphedema · lymphocele · malignant pancreatic neoplasm · melanoma · meningitis · metastatic malignant neoplasm in the spinal cord · myelodysplastic syndrome · myelodysplastic/myeloproliferative neoplasm · neoplasm of esophagus · obstetric disorder · osteogenesis imperfecta · osteoporosis · osteosarcoma · palmar fibromatosis · perianal hematoma · phlebectasia of lips · placenta accreta · placental abruption · platelet disorder, undefined · pneumonia · polyp of large intestine · skin disorder · skin squamous cell carcinoma · spinal stenosis · stomach polyp · thrombocytopenia · tumor of duodenum · upper digestive tract disorder · urethral stricture · urinary tract obstruction · varicose disease · vertebral column disorder · adenoid hypertrophy · alveolar periostitis · angiodysplasia of intestine · bronchial disorder · chronic urticaria · colorectal cancer · congenital heart disease · epilepsy · esophageal varices with bleeding · hereditary angioedema · intervertebral disk degenerative disorder · musculoskeletal system cancer · nosocomial infection · obesity disorder · skin infection · skin pigmentation disorder · soft tissue sarcoma · spinal cord disorder · spinal cord injury · subarachnoid hemorrhage · toe, misshapen · uterine anomalies
Investigated by
Cairo University · Assiut University · London School of Hygiene and Tropical Medicine · Aswan University Hospital · Chinese Academy of Medical Sciences, Fuwai Hospital · NYU Langone Health
+509 more · National Cheng-Kung University Hospital · Northwestern University · University Health Network, Toronto · Ferring Pharmaceuticals · St. Olavs Hospital · University of Alabama at Birmingham · Indonesia University · Konkuk University Medical Center · Sant Pau Research Institute · Sunnybrook Health Sciences Centre · Al-Azhar University · Assaf-Harofeh Medical Center · Bayer · Campbell Clinic · Canadian Institutes of Health Research (CIHR) · Clinical Hospital Centre Zagreb · Corewell Health West · George Washington University · Hamilton Health Sciences Corporation · Henry Ford Health System · Hospital for Special Surgery, New York · McMaster University · Ministry of Health, France · Montefiore Medical Center · National Heart, Lung, and Blood Institute (NHLBI) · Ottawa Hospital Research Institute · Pfizer · RenJi Hospital · Rush University Medical Center · Tanta University · Thammasat University · University of California, San Francisco · University of Wisconsin, Madison · Washington University School of Medicine · Yonsei University · Albany Medical College · Asan Medical Center · Azienda U.S.L. 1 di Massa e Carrara · Benha University · Boston Children's Hospital · Dalhousie University · Daniel Nishijima, MD, MAS · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · First Affiliated Hospital, Sun Yat-Sen University · HaEmek Medical Center, Israel · Haseki Training and Research Hospital · Hebei Medical University Third Hospital · Hua Luo · King Edward Medical University · Korea Health Industry Development Institute · M.D. Anderson Cancer Center · Massachusetts General Hospital · Meir Medical Center · Monash University · Mount Sinai Hospital, Canada · Nanfang Hospital, Southern Medical University · National Health and Medical Research Council, Australia · Oregon Health and Science University · Palisade Bio · Pediatric Emergency Care Applied Research Network · Population Health Research Institute · Rabin Medical Center · Rawalpindi Medical College · Second Affiliated Hospital of Guangzhou Medical University · Second Affiliated Hospital, School of Medicine, Zhejiang University · Seoul National University Hospital · Shanghai Jiao Tong University School of Medicine · Stanford University · Taipei Veterans General Hospital, Taiwan · The First Affiliated Hospital of Zhengzhou University · The Hospital for Sick Children · The Physicians' Services Incorporated Foundation · The University of Texas Health Science Center at San Antonio · The University of Texas Health Science Center, Houston · all 515 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) CYKLOKAPRON 1986-12-30 fda.gov

Trials 446 · started per year

today
US approved 1986
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 018 trials
Phase 0 NCT07565753 Jul 2026 → Sep 2027 expected bleeding disorder, vascular-type, tonsillitis The University of Texas Health Science Center at San Antonio Recruiting No outcome recorded
Phase 0 NCT07362992 Jul 2026 → Dec 2028 expected Wolfson Medical Center Recruiting No outcome recorded
Phase 0 NCT06580509 Feb 2026 → Sep 2027 expected bleeding disorder, vascular-type, tonsillitis The University of Texas Health Science Center at San Antonio Recruiting No outcome recorded
Phase 0 NCT06725732 Jan → Dec 2025 overdue Assiut University Recruiting No outcome recorded
Phase 0 NCT06345833 Jul 2024 → Jul 2026 overdue hemophilia, hemorrhagic disease University of Minnesota Recruiting No outcome recorded
Phase 0 NCT06097611 Nov 2023 → Nov 2024 Assiut University Unknown No outcome recorded
Phase 0 NCT04630886 Jun 2021 → Jan 2024 skin neoplasm Riley McLean Terminated No outcome recorded
Phase 0 NCT04797156 Mar 2021 → Aug 2024 Icahn School of Medicine at Mount Sinai Completed No outcome recorded
Phase 0 NCT04541303 Oct 2020 → Dec 2021 University of Missouri-Columbia Completed No outcome recorded
Phase 0 NCT04488367 Jul 2020 → Jul 2023 bone disorder Community Memorial Health System Unknown No outcome recorded
Phase 16 trials
Phase 1 NCT05774717 Apr 2023 → Apr 2029 expected Vanderbilt University Medical Center Recruiting No outcome recorded
Phase 1 NCT03777488 Oct 2019 → Oct 2020 London School of Hygiene and Tropical Medicine Completed No outcome recorded
Phase 1 NCT04100447 Nov 2018 → Mar 2020 ileus Ronald Hurst, MD, FACS Completed No outcome recorded
Phase 1 NCT02561923 Aug 2015 → Jun 2016 Janssen Scientific Affairs, LLC Completed No outcome recorded
Phase 1 NCT02620748 Mar 2015 → Feb 2018 leiomyoma George Washington University Completed No outcome recorded
Phase 1 NCT01683955 Jan → Nov 2013 anemia, osteoarthritis, hip Henry Ford Health System Completed No outcome recorded
Phase 1/210 trials
Phase 1/2 NCT06983886 May 2025 → Jun 2026 overdue Ramathibodi Hospital Not yet recruiting No outcome recorded
Phase 1/2 NCT06997796 May → Dec 2025 overdue Dr. Anne Conlin Recruiting No outcome recorded
Phase 1/2 NCT06023212 Dec 2023 → Jan 2026 overdue metastatic malignant neoplasm in the spinal cord Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting No outcome recorded
Phase 1/2 NCT04555343 Mar → Sep 2021 prostate cancer, urinary bladder cancer, urinary tract obstruction Fraser Health Completed No outcome recorded
Phase 1/2 NCT03875937 Sep 2019 → Feb 2020 London School of Hygiene and Tropical Medicine Completed No outcome recorded
Phase 1/2 NCT03806556 Apr 2019 → Aug 2020 acquired coagulation factor deficiency, childhood malignant neoplasm, hemorrhagic disease, thrombocytopenia Meghan McCormick Terminated No outcome recorded
Phase 1/2 NCT02604719 Nov 2015 → May 2016 Ahmed Alanwar Unknown No outcome recorded
Phase 1/2 NCT02688127 Aug 2015 → Feb 2016 pregnancy disorder Medical Research Council Completed No outcome recorded
Phase 1/2 NCT02350179 Jun 2014 → Apr 2015 perianal hematoma Ain Shams University Unknown No outcome recorded
Phase 1/2 NCT01085006 Sep 2009 → Aug 2010 hemorrhagic disease Tehran University of Medical Sciences Completed No outcome recorded
Phase 245 trials
Phase 2 NCT06665594 Dec 2025 → Nov 2026 expected University of Wisconsin, Madison Recruiting No outcome recorded
Phase 2 NCT06718751 Oct 2025 → Oct 2029 expected Baylor College of Medicine Not yet recruiting No outcome recorded
Phase 2 NCT06599762 Sep 2025 → Apr 2027 expected acute myeloid leukemia, myelodysplastic syndrome, myelodysplastic/myeloproliferative neoplasm University of Manitoba Recruiting No outcome recorded
Phase 2 NCT07263841 Jun → Dec 2025 overdue hyperpigmentation of the skin King Edward Medical University Active not recruiting No outcome recorded
Phase 2 NCT06644079 May 2025 → Apr 2026 skin squamous cell carcinoma University of Florida Withdrawn No outcome recorded
Phase 2 NCT06657924 Feb 2025 → Sep 2027 expected hemorrhagic disease, intestinal disorder, thrombotic disease Kristen Ban Recruiting No outcome recorded
Phase 2 NCT06057675 Mar 2024 → Jun 2026 overdue skin cancer Vanderbilt University Medical Center Recruiting No outcome recorded
Phase 2 NCT03822793 Dec 2023 → Apr 2025 arthropathy University Hospital of Saint-Etienne Completed No outcome recorded
Phase 2 NCT05794321 Sep 2023 → May 2032 expected University of California, San Francisco Recruiting No outcome recorded
Phase 2 NCT05802238 Apr 2023 → Nov 2024 bone disorder Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) Withdrawn No outcome recorded
Phase 2/314 trials
Phase 2/3 NCT07212452 Aug → Oct 2025 University of Health Sciences Lahore Completed No outcome recorded
Phase 2/3 NCT06707051 Jan 2022 → Dec 2023 agranulocytosis, digestive system disorder, endometrial disorder, hemorrhagic disease +1 District Headquarters Teaching Hospital Sahiwal Completed No outcome recorded
Phase 2/3 NCT05047133 Sep 2021 → Jul 2022 overdue Ascension Health Recruiting No outcome recorded
Phase 2/3 NCT04599205 Dec 2020 → Dec 2021 hyperpigmentation of the skin Assiut University Unknown No outcome recorded
Phase 2/3 NCT04430777 Jan 2019 → Feb 2020 Total Definer Research Group Completed No outcome recorded
Phase 2/3 NCT03361345 Nov 2018 → Jan 2022 hyperpigmentation of the skin Wayne State University Withdrawn No outcome recorded
Phase 2/3 NCT04170088 Sep 2018 → May 2019 drug allergy Jinnah Postgraduate Medical Centre Completed No outcome recorded
Phase 2/3 NCT03353259 Nov 2017 → Feb 2021 Oslo University Hospital Terminated No outcome recorded
Phase 2/3 NCT02866838 Dec 2016 → Sep 2021 intracerebral hemorrhage University Hospital, Basel, Switzerland Completed No outcome recorded
Phase 2/3 NCT03351686 Aug 2016 → Apr 2017 Mansoura University Completed No outcome recorded
Phase 3104 trials
Phase 3 NCT04387305 Oct 2026 → Mar 2031 expected hemorrhagic disease, traumatic brain injury Daniel Nishijima, MD, MAS Not yet recruiting No outcome recorded
Phase 3 NCT07641946 Jul 2026 → Jul 2027 expected Assiut University Not yet recruiting No outcome recorded
Phase 3 NCT07672158 Jul 2026 → Aug 2028 expected cerebral palsy Murdoch Childrens Research Institute Not yet recruiting No outcome recorded
Phase 3 NCT07474077 May 2026 → Dec 2027 expected Sultan Qaboos University Not yet recruiting No outcome recorded
Phase 3 NCT06902714 Apr 2026 → Jul 2028 expected University of Alabama at Birmingham Recruiting No outcome recorded
Phase 3 NCT07423156 Mar → Aug 2026 overdue placenta praevia Allama Iqbal Medical College Not yet recruiting No outcome recorded
Phase 3 NCT06519422 Sep 2025 → Aug 2028 expected anemia London School of Hygiene and Tropical Medicine Not yet recruiting No outcome recorded
Phase 3 NCT06337838 Jun 2025 → Feb 2027 expected acute kidney injury, chronic kidney disease, hemorrhagic disease Hamilton Health Sciences Corporation Recruiting No outcome recorded
Phase 3 NCT06070350 Nov 2024 → Jun 2028 expected Philip Spinella Recruiting No outcome recorded
Phase 3 NCT06010368 Oct 2024 → Dec 2025 overdue Cairo University Not yet recruiting No outcome recorded
Phase 4137 trials
Phase 4 NCT07685743 Sep 2026 → Mar 2028 expected osteoarthritis, hip, osteoarthritis, knee Oregon Health and Science University Not yet recruiting No outcome recorded
Phase 4 NCT07644923 Aug 2026 → Aug 2028 expected NYU Langone Health Not yet recruiting No outcome recorded
Phase 4 NCT07696806 Jul 2026 → Jun 2027 expected hyperpigmentation of the skin Sameh Sarsik Enrolling by invitation No outcome recorded
Phase 4 NCT06832878 Jun 2026 overdue Mayo Clinic Not yet recruiting No outcome recorded
Phase 4 NCT07614087 May → Jun 2026 overdue osteoarthritis Hua Luo Not yet recruiting No outcome recorded
Phase 4 NCT07501884 May → Dec 2026 expected urethral stricture Amjad Alwaal, MD, MSc, FRCSC, FACS Not yet recruiting No outcome recorded
Phase 4 NCT07115056 Apr 2026 → Dec 2028 Campbell Clinic Withdrawn No outcome recorded
Phase 4 NCT07460518 Mar → Jun 2026 overdue anemia, benign prostatic hyperplasia Hamza Najout Not yet recruiting No outcome recorded
Phase 4 NCT07116395 Jan 2026 → Jun 2029 expected Arbi Nazarian, MD Not yet recruiting No outcome recorded
Phase 4 NCT07314424 Jan 2026 → Oct 2027 expected anemia Tang Xiaodong Not yet recruiting No outcome recorded
Show all 137 trials opens the full record — a long page
Phase not applicable112 trials
NCT07530016 Aug 2026 → Dec 2027 expected hyperpigmentation of the skin The First Affiliated Hospital of Xinxiang Medical College Not yet recruiting No outcome recorded
NCT07714473 Aug → Nov 2026 expected rotator cuff syndrome Hua Luo Not yet recruiting No outcome recorded
NCT07679139 Jul 2026 → Dec 2027 expected National Cheng-Kung University Hospital Not yet recruiting No outcome recorded
NCT07581457 Jun 2026 → May 2027 expected adolescent idiopathic scoliosis Poznan University of Medical Sciences Recruiting No outcome recorded
NCT07494032 May 2026 → May 2029 expected arthropathy NYU Langone Health Not yet recruiting No outcome recorded
NCT07540026 May 2026 → Dec 2027 expected upper digestive tract disorder National Cheng-Kung University Hospital Recruiting No outcome recorded
NCT07432737 Feb 2026 → May 2027 expected bone disorder University Hospital for Surgical Diseases St. Naum Ohridsk i- Skopje Recruiting No outcome recorded
NCT07390799 Feb → Aug 2026 overdue Ege University Not yet recruiting No outcome recorded
NCT07318467 Jan → Jun 2026 overdue Cairo University Not yet recruiting No outcome recorded
NCT07401394 Dec 2025 → Jun 2026 overdue hemorrhagic disease Santa Maria Hospital - GVM Care & Research Active not recruiting No outcome recorded
Show all 112 trials opens the full record — a long page
Also used as a comparator or background therapy in 248 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 06 trials
Phase 0 NCT07280234 Comparator Nov 2024 → May 2025 hyperpigmentation of the skin Hayat Abad Medical Complex, Peshawar Completed No outcome recorded
Phase 0 NCT06509256 Comparator Jul 2024 overdue urticaria Assiut University Not yet recruiting No outcome recorded
Phase 0 NCT06149091 Comparator Dec 2023 → Dec 2024 bronchial disorder China-Japan Friendship Hospital Unknown No outcome recorded
Phase 0 NCT06457360 Comparator Nov 2023 → Jan 2024 cirrhosis of liver British University In Egypt Completed No outcome recorded
Phase 0 NCT05427513 Comparator Apr 2022 → Dec 2023 Shaukat Khanum Memorial Cancer Hospital & Research Centre Unknown No outcome recorded
Phase 17 trials
Phase 1 NCT07002749 Comparator Jun 2025 overdue Patel Hospital, Pakistan Not yet recruiting No outcome recorded
Phase 1 NCT05884151 Comparator Nov 2022 → Apr 2023 hyperpigmentation of the skin Combined Military Hospital Abbottabad Completed No outcome recorded
Phase 1 NCT05887219 Comparator Nov 2022 → Apr 2023 hyperpigmentation of the skin Combined Military Hospital Abbottabad Completed No outcome recorded
Phase 1 NCT06920264 Comparator Jul 2021 → Sep 2024 St. Louis Joint Replacement Institute Completed No outcome recorded
Phase 1 NCT05362500 Comparator Jun → Nov 2021 hyperpigmentation of the skin Combined Military Hospital Abbottabad Completed No outcome recorded
Phase 1/26 trials
Phase 1/2 NCT06330935 Comparator Mar 2024 → Mar 2025 traumatic brain injury Mansoura University Unknown No outcome recorded
Phase 1/2 NCT04656067 Comparator Apr → Oct 2020 Egymedicalpedia Completed No outcome recorded
Phase 1/2 NCT04707950 Comparator Jan 2020 → Feb 2021 Benha University Unknown No outcome recorded
Phase 1/2 NCT03780894 Background Nov 2018 → Jan 2021 Blood and Tissue Bank of Catalonia Completed No outcome recorded
Phase 1/2 NCT02616731 Comparator Sep 2015 → Jan 2016 menstrual disorder Ain Shams University Unknown No outcome recorded
Phase 222 trials
Phase 2 NCT07127042 Comparator Aug 2025 → Dec 2026 expected ScinnoHub Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT07169383 Comparator Jun → Dec 2025 overdue hyperpigmentation of the skin Hina Malik Enrolling by invitation No outcome recorded
Phase 2 NCT07392034 Comparator Jan → Jun 2025 Nishtar Medical University Completed No outcome recorded
Phase 2 NCT06479161 Comparator Jun 2024 → Feb 2025 overdue Matthew Grosso, MD Recruiting No outcome recorded
Phase 2 NCT05909072 Comparator Jun → Nov 2023 hyperpigmentation of the skin Zagazig University Unknown No outcome recorded
Phase 2/311 trials
Phase 2/3 NCT07448415 Comparator Feb 2026 → Feb 2027 expected hyperpigmentation of the skin Assiut University Not yet recruiting No outcome recorded
Phase 2/3 NCT07245264 Comparator Dec 2025 → Nov 2028 expected St. Olavs Hospital Recruiting No outcome recorded
Phase 2/3 NCT07125508 Comparator Aug 2023 → Sep 2024 anemia, angiodysplasia of intestine Louisiana State University Health Sciences Center in New Orleans Completed No outcome recorded
Phase 2/3 NCT04742205 Comparator Feb 2021 → Dec 2023 intracerebral hemorrhage Kathmandu Medical College and Teaching Hospital Completed No outcome recorded
Phase 2/3 NCT04562610 Comparator Nov 2020 → Oct 2024 vertebral column disorder University of California, Davis Completed No outcome recorded
Phase 342 trials
Phase 3 NCT05713630 Comparator May 2026 → Mar 2027 expected Unity Health Toronto Recruiting No outcome recorded
Phase 3 NCT06622564 Comparator Jan 2025 → Jan 2026 overdue epilepsy, hemorrhagic disease Hamilton Health Sciences Corporation Not yet recruiting No outcome recorded
Phase 3 NCT05470816 Comparator Nov 2022 → Aug 2026 overdue dementia Bayside Health Active not recruiting No outcome recorded
Phase 3 NCT05648656 Comparator Feb 2022 → Jan 2023 Post Graduate Institute of Medical Education and Research, Chandigarh Unknown No outcome recorded
Phase 3 NCT04344860 Comparator Jun 2021 → Aug 2024 von Willebrand disease (hereditary or acquired) Nicoletta C Machin Completed No outcome recorded
Phase 484 trials
Phase 4 NCT07522788 Comparator Jun → Nov 2026 expected hyperpigmentation of the skin Hayatabad Medical Complex Not yet recruiting No outcome recorded
Phase 4 NCT06894719 Comparator Jun → Dec 2026 expected Rush University Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07332910 Comparator Jan → Jun 2026 overdue hemarthrosis Chirec Not yet recruiting No outcome recorded
Phase 4 NCT07078942 Comparator Jul 2025 → Jul 2026 overdue Chulalongkorn University Not yet recruiting No outcome recorded
Phase 4 NCT07089251 Comparator Jul 2025 → Jun 2027 expected osteoarthritis, knee King Abdullah International Medical Research Center Recruiting No outcome recorded
Phase not applicable70 trials
NCT07495748 Comparator Jul → Dec 2026 expected hyperpigmentation of the skin Foundation University Islamabad Not yet recruiting No outcome recorded
NCT07540702 Comparator Feb → Aug 2026 overdue hyperpigmentation of the skin Kasr El Aini Hospital Recruiting No outcome recorded
NCT07365150 Comparator Jan 2026 → Jun 2027 expected intracerebral hemorrhage The University of Hong Kong Recruiting No outcome recorded
NCT07192640 Comparator Oct 2025 → Feb 2026 overdue hemorrhagic disease, obesity disorder Ain Shams University Not yet recruiting No outcome recorded
NCT06208267 Comparator Aug 2025 → Apr 2027 expected esophageal varices with bleeding St. Mary's Research Center, Canada Recruiting No outcome recorded

Evidence & citations 37 cited values

Every value below carries the sentence it was read from. 770 sources stand behind the page.

FieldValueCited text
Known as Tranexamic Acid “Effects of Co-administered Sublingual Misoprostol and Intravenous Tranexamic Acid on Prevention of Postpartum Hemorrhage in Pregnant Women With Twin Pregnancy Undergoing...” NCT03774524
684

“Whole Blood Clot Stability and Thrombin Generating Capacity Following Treatment With Bypassing Agents (BPA) With and Without and Tranexamic Acid (TXA) in Haemophilia A Patients...” NCT01800435

“The aim of this study is to compare the effectiveness of combined tranexamic acid (TA) and oxytocin infusion with intravenous carbetocin for prevention of PPH in patients with...” NCT03777878

“OBJECTIVE: To estimate the effects of adding intravenous tranexamic acid (TA) to the standard active management of third-stage labor to reduce vaginal blood loss during the...” PMID 23023559 Sep 2012

Tranexamic acid (TXA) has been routinely delivered in multisegmental spinal decompression and bone graft fusion surgeries with satisfactory outcomes in minimizing gross blood...” PMID 30755256 Feb 2019

“Patients in the experimental group will receive a loading dose of tranexamic acid (TXA) at a concentration of 1g/10ml over a period of 10 minutes, administered immediately...” NCT05794321

“Group (II): patients received 1 gm tranexamic acid (TA), (2 ampoules of Capron® 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision plus Intrauterine Inflated...” NCT03741114

“10 mg/kg tranexamic acid (Transamine 10% IV/IM Injectable Solution) will be placed into 100 cc physiological saline through the appropriate vascular access and injected within...” NCT06434636

Tranexamic acid will be given as per unit protocol, (currently 1g pre-operatively IV and 500mg orally at 8 hours post op. unless contraindicated by a high risk of thrombosis.)” NCT02288923

“To determine whether intraoperative tranexamic acid (TXA) administration reduced intraoperative blood loss in patients undergoing large meningioma resection.” PMID 42115323 May 2026

“Patient will receive an intravenous perfusion of 300 mg Exacyl (tranexamic acid) intravenous (IV) over 9 minutes, starting at the time of surgical incision.” NCT03822793

“Oral administration of 2 grammes tranexamic acid 2 hours before skin incision and 2 grammes oral tranexamic acid 4 hours after first administration” NCT04855877

Tranexamic acid (TXA) is a drug that has proved useful in reducing bleeding associated with other surgeries and CRT results have been positive” NCT01199627

“Subjects will be given the therapeutic dose of tranexamic acid for menorrhagia, which is 1300 mg PO TID for up to 5 days during menstruation” NCT05309525

“single dose of 20ug/kg of recombinant factor VIIa along with tranexamic acid of 4 gram a day for 7 days following surgery” NCT01538160

Tranexamic acid (Amchafibrin) exerts an antihemorrhagic activity by inhibiting the fibrinolytic properties of plasmin.” NCT03386656

“These medications are Ofirmev ( acetaminophen ) 1,000mg and tranexamic acid 2,000 mg , an antifibrinolytic drug.” NCT04562610

“Intravenous and topical tranexamic acid (TXA) have been well established in reducing blood loss postoperatively.” NCT03074994

Tranexamic acid (TA) is an antifibrinolytic agent that blocks the lysine-binding site of plasminogen to fibrin.” NCT03870256

Tranexamic acid and Etamsylate are slowly given intravenously 10 minutes before start of Cesarean Delivery” NCT05273632

“Patients randomized to the IV TXA group will receive intravenous Tranexamic acid during the procedure.” NCT07131592

Tranexamic acid (TXA) reduces blood loss and transfusion in paediatric craniosynostosis surgery.” PMID 32620262 Jun 2020

Tranexamic acid will be used in aconcentration of 4mg/ml ,1ml will be used fo half of the face.” NCT03923062

“A gauze soaked with 2 g tranexamic acid (20 ml) diluted in 100 ml of sodium chloride0.9%” NCT03880045

Tranexamic Acid Versus Placebo to Reduce Perioperative Bleeding After Major Hepatectomy” NCT00657384

“Topical tranexamic acid (TXA) and ascorbic acid are both effective in treating melasma” NCT07522788

“0.5g of tranexamic acid is administered locally after dilution before surgical closure” NCT07314424

Tranexamic acid (TXA) reduces bleeding and transfusion requirements in established PPH” PMID 36934142 Mar 2023

“Intravenous tranexamic acid (TXA) reduces bleeding deaths after injury and childbirth.” PMID 33010927 Sep 2020

“will receive 1 g tranexamic acid (2 ampoules of kapron 500 mg, kapron®, Amoun, Egypt)” NCT05806307

“Intraosseous injection of Ketorolac 15mg and Tranexamic acid 500mg in femoral canal” NCT06243575

“2g of sucralfate powder and 1g of tranexamic acid powder will be sprayed after EST” NCT06107504

Tranexamic acid (TXA), an antifibrinolytic agent, reduces perioperative bleeding” NCT07288697

“the use of topical and intravenous (IV) Tranexamic Acid (TXA) in spine surgery.” NCT02093988

“1.3 mg oral tranexamic acid or 1.0 mg oral estradiol three times a day” NCT01659008

tranexamic acid (TXA) nebulization to control bleeding in hemoptysis.” PMID 41221568 Oct 2025

“1-gram tranexamic acid (10 ml) in 100 ml saline infusion” NCT03880604

Tranexamic acid belongs to fibrinolytic inhibitors.” NCT00308880

“1 gm of tranexamic acid in 100 ml saline iv” NCT03777696

Tranexamic acid intravenous administration” NCT05806346

Tranexamic acid injection 8-10mg/kg” NCT05957822

Tranexamic Acid 500 mg” NCT06369012

tranexamic acid(TXA)” NCT05138913

Tranexamic AcidNCT03825939

NCT03553186

NCT03765021

NCT04338074

NCT06894719

NCT05072873

NCT02781597

NCT06000423

NCT02930941

NCT03109652

NCT01651182

NCT05429580

NCT06479161

NCT07442643

NCT02063035

NCT03353259

NCT01713101

NCT05874583

NCT02286973

NCT07423156

NCT04907812

NCT04898712

NCT01370460

NCT02053363

NCT04986813

NCT03741075

NCT04560465

NCT03899233

NCT04549012

NCT06618820

NCT03690037

NCT02780245

NCT00994994

NCT07089251

NCT06580509

NCT01940523

NCT03060889

NCT04488367

NCT04753151

NCT07002749

NCT04489108

NCT03019198

NCT04373603

NCT01940419

NCT03580018

NCT01940536

NCT05913466

NCT02903017

NCT04319614

NCT02908516

NCT01085006

NCT03112135

NCT04951128

NCT03216083

NCT03580590

NCT07192640

NCT02146456

NCT04427618

NCT02026297

NCT06736860

NCT03970213

NCT04724772

NCT04187014

NCT04372940

NCT04149171

NCT01813058

NCT04494126

NCT02561923

NCT06088407

NCT02125890

NCT04754230

NCT03656445

NCT06091891

NCT04560010

NCT07672158

NCT00755209

NCT04771923

NCT03413891

NCT05397652

NCT03632824

NCT04089865

NCT03326596

NCT01658124

NCT03463993

NCT01881568

NCT02422056

NCT03774706

NCT06519422

NCT03113253

NCT04559880

NCT03708497

NCT03801122

NCT07157631

NCT06777966

NCT01655927

NCT04742205

NCT01651806

NCT03328832

NCT02829346

NCT02492087

NCT04610164

NCT01683955

NCT06301204

NCT00375258

NCT01655641

NCT05672407

NCT03582293

NCT03934047

NCT06644079

NCT07390799

NCT06109155

NCT01683747

NCT02427412

NCT01258010

NCT03540368

NCT03856164

NCT01599468

NCT05639686

NCT02650856

NCT02261415

NCT05072860

NCT02584725

NCT02627560

NCT06188052

NCT01846507

NCT03585179

NCT05448456

NCT04100447

NCT04550338

NCT03182751

NCT06653699

NCT06270407

NCT05302986

NCT03965767

NCT06509256

NCT06452342

NCT01964781

NCT04188184

NCT01873768

NCT06421389

NCT05909072

NCT06657924

NCT01326403

NCT01067638

NCT02219152

NCT01596738

NCT03361345

NCT06718751

NCT03469947

NCT05594186

NCT06149091

NCT03351686

NCT02966236

NCT07392034

NCT01937559

NCT01998438

NCT03646474

NCT06622564

NCT01060176

NCT05554211

NCT00375466

NCT04902950

NCT06070350

NCT05236569

NCT02840097

NCT00375440

NCT04911413

NCT02625948

NCT02314988

NCT04803747

NCT05598086

NCT02936661

NCT04803591

NCT06983886

NCT04419246

NCT07448415

NCT05075200

NCT05507983

NCT03849443

NCT05441592

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NCT04201951

NCT02753816

NCT07625709

NCT02546648

NCT07401394

NCT02678208

NCT05705336

NCT04696224

NCT02086500

Known as 1,4-amino-carboxylic acid 1,4-amino-carboxylic acid (tranexamic acid)” PMID 23917458 Sep 2014
Known as Acide Tranexamique ClinicalTrials.gov intervention name — accepted as the source's own label NCT04085575
Known as AMCA “Tranexamic acid (AMCA) is a potent antifibrinolytic drug” PMID 3321402 1987
Known as Amchafibrin “Tranexamic acid (Amchafibrin) exerts an antihemorrhagic activity by inhibiting the fibrinolytic properties of plasmin.” NCT03386656
Known as AXA “Tranexamic acid (AXA) and aminocaproic acid (EACA) are synthetic drugs derived from Lysine that competitively inhibit the lysine receptors in the plasminogen and plasmin...” NCT03365999
Known as Capron “Group (II): patients received 1 gm tranexamic acid (TA), (2 ampoules of Capron® 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision plus Intrauterine Inflated...” NCT03741114
3

“1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision” NCT03706339

“1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision” NCT03710330

“1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Amoun, Cairo, Egypt)” NCT03570710

Known as Cyclokapron CyclokapronNCT05323149
1

NCT00697385

Known as Cyklo-f “Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 2003
Known as Cyklokapron “Patients in the TXA group will be given 15 mg/kg of tranexamic acid (Cyklokapron@; Amoun Pharmaceutical Co., SAE) slowly intravenously 30 min before surgery followed by 10 mg/...” NCT03892668
9

“Subjects will be randomized in a 1:1:1:1 ratio to receive either DepoTXA 400 mg, DepoTXA 800 mg, DepoTXA 1200 mg, or IV TXA (Cyklokapron® 1 gram).” NCT02922582

“Standard surgery using burr-hole procedure, irrigation and drainage combined withTranexamic acid (Cyklokapron) administration.” NCT03353259

“Tranexamic acid (Cyklokapron) is utilized extensively for menorrhagia in Australia and the United Kingdom.” NCT00111215

“1 gm of Tranexamic Acid (Cyklokapron) that will be dissolved in 50 ml of injectable 0.9% saline” NCT05913466

“Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 2003

“topical tranexamic acid (TXA - Cyklokapron; Pfizer, New York, NY)” NCT05357079

“Tranexamic Acid Injection [Cyklokapron]” NCT05464394

“Tranexamic Acid (Cyklokapron)” NCT07245264

“Tranexamic Acid (Cyklokapron)” NCT02053363

Known as Cyklokapron (tranexamic acid) Cyklokapron (tranexamic acid)NCT01535781
Known as EXACYL “Patient will receive an intravenous perfusion of 300 mg Exacyl (tranexamic acid) intravenous (IV) over 9 minutes, starting at the time of surgical incision.” NCT03822793
7

“IV Tranexamic acid (Exacyl®): 1 gram diluted in 20 mL saline solution, in 30 minutes, five minutes before skin incision and a second 1 gram, 3 hours later.” NCT02428868

“Tranexamic acid (TA) (Exacyl® Sanofi France), an antifibrinolytic drug, reduces bleeding and transfusion need in major surgery and trauma (1).” NCT02797119

“intravenous administration of 10-mL of tranexamic acid (EXACYL® 1 g/10 ml I.V., solution injectable)” NCT03431805

“Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 2003

“Active comparator : Tranexamic Acid (Exacyl)” NCT02252497

NCT02403596

NCT01940692

Known as Group T ClinicalTrials.gov intervention name — accepted as the source's own label NCT02003313
Known as Kapron “In Tranexamic group (n=111), patients will be given 1 gm (10 ml) TXA (Kapron, Amoun, Egypt) diluted in 20 ml of Glucose 5% (administered as intravenous infusion over 5 minutes,...” NCT06060327
6

“Women assigned to the study group will receive 1 gr of TXA injection (Kapron, AMOUN Pharmaceutical co.) given slowly I.V over 10 minutes before the operation.” NCT02350179

“Tranexamic acid (Kapron ampoules, 100 mg/mL) is diluted under aseptic conditions to a final concentration of 10 mg/mL” NCT07540702

“soaked in Tranexamic acid (Kapron, Amoun Pharmaceuticals SAE, Egypt. 5ml Amp, 100mg /1ml)” NCT05439694

“will receive 1 g tranexamic acid (2 ampoules of kapron 500 mg, kapron®, Amoun, Egypt)” NCT05806307

“using a sterile towel soaked with 2g tranexamic acid (Kapron, Amoun, Cairo, Egypt)” NCT06515535

“Tranexamic acid (Kapron, Amoun Pharmaceuticals SAE, Egypt. 5ml Amp, 100mg /1ml)” NCT05434533

Known as Kepron “Tranexamic acid (Kepron, Amoun, Egypt) was given slowly intravenously over 10 minutes just before the skin incision of elective cesarean section to group A.” NCT03351686
Known as LB1148 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02836470
3

NCT05056935

NCT05470387

NCT04390217

Known as Lysteda “Medications: tranexamic acid (Lysteda, Pierre Fabre Mexico) or aminocaproic acid (Amikar, Wyeth), as appropriate, will be administered orally three times (administering 2...” NCT03365999
Known as Marcan-Tranexamic Acid Marcan-Tranexamic Acid 500 mg oral tablet over-encapsulated to match the placebo.” NCT05713630
Known as Sandoz-Tranexamic Acid Sandoz-Tranexamic Acid 100 mg/mL solution for injection via intravenous (IV) added to a 100mL infusion bag of NaCl 0.9% and infused by slow intravenous injection over 20 minutes.” NCT05713630
Known as TNA “Tranexamic acid (TNA) is an antifibrinolytic agent that inhibits fibrinolysis by blocking the activation of plasminogen.” NCT07174895
1

“Despite the documented blood-saving effects of tranexamic acid (TNA) in total knee arthroplasty (TKA)” PMID 23592025 Apr 2013

Known as tnx acid “group 1 (TRANEXEL 250 mg/5 mL) patients administered 250 mg tnx acid during the whole bimaxillary orthognathic surgery” NCT06301204
Known as TRAN “BACKGROUND: To assess the equivalence of tranexamic acid (TRAN) versus synthetic oxytocin (OXY) in reducing post-partum blood loss, in full-term patients (37-42 weeks), at low...” PMID 38873634 May 2024
Known as Tranexam OrPha “Tranexamic acid 10mg/kg (Tranexam OrPha 1000 mg/10 ml, OrPha Swiss GmbH, Küsnacht, Switzerland) will be administered 15 -30 minutes prior to surgery followed by infusion of...” NCT04625530
Known as Tranexamic acid (CYKLOKAPRON) (Pfizer, New York, NY). Tranexamic acid (CYKLOKAPRON) (Pfizer, New York, NY).NCT06419075
Known as tranexamic acid (TXA) tranexamic acid (TXA)NCT05639686
1

NCT03063892