Tranexamic Acid
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | CYKLOKAPRON | — | 1986-12-30 | fda.gov ↗ |
Trials 446 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 018 trials | ||||||
| Phase 0 | NCT07565753 | Jul 2026 → Sep 2027 expected | bleeding disorder, vascular-type, tonsillitis | The University of Texas Health Science Center at San Antonio | Recruiting | No outcome recorded |
| Phase 0 | NCT07362992 | Jul 2026 → Dec 2028 expected | — | Wolfson Medical Center | Recruiting | No outcome recorded |
| Phase 0 | NCT06580509 | Feb 2026 → Sep 2027 expected | bleeding disorder, vascular-type, tonsillitis | The University of Texas Health Science Center at San Antonio | Recruiting | No outcome recorded |
| Phase 0 | NCT06725732 | Jan → Dec 2025 overdue | — | Assiut University | Recruiting | No outcome recorded |
| Phase 0 | NCT06345833 | Jul 2024 → Jul 2026 overdue | hemophilia, hemorrhagic disease | University of Minnesota | Recruiting | No outcome recorded |
| Phase 0 | NCT06097611 | Nov 2023 → Nov 2024 | — | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT04630886 | Jun 2021 → Jan 2024 | skin neoplasm | Riley McLean | Terminated | No outcome recorded |
| Phase 0 | NCT04797156 | Mar 2021 → Aug 2024 | — | Icahn School of Medicine at Mount Sinai | Completed | No outcome recorded |
| Phase 0 | NCT04541303 | Oct 2020 → Dec 2021 | — | University of Missouri-Columbia | Completed | No outcome recorded |
| Phase 0 | NCT04488367 | Jul 2020 → Jul 2023 | bone disorder | Community Memorial Health System | Unknown | No outcome recorded |
| Phase 0 | NCT04178655 | Nov 2019 → Nov 2022 | — | Rabin Medical Center | Unknown | No outcome recorded |
| Phase 0 | NCT03849443 | Aug 2019 → Dec 2026 expected | — | Rush University Medical Center | Recruiting | No outcome recorded |
| Phase 0 | NCT03580590 | Sep 2018 → Nov 2019 | orthostatic hypotension 2 | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT05357079 | Aug 2017 → Aug 2024 | — | University of Cincinnati | Completed | No outcome recorded |
| Phase 0 | NCT03128866 | May 2017 → May 2026 overdue | — | M.D. Anderson Cancer Center | Active not recruiting | No outcome recorded |
| Phase 0 | NCT02911831 | Nov 2016 → Apr 2022 | — | Northwestern University | Completed | No outcome recorded |
| Phase 0 | NCT02093988 | Aug 2015 → Feb 2017 | — | University of British Columbia | Unknown | No outcome recorded |
| Phase 0 | NCT02319915 | Feb 2015 → Mar 2017 | — | Brugmann University Hospital | Completed | No outcome recorded |
| Phase 16 trials | ||||||
| Phase 1 | NCT05774717 | Apr 2023 → Apr 2029 expected | — | Vanderbilt University Medical Center | Recruiting | No outcome recorded |
| Phase 1 | NCT03777488 | Oct 2019 → Oct 2020 | — | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 1 | NCT04100447 | Nov 2018 → Mar 2020 | ileus | Ronald Hurst, MD, FACS | Completed | No outcome recorded |
| Phase 1 | NCT02561923 | Aug 2015 → Jun 2016 | — | Janssen Scientific Affairs, LLC | Completed | No outcome recorded |
| Phase 1 | NCT02620748 | Mar 2015 → Feb 2018 | leiomyoma | George Washington University | Completed | No outcome recorded |
| Phase 1 | NCT01683955 | Jan → Nov 2013 | anemia, osteoarthritis, hip | Henry Ford Health System | Completed | No outcome recorded |
| Phase 1/210 trials | ||||||
| Phase 1/2 | NCT06983886 | May 2025 → Jun 2026 overdue | — | Ramathibodi Hospital | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT06997796 | May → Dec 2025 overdue | — | Dr. Anne Conlin | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06023212 | Dec 2023 → Jan 2026 overdue | metastatic malignant neoplasm in the spinal cord | Second Affiliated Hospital, School of Medicine, Zhejiang University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT04555343 | Mar → Sep 2021 | prostate cancer, urinary bladder cancer, urinary tract obstruction | Fraser Health | Completed | No outcome recorded |
| Phase 1/2 | NCT03875937 | Sep 2019 → Feb 2020 | — | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 1/2 | NCT03806556 | Apr 2019 → Aug 2020 | acquired coagulation factor deficiency, childhood malignant neoplasm, hemorrhagic disease, thrombocytopenia | Meghan McCormick | Terminated | No outcome recorded |
| Phase 1/2 | NCT02604719 | Nov 2015 → May 2016 | — | Ahmed Alanwar | Unknown | No outcome recorded |
| Phase 1/2 | NCT02688127 | Aug 2015 → Feb 2016 | pregnancy disorder | Medical Research Council | Completed | No outcome recorded |
| Phase 1/2 | NCT02350179 | Jun 2014 → Apr 2015 | perianal hematoma | Ain Shams University | Unknown | No outcome recorded |
| Phase 1/2 | NCT01085006 | Sep 2009 → Aug 2010 | hemorrhagic disease | Tehran University of Medical Sciences | Completed | No outcome recorded |
| Phase 245 trials | ||||||
| Phase 2 | NCT06665594 | Dec 2025 → Nov 2026 expected | — | University of Wisconsin, Madison | Recruiting | No outcome recorded |
| Phase 2 | NCT06718751 | Oct 2025 → Oct 2029 expected | — | Baylor College of Medicine | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06599762 | Sep 2025 → Apr 2027 expected | acute myeloid leukemia, myelodysplastic syndrome, myelodysplastic/myeloproliferative neoplasm | University of Manitoba | Recruiting | No outcome recorded |
| Phase 2 | NCT07263841 | Jun → Dec 2025 overdue | hyperpigmentation of the skin | King Edward Medical University | Active not recruiting | No outcome recorded |
| Phase 2 | NCT06644079 | May 2025 → Apr 2026 | skin squamous cell carcinoma | University of Florida | Withdrawn | No outcome recorded |
| Phase 2 | NCT06657924 | Feb 2025 → Sep 2027 expected | hemorrhagic disease, intestinal disorder, thrombotic disease | Kristen Ban | Recruiting | No outcome recorded |
| Phase 2 | NCT06057675 | Mar 2024 → Jun 2026 overdue | skin cancer | Vanderbilt University Medical Center | Recruiting | No outcome recorded |
| Phase 2 | NCT03822793 | Dec 2023 → Apr 2025 | arthropathy | University Hospital of Saint-Etienne | Completed | No outcome recorded |
| Phase 2 | NCT05794321 | Sep 2023 → May 2032 expected | — | University of California, San Francisco | Recruiting | No outcome recorded |
| Phase 2 | NCT05802238 | Apr 2023 → Nov 2024 | bone disorder | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | Withdrawn | No outcome recorded |
| Phase 2 | NCT05370820 | Dec 2022 → Nov 2026 expected | — | Inova Health Care Services | Recruiting | No outcome recorded |
| Phase 2 | NCT05554211 | Jul 2022 → Jul 2024 | breast cancer, hereditary breast ovarian cancer syndrome | Northwestern University | Withdrawn | No outcome recorded |
| Phase 2 | NCT04863339 | Mar → Apr 2022 | pituitary tumor | University of North Carolina, Chapel Hill | Withdrawn | No outcome recorded |
| Phase 2 | NCT05075200 | Dec 2021 → Oct 2022 | osteoarthritis, hip, osteoarthritis, knee | Sunnybrook Health Sciences Centre | Completed | No outcome recorded |
| Phase 2 | NCT04390217 | Oct → Dec 2021 | COVID-19, pneumonia | Leading BioSciences, Inc | Withdrawn | No outcome recorded |
| Phase 2 | NCT04338126 | Sep → Dec 2021 | COVID-19 | University of Alabama at Birmingham | Withdrawn | No outcome recorded |
| Phase 2 | NCT04898712 | Jul 2021 → Dec 2023 | — | Unity Health Toronto | Unknown | No outcome recorded |
| Phase 2 | NCT04274335 | Dec 2020 → Jun 2021 | — | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 2 | NCT04338074 | Jun 2020 → Apr 2021 | COVID-19 | University of Alabama at Birmingham | Terminated | No outcome recorded |
| Phase 2 | NCT04233749 | Mar 2020 → Dec 2025 overdue | lichen planus pigmentosus | Henry Ford Health System | Recruiting | No outcome recorded |
| Phase 2 | NCT02918201 | Jan 2020 → Jun 2022 | — | St. Olavs Hospital | Completed | No outcome recorded |
| Phase 2 | NCT04054687 | Nov 2019 → Apr 2021 | — | Mercy Health Ohio | Suspended | No outcome recorded |
| Phase 2 | NCT02836470 | Oct 2019 → Sep 2023 | ileus | Palisade Bio | Completed | No outcome recorded |
| Phase 2 | NCT03552705 | Aug 2019 → Jan 2027 expected | — | Stanford University | Recruiting | No outcome recorded |
| Phase 2 | NCT05056935 | Jul 2019 → Jul 2020 | ileus | Newsoara Biopharma Co., Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT03801122 | Mar 2019 → Mar 2022 | hematopoietic and lymphoid cell neoplasm | University Hospital of Saint-Etienne | Completed | No outcome recorded |
| Phase 2 | NCT02840097 | Mar 2019 → Oct 2020 | hemorrhagic disease, traumatic brain injury | Daniel Nishijima, MD, MAS | Completed | No outcome recorded |
| Phase 2 | NCT04560465 | Jun 2018 → May 2019 | — | Alex Ekwueme Federal University Teaching Hospital | Completed | No outcome recorded |
| Phase 2 | NCT03069859 | Mar 2018 → Dec 2019 | — | Sunnybrook Health Sciences Centre | Unknown | No outcome recorded |
| Phase 2 | NCT03287336 | Jan 2018 → Sep 2023 | — | George Washington University | Completed | No outcome recorded |
| Phase 2 | NCT03101124 | May 2017 → Feb 2018 | hemorrhagic disease | St. Olavs Hospital | Completed | No outcome recorded |
| Phase 2 | NCT03074994 | Oct 2016 → Jun 2019 | osteoarthritis, knee | Thammasat University | Unknown | No outcome recorded |
| Phase 2 | NCT02535949 | Feb 2016 → Jul 2017 | hemorrhagic disease | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 2 | NCT02393963 | Jul 2015 → Jul 2016 | osteoarthritis | Orthopaedic Innovation Centre | Completed | No outcome recorded |
| Phase 2 | NCT01990768 | May 2015 → Nov 2017 | traumatic brain injury | University of Washington | Completed | No outcome recorded |
| Phase 2 | NCT01089140 | Nov 2014 | scoliosis | The Hospital for Sick Children | Terminated | No outcome recorded |
| Phase 2 | NCT02219152 | Sep 2014 → Jan 2020 | — | Liran Levy | Unknown | No outcome recorded |
| Phase 2 | NCT02026297 | Jul 2014 → Jul 2015 | — | Brigham and Women's Hospital | Terminated | No outcome recorded |
| Phase 2 | NCT02323373 | Jun → Nov 2014 | osteoarthritis | Irmandade da Santa Casa de Misericordia de Sao Paulo | Completed | No outcome recorded |
| Phase 2 | NCT01728636 | Jan 2013 → Dec 2017 | scoliosis | Northwestern University | Completed | No outcome recorded |
| Phase 2 | NCT02829346 | Oct 2012 → Oct 2013 | osteoarthritis, knee | Thammasat University | Completed | No outcome recorded |
| Phase 2 | NCT01683747 | Jun 2012 → Nov 2014 | hypotensive disorder, infectious disease with sepsis | San Diego Veterans Healthcare System | Terminated | No outcome recorded |
| Phase 2 | NCT01866943 | Nov 2011 → Oct 2016 | — | Northwell Health | Terminated | No outcome recorded |
| Phase 2 | NCT01370460 | Jun 2011 → Sep 2012 | anemia, osteoarthritis, knee | Henry Ford Health System | Completed | No outcome recorded |
| Phase 2 | NCT01141127 | Jun 2010 → Dec 2011 | hemorrhagic disease | Centre Chirurgical Marie Lannelongue | Completed | No outcome recorded |
| Phase 2/314 trials | ||||||
| Phase 2/3 | NCT07212452 | Aug → Oct 2025 | — | University of Health Sciences Lahore | Completed | No outcome recorded |
| Phase 2/3 | NCT06707051 | Jan 2022 → Dec 2023 | agranulocytosis, digestive system disorder, endometrial disorder, hemorrhagic disease +1 | District Headquarters Teaching Hospital Sahiwal | Completed | No outcome recorded |
| Phase 2/3 | NCT05047133 | Sep 2021 → Jul 2022 overdue | — | Ascension Health | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04599205 | Dec 2020 → Dec 2021 | hyperpigmentation of the skin | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT04430777 | Jan 2019 → Feb 2020 | — | Total Definer Research Group | Completed | No outcome recorded |
| Phase 2/3 | NCT03361345 | Nov 2018 → Jan 2022 | hyperpigmentation of the skin | Wayne State University | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT04170088 | Sep 2018 → May 2019 | drug allergy | Jinnah Postgraduate Medical Centre | Completed | No outcome recorded |
| Phase 2/3 | NCT03353259 | Nov 2017 → Feb 2021 | — | Oslo University Hospital | Terminated | No outcome recorded |
| Phase 2/3 | NCT02866838 | Dec 2016 → Sep 2021 | intracerebral hemorrhage | University Hospital, Basel, Switzerland | Completed | No outcome recorded |
| Phase 2/3 | NCT03351686 | Aug 2016 → Apr 2017 | — | Mansoura University | Completed | No outcome recorded |
| Phase 2/3 | NCT02568124 | Nov 2015 → Dec 2024 | — | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | Unknown | No outcome recorded |
| Phase 2/3 | NCT02053363 | Mar 2014 → Jun 2020 | — | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 2/3 | NCT01869413 | Jun 2013 → Jan 2021 | urinary bladder cancer | Ottawa Hospital Research Institute | Completed | No outcome recorded |
| Phase 2/3 | NCT01655641 | Jul 2012 → Jun 2013 | colon carcinoma, gastric cancer, hepatocellular carcinoma, malignant pancreatic neoplasm | Tribhuvan University Teaching Hospital, Institute Of Medicine. | Unknown | No outcome recorded |
| Phase 3104 trials | ||||||
| Phase 3 | NCT04387305 | Oct 2026 → Mar 2031 expected | hemorrhagic disease, traumatic brain injury | Daniel Nishijima, MD, MAS | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07641946 | Jul 2026 → Jul 2027 expected | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07672158 | Jul 2026 → Aug 2028 expected | cerebral palsy | Murdoch Childrens Research Institute | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07474077 | May 2026 → Dec 2027 expected | — | Sultan Qaboos University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06902714 | Apr 2026 → Jul 2028 expected | — | University of Alabama at Birmingham | Recruiting | No outcome recorded |
| Phase 3 | NCT07423156 | Mar → Aug 2026 overdue | placenta praevia | Allama Iqbal Medical College | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06519422 | Sep 2025 → Aug 2028 expected | anemia | London School of Hygiene and Tropical Medicine | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06337838 | Jun 2025 → Feb 2027 expected | acute kidney injury, chronic kidney disease, hemorrhagic disease | Hamilton Health Sciences Corporation | Recruiting | No outcome recorded |
| Phase 3 | NCT06070350 | Nov 2024 → Jun 2028 expected | — | Philip Spinella | Recruiting | No outcome recorded |
| Phase 3 | NCT06010368 | Oct 2024 → Dec 2025 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06618820 | Sep 2024 → Dec 2025 overdue | osteoarthritis, knee | Campbell Clinic | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT06414031 | Jun 2024 → Nov 2026 expected | anemia, digestive system disorder | Ulrich Ronellenfitsch, MD | Recruiting | No outcome recorded |
| Phase 3 | NCT05562609 | Apr 2024 → Aug 2025 overdue | — | London School of Hygiene and Tropical Medicine | Recruiting | No outcome recorded |
| Phase 3 | NCT06422273 | Apr 2024 → Jun 2026 overdue | — | Corewell Health West | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT06229483 | Apr 2024 → Jan 2027 expected | brain neoplasm, hemorrhagic disease | Stephen Lownie | Recruiting | No outcome recorded |
| Phase 3 | NCT06266546 | Mar 2024 → Mar 2025 overdue | lung disorder, respiratory tract neoplasm | Youssef Yammine | Active not recruiting | No outcome recorded |
| Phase 3 | NCT05710146 | Dec 2023 → Mar 2024 | arthropathy, chronic pain syndrome | Northwestern University | Withdrawn | No outcome recorded |
| Phase 3 | NCT06143787 | Nov 2023 → Dec 2024 | bleeding disorder, vascular-type | Hyloris Developments | Unknown | No outcome recorded |
| Phase 3 | NCT05899465 | Aug 2023 → Sep 2026 expected | melanoma | University of Aarhus | Recruiting | No outcome recorded |
| Phase 3 | NCT05811676 | Jul 2023 → Feb 2025 | placenta praevia | Guangzhou Medical University | Completed | No outcome recorded |
| Phase 3 | NCT06010810 | Jun → Sep 2023 | hyperpigmentation of the skin | Indonesia University | Unknown | No outcome recorded |
| Phase 3 | NCT05816668 | Apr 2023 → Apr 2024 | prostate cancer | Cancer Institute of the State of São Paulo | Unknown | No outcome recorded |
| Phase 3 | NCT05302986 | Feb 2023 → Jul 2025 | — | Elsan | Completed | No outcome recorded |
| Phase 3 | NCT05053867 | Oct 2022 → Jul 2027 expected | cancer, lower respiratory tract disorder | M.D. Anderson Cancer Center | Recruiting | No outcome recorded |
| Phase 3 | NCT05464394 | Sep 2022 → Sep 2024 | hemorrhagic disease | Franciscus Gasthuis | Unknown | No outcome recorded |
| Phase 3 | NCT04918576 | Aug 2022 → Aug 2024 | — | McMaster University | Unknown | No outcome recorded |
| Phase 3 | NCT04918589 | Aug 2022 → Aug 2024 | breast cancer | McMaster University | Unknown | No outcome recorded |
| Phase 3 | NCT05470387 | Jun 2022 → Mar 2023 | ileus | Palisade Bio | Terminated | No outcome recorded |
| Phase 3 | NCT05323149 | May 2022 → Sep 2027 expected | inflammatory disease | Assiut University | Recruiting | No outcome recorded |
| Phase 3 | NCT04961528 | Mar 2022 → Dec 2025 | — | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT04448184 | Feb 2022 → Feb 2027 expected | hematopoietic and lymphoid cell neoplasm | Ottawa Hospital Research Institute | Recruiting | No outcome recorded |
| Phase 3 | NCT05855590 | Jan 2022 | — | Mexican Social Security Institute | Unknown | No outcome recorded |
| Phase 3 | NCT05507983 | Dec 2021 → Jan 2025 | — | Maasstad Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT05024253 | Aug 2021 → Feb 2024 | Ewing sarcoma of bone, osteosarcoma | Children's Cancer Hospital Egypt 57357 | Completed | No outcome recorded |
| Phase 3 | NCT04625530 | Aug 2021 → Dec 2026 | female reproductive system neoplasm | University Hospital, Basel, Switzerland | Withdrawn | No outcome recorded |
| Phase 3 | NCT04550338 | Aug 2021 → Dec 2022 | COVID-19 | University of Alabama at Birmingham | Withdrawn | No outcome recorded |
| Phase 3 | NCT04910464 | Jun 2021 → Jan 2027 expected | infectious disease with sepsis | Assiut University | Recruiting | No outcome recorded |
| Phase 3 | NCT04905901 | May 2021 → Jun 2026 | bleeding disorder, vascular-type | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT04733157 | Mar → Dec 2021 | — | University of Zimbabwe | Completed | No outcome recorded |
| Phase 3 | NCT04410042 | Jan 2021 → Jan 2024 | bone cancer | St. Jude Children's Research Hospital | Terminated | No outcome recorded |
| Phase 3 | NCT04865380 | Jan → Dec 2021 | rotator cuff syndrome, shoulder impingement syndrome | University of Saskatchewan | Unknown | No outcome recorded |
| Phase 3 | NCT04635007 | Jan 2021 → Jun 2022 | — | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT04304625 | Aug 2020 → Jun 2027 expected | — | University Hospital, Bordeaux | Recruiting | No outcome recorded |
| Phase 3 | NCT04427618 | Jun 2020 → Oct 2021 | — | KK Women's and Children's Hospital | Completed | No outcome recorded |
| Phase 3 | NCT04311073 | Jun 2020 → Jul 2024 | leiomyoma | Eastern Virginia Medical School | Unknown | No outcome recorded |
| Phase 3 | NCT04290013 | Apr → Oct 2020 | uterine disorder | Cairo University | Unknown | No outcome recorded |
| Phase 3 | NCT04724772 | Feb 2020 → Jul 2023 | — | Northwestern University | Withdrawn | No outcome recorded |
| Phase 3 | NCT04610164 | Jun 2019 → Dec 2020 | — | Rothman Institute Orthopaedics | Unknown | No outcome recorded |
| Phase 3 | NCT06638749 | May 2019 → Dec 2020 | — | University of Kansas Medical Center | Withdrawn | No outcome recorded |
| Phase 3 | NCT03846973 | Dec 2018 → Jan 2021 | — | Hamad Medical Corporation | Completed | No outcome recorded |
| Phase 3 | NCT03425799 | Oct 2018 → Oct 2019 | — | Exela Pharma Sciences, LLC. | Terminated | No outcome recorded |
| Phase 3 | NCT03585179 | Aug 2018 → Dec 2019 | hyperpigmentation of the skin | Centro Dermatológico Dr. Ladislao de la Pascua | Unknown | No outcome recorded |
| Phase 3 | NCT03565276 | Jul 2018 → Mar 2019 | — | Mount Sinai Hospital, Canada | Completed | No outcome recorded |
| Phase 3 | NCT03553186 | Jul 2018 → Mar 2027 expected | lumbar spinal stenosis | Hospital for Special Surgery, New York | Recruiting | No outcome recorded |
| Phase 3 | NCT03463993 | Apr → Dec 2018 | — | University of Zimbabwe | Completed | No outcome recorded |
| Phase 3 | NCT03364491 | Mar 2018 → Jul 2021 | hemorrhagic disease, obstetric disorder | The George Washington University Biostatistics Center | Completed | No outcome recorded |
| Phase 3 | NCT03431805 | Mar 2018 → Jan 2020 | — | University Hospital, Bordeaux | Completed | No outcome recorded |
| Phase 3 | NCT02775773 | Jan → Dec 2018 | — | Azienda U.S.L. 1 di Massa e Carrara | Completed | No outcome recorded |
| Phase 3 | NCT03216083 | Jan 2018 → Nov 2022 | pelvic organ prolapse | Mount Sinai Hospital, Canada | Unknown | No outcome recorded |
| Phase 3 | NCT03386656 | Nov 2017 → May 2019 | osteoarthritis, knee | Fundación Pública Andaluza Progreso y Salud | Completed | No outcome recorded |
| Phase 3 | NCT02972294 | Mar 2017 → Sep 2021 | anemia, bone disorder | University Hospital, Angers | Terminated | No outcome recorded |
| Phase 3 | NCT03280212 | Mar 2017 → Mar 2018 | — | Unity Health Toronto | Unknown | No outcome recorded |
| Phase 3 | NCT02993341 | Nov 2016 → Mar 2019 | anemia | Sault Area Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02650791 | Oct 2016 → Jun 2019 | hematopoietic and lymphoid cell neoplasm | Ottawa Hospital Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT02503319 | Jan 2016 | — | Azienda U.S.L. 1 di Massa e Carrara | Withdrawn | No outcome recorded |
| Phase 3 | NCT02645552 | Jan 2016 → Dec 2017 | traumatic brain injury | RenJi Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT02403596 | Oct 2015 → Aug 2017 | — | University Hospital, Brest | Completed | No outcome recorded |
| Phase 3 | NCT02650856 | Sep 2015 → Mar 2017 | osteoarthritis | Autonomous University of Nuevo León | Completed | No outcome recorded |
| Phase 3 | NCT02086500 | Jul 2015 → Nov 2019 | — | Jason Sperry | Completed | No outcome recorded |
| Phase 3 | NCT03136445 | Jun 2015 → Feb 2022 | disease related to hematopoietic stem cell transplant, hematopoietic and lymphoid cell neoplasm, hemorrhagic disease | NHS Blood and Transplant | Completed | No outcome recorded |
| Phase 3 | NCT03469947 | Mar 2015 → Jul 2024 | — | Arrowhead Regional Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT02302456 | Feb 2015 → Jan 2017 | pregnancy disorder | University Hospital, Angers | Completed | No outcome recorded |
| Phase 3 | NCT02546648 | Feb → Oct 2015 | atherosclerosis | McMaster University | Completed | No outcome recorded |
| Phase 3 | NCT02261415 | Nov 2014 → Aug 2022 overdue | cancer | Sunnybrook Health Sciences Centre | Active not recruiting | No outcome recorded |
| Phase 3 | NCT02312440 | Oct 2014 → Aug 2015 | — | Shanghai Jiao Tong University School of Medicine | Completed | No outcome recorded |
| Phase 3 | NCT02187120 | Jul 2014 → May 2022 | acquired coagulation factor deficiency | Monash University | Completed | No outcome recorded |
| Phase 3 | NCT02125890 | Jul 2014 → Feb 2020 | abdominal aortic aneurysm | Saskatchewan Health Authority - Regina Area | Completed | No outcome recorded |
| Phase 3 | NCT02393300 | Jul 2014 → May 2015 | — | Shanghai Jiao Tong University School of Medicine | Completed | No outcome recorded |
| Phase 3 | NCT01651182 | Mar 2014 → Feb 2015 | cancer | Sunnybrook Health Sciences Centre | Completed | No outcome recorded |
| Phase 3 | NCT02003313 | Nov 2013 → May 2015 | meningitis | Beijing Minhai Biotechnology Co., Ltd | Completed | No outcome recorded |
| Phase 3 | NCT01658124 | Jul 2013 → Jul 2019 | — | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT01727843 | Apr 2013 → Nov 2017 | — | Dr. Jeff Yach | Terminated | No outcome recorded |
| Phase 3 | NCT02153593 | Mar 2013 → Mar 2015 | bone neoplasm | Sant Pau Research Institute | Terminated | No outcome recorded |
| Phase 3 | NCT02150720 | Feb 2013 → Apr 2015 | — | Sant Pau Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT01713101 | Oct 2012 → Jul 2015 | — | Seoul National University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT01655927 | Jul 2012 → Jul 2013 | brain astrocytoma, meningioma | Colombian Foundation for Epilepsy and Neurological Disease | Unknown | No outcome recorded |
| Phase 3 | NCT01402882 | Jul 2012 → Oct 2019 | traumatic brain injury | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT01594671 | Feb → Oct 2012 | — | Sant Pau Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT01519245 | Dec 2011 → Apr 2012 | coronary artery disorder | University of Saskatchewan | Completed | No outcome recorded |
| Phase 3 | NCT01199627 | Mar 2011 → Feb 2013 | — | Basque Health Service | Completed | No outcome recorded |
| Phase 3 | NCT01306370 | Jun 2010 → Oct 2011 | arthropathy | Sant Pau Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT01094977 | Jan 2010 → Jan 2020 | craniosynostosis | The Hospital for Sick Children | Suspended | No outcome recorded |
| Phase 3 | NCT02655653 | Oct 2008 → Oct 2010 | hemorrhagic disease | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT00657384 | Aug 2008 → Aug 2013 | — | University Hospital, Strasbourg, France | Terminated | No outcome recorded |
| Phase 3 | NCT01280981 | Apr 2007 → May 2009 | menstrual disorder | Ferring Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00401193 | Nov 2006 → May 2008 | menstrual disorder | Ferring Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00386308 | Oct 2006 → May 2008 | menstrual disorder | Ferring Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00355108 | Sep 2006 → May 2010 | hereditary hemorrhagic telangiectasia | Hospices Civils de Lyon | Completed | No outcome recorded |
| Phase 3 | NCT00308880 | Mar 2006 → Mar 2007 | head and neck neoplasm | Taichung Veterans General Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT00113568 | Jun 2005 → May 2009 | menstrual disorder | Ferring Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00375258 | May 2005 → Feb 2010 | hemorrhagic disease | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00147862 | May 2005 → Jan 2007 | head and neck neoplasm | Tata Memorial Hospital | Completed | No outcome recorded |
| Phase 3 | NCT00396760 | Jan 2005 → Jul 2006 | aortic valve disorder | German Heart Center | Unknown | No outcome recorded |
| Phase 3 | NCT01031992 | Mar → Aug 2002 | hereditary hemorrhagic telangiectasia | University Hospital, Saarland | Completed | No outcome recorded |
| Phase 4137 trials | ||||||
| Phase 4 | NCT07685743 | Sep 2026 → Mar 2028 expected | osteoarthritis, hip, osteoarthritis, knee | Oregon Health and Science University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07644923 | Aug 2026 → Aug 2028 expected | — | NYU Langone Health | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07696806 | Jul 2026 → Jun 2027 expected | hyperpigmentation of the skin | Sameh Sarsik | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT06832878 | Jun 2026 overdue | — | Mayo Clinic | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07614087 | May → Jun 2026 overdue | osteoarthritis | Hua Luo | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07501884 | May → Dec 2026 expected | urethral stricture | Amjad Alwaal, MD, MSc, FRCSC, FACS | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07115056 | Apr 2026 → Dec 2028 | — | Campbell Clinic | Withdrawn | No outcome recorded |
| Phase 4 | NCT07460518 | Mar → Jun 2026 overdue | anemia, benign prostatic hyperplasia | Hamza Najout | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07116395 | Jan 2026 → Jun 2029 expected | — | Arbi Nazarian, MD | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07314424 | Jan 2026 → Oct 2027 expected | anemia | Tang Xiaodong | Not yet recruiting | No outcome recorded |
| Show all 137 trials opens the full record — a long page | ||||||
| Phase not applicable112 trials | ||||||
| — | NCT07530016 | Aug 2026 → Dec 2027 expected | hyperpigmentation of the skin | The First Affiliated Hospital of Xinxiang Medical College | Not yet recruiting | No outcome recorded |
| — | NCT07714473 | Aug → Nov 2026 expected | rotator cuff syndrome | Hua Luo | Not yet recruiting | No outcome recorded |
| — | NCT07679139 | Jul 2026 → Dec 2027 expected | — | National Cheng-Kung University Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07581457 | Jun 2026 → May 2027 expected | adolescent idiopathic scoliosis | Poznan University of Medical Sciences | Recruiting | No outcome recorded |
| — | NCT07494032 | May 2026 → May 2029 expected | arthropathy | NYU Langone Health | Not yet recruiting | No outcome recorded |
| — | NCT07540026 | May 2026 → Dec 2027 expected | upper digestive tract disorder | National Cheng-Kung University Hospital | Recruiting | No outcome recorded |
| — | NCT07432737 | Feb 2026 → May 2027 expected | bone disorder | University Hospital for Surgical Diseases St. Naum Ohridsk i- Skopje | Recruiting | No outcome recorded |
| — | NCT07390799 | Feb → Aug 2026 overdue | — | Ege University | Not yet recruiting | No outcome recorded |
| — | NCT07318467 | Jan → Jun 2026 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT07401394 | Dec 2025 → Jun 2026 overdue | hemorrhagic disease | Santa Maria Hospital - GVM Care & Research | Active not recruiting | No outcome recorded |
| Show all 112 trials opens the full record — a long page | ||||||
Also used as a comparator or background therapy in 248 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 06 trials | ||||||
| Phase 0 | NCT07280234 Comparator | Nov 2024 → May 2025 | hyperpigmentation of the skin | Hayat Abad Medical Complex, Peshawar | Completed | No outcome recorded |
| Phase 0 | NCT06509256 Comparator | Jul 2024 overdue | urticaria | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT06149091 Comparator | Dec 2023 → Dec 2024 | bronchial disorder | China-Japan Friendship Hospital | Unknown | No outcome recorded |
| Phase 0 | NCT06457360 Comparator | Nov 2023 → Jan 2024 | cirrhosis of liver | British University In Egypt | Completed | No outcome recorded |
| Phase 0 | NCT05427513 Comparator | Apr 2022 → Dec 2023 | — | Shaukat Khanum Memorial Cancer Hospital & Research Centre | Unknown | No outcome recorded |
| Phase 0 | NCT04549012 Comparator | Sep 2020 → Sep 2021 | — | Ain Shams University | Unknown | No outcome recorded |
| Phase 17 trials | ||||||
| Phase 1 | NCT07002749 Comparator | Jun 2025 overdue | — | Patel Hospital, Pakistan | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT05884151 Comparator | Nov 2022 → Apr 2023 | hyperpigmentation of the skin | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
| Phase 1 | NCT05887219 Comparator | Nov 2022 → Apr 2023 | hyperpigmentation of the skin | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
| Phase 1 | NCT06920264 Comparator | Jul 2021 → Sep 2024 | — | St. Louis Joint Replacement Institute | Completed | No outcome recorded |
| Phase 1 | NCT05362500 Comparator | Jun → Nov 2021 | hyperpigmentation of the skin | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
| Phase 1 | NCT03885895 Comparator | Jan → Aug 2019 | — | Kasr El Aini Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT02286973 Comparator | Nov 2014 → Apr 2015 | osteoarthritis | Seoul National University Hospital | Unknown | No outcome recorded |
| Phase 1/26 trials | ||||||
| Phase 1/2 | NCT06330935 Comparator | Mar 2024 → Mar 2025 | traumatic brain injury | Mansoura University | Unknown | No outcome recorded |
| Phase 1/2 | NCT04656067 Comparator | Apr → Oct 2020 | — | Egymedicalpedia | Completed | No outcome recorded |
| Phase 1/2 | NCT04707950 Comparator | Jan 2020 → Feb 2021 | — | Benha University | Unknown | No outcome recorded |
| Phase 1/2 | NCT03780894 Background | Nov 2018 → Jan 2021 | — | Blood and Tissue Bank of Catalonia | Completed | No outcome recorded |
| Phase 1/2 | NCT02616731 Comparator | Sep 2015 → Jan 2016 | menstrual disorder | Ain Shams University | Unknown | No outcome recorded |
| Phase 1/2 | NCT01813058 Comparator | Jan 2013 → May 2016 | adolescent idiopathic scoliosis | Boston Children's Hospital | Completed | No outcome recorded |
| Phase 222 trials | ||||||
| Phase 2 | NCT07127042 Comparator | Aug 2025 → Dec 2026 expected | — | ScinnoHub Pharmaceutical Co., Ltd. | Recruiting | No outcome recorded |
| Phase 2 | NCT07169383 Comparator | Jun → Dec 2025 overdue | hyperpigmentation of the skin | Hina Malik | Enrolling by invitation | No outcome recorded |
| Phase 2 | NCT07392034 Comparator | Jan → Jun 2025 | — | Nishtar Medical University | Completed | No outcome recorded |
| Phase 2 | NCT06479161 Comparator | Jun 2024 → Feb 2025 overdue | — | Matthew Grosso, MD | Recruiting | No outcome recorded |
| Phase 2 | NCT05909072 Comparator | Jun → Nov 2023 | hyperpigmentation of the skin | Zagazig University | Unknown | No outcome recorded |
| Phase 2 | NCT04651166 Comparator | Feb 2022 → Jul 2023 | hemorrhagic disease | University of Hawaii | Completed | No outcome recorded |
| Phase 2 | NCT04272606 Comparator | Aug 2020 → Jun 2023 | intervertebral disk degenerative disorder | Catherine R. Olinger | Completed | No outcome recorded |
| Phase 2 | NCT04187014 Comparator | Feb 2020 → Apr 2021 | — | Carlos A Acosta-Olivo | Completed | No outcome recorded |
| Phase 2 | NCT04117243 Comparator | Jan → Dec 2020 | — | Cairo University | Completed | No outcome recorded |
| Phase 2 | NCT03182751 Comparator | Apr 2018 → May 2022 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 2 | NCT03385928 Comparator | Mar 2018 → May 2023 | intracerebral hemorrhage | Neuroscience Trials Australia | Completed | No outcome recorded |
| Phase 2 | NCT03365999 Comparator | Oct 2017 → Jul 2019 | osteoarthritis, knee, thrombotic disease | Autonomous University of Nuevo León | Completed | No outcome recorded |
| Phase 2 | NCT03112135 Comparator | Apr 2017 → Jan 2018 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2 | NCT02922582 Comparator | Oct 2016 → Nov 2017 | — | Pacira Pharmaceuticals, Inc | Terminated | No outcome recorded |
| Phase 2 | NCT02625948 Comparator | Sep 2015 → Dec 2018 | intracerebral hemorrhage | Ministry of Science and Technology of the People´s Republic of China | Unknown | No outcome recorded |
| Phase 2 | NCT02678208 Comparator | Feb → Jul 2015 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT01940692 Comparator | Jul 2014 → Nov 2015 | osteoarthritis | Ziekenhuis Oost-Limburg | Completed | No outcome recorded |
| Phase 2 | NCT03251469 Comparator | Jan 2013 → Dec 2017 | — | National and Kapodistrian University of Athens | Unknown | No outcome recorded |
| Phase 2 | NCT01702636 Comparator | Dec 2012 → Aug 2019 | intracerebral hemorrhage | Neuroscience Trials Australia | Completed | No outcome recorded |
| Phase 2 | NCT01530399 Comparator | Mar → Nov 2012 | hemorrhagic disease | The Medicines Company | Terminated | No outcome recorded |
| Phase 2 | NCT01408030 Comparator | Aug 2011 → Sep 2014 | hereditary hemorrhagic telangiectasia | James Gossage | Completed | No outcome recorded |
| Phase 2 | NCT03244423 Comparator | Jan 2009 → Aug 2017 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/311 trials | ||||||
| Phase 2/3 | NCT07448415 Comparator | Feb 2026 → Feb 2027 expected | hyperpigmentation of the skin | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT07245264 Comparator | Dec 2025 → Nov 2028 expected | — | St. Olavs Hospital | Recruiting | No outcome recorded |
| Phase 2/3 | NCT07125508 Comparator | Aug 2023 → Sep 2024 | anemia, angiodysplasia of intestine | Louisiana State University Health Sciences Center in New Orleans | Completed | No outcome recorded |
| Phase 2/3 | NCT04742205 Comparator | Feb 2021 → Dec 2023 | intracerebral hemorrhage | Kathmandu Medical College and Teaching Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT04562610 Comparator | Nov 2020 → Oct 2024 | vertebral column disorder | University of California, Davis | Completed | No outcome recorded |
| Phase 2/3 | NCT02314988 Comparator | Jun 2020 → Jul 2027 expected | spinal cord injury | Columbia University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04055194 Comparator | Aug 2019 → Jul 2020 | placenta praevia | Ain Shams University | Unknown | No outcome recorded |
| Phase 2/3 | NCT03856164 Comparator | Jun 2019 → Jan 2020 | hemorrhagic disease | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| Phase 2/3 | NCT02043132 Comparator | Sep 2013 → Dec 2015 | arthropathy | Corewell Health East | Completed | No outcome recorded |
| Phase 2/3 | NCT02684812 Comparator | Jul 2012 → Jul 2019 | subarachnoid hemorrhage | Academic Medical Center - University of Amsterdam | Completed | No outcome recorded |
| Phase 2/3 | NCT01651806 Comparator | May 2012 → Mar 2015 | osteoarthritis | Rush University Medical Center | Completed | No outcome recorded |
| Phase 342 trials | ||||||
| Phase 3 | NCT05713630 Comparator | May 2026 → Mar 2027 expected | — | Unity Health Toronto | Recruiting | No outcome recorded |
| Phase 3 | NCT06622564 Comparator | Jan 2025 → Jan 2026 overdue | epilepsy, hemorrhagic disease | Hamilton Health Sciences Corporation | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT05470816 Comparator | Nov 2022 → Aug 2026 overdue | dementia | Bayside Health | Active not recruiting | No outcome recorded |
| Phase 3 | NCT05648656 Comparator | Feb 2022 → Jan 2023 | — | Post Graduate Institute of Medical Education and Research, Chandigarh | Unknown | No outcome recorded |
| Phase 3 | NCT04344860 Comparator | Jun 2021 → Aug 2024 | von Willebrand disease (hereditary or acquired) | Nicoletta C Machin | Completed | No outcome recorded |
| Phase 3 | NCT04521881 Comparator | Apr 2021 → Dec 2026 expected | traumatic brain injury | London School of Hygiene and Tropical Medicine | Recruiting | No outcome recorded |
| Phase 3 | NCT04788121 Comparator | Nov 2020 → Jun 2021 | — | Post Graduate Institute of Medical Education and Research, Chandigarh | Unknown | No outcome recorded |
| Phase 3 | NCT03923959 Comparator | Feb 2020 → Dec 2022 | — | Lancaster General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT03954314 Comparator | Sep 2019 → Nov 2023 | epilepsy, hemorrhagic disease | Population Health Research Institute | Terminated | No outcome recorded |
| Phase 3 | NCT05518279 Comparator | Sep 2019 → Aug 2021 | bone disorder | Henry Ford Health System | Withdrawn | No outcome recorded |
| Phase 3 | NCT03475342 Comparator | Aug 2019 → Sep 2023 | — | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT03965767 Comparator | Apr → Aug 2019 | chronic rhinosinusitis, nasal cavity polyp | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT02606045 Comparator | Feb 2019 → Apr 2022 | von Willebrand disease (hereditary or acquired) | Margaret Ragni | Terminated | No outcome recorded |
| Phase 3 | NCT02329756 Comparator | Dec 2018 → Dec 2020 | placenta accreta | Baylor College of Medicine | Withdrawn | No outcome recorded |
| Phase 3 | NCT04111822 Background | Oct 2018 → Oct 2020 | infectious disease with sepsis | Cristina Martinez | Completed | No outcome recorded |
| Phase 3 | NCT04149171 Comparator | Sep 2018 → Dec 2020 | — | Cristina Martinez | Completed | No outcome recorded |
| Phase 3 | NCT03505723 Comparator | Jun 2018 → Nov 2021 | thrombotic disease, venous thromboembolism | Population Health Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT03582293 Comparator | Jun 2018 → Apr 2029 expected | — | Academic Medical Center - University of Amsterdam | Recruiting | No outcome recorded |
| Phase 3 | NCT03085394 Comparator | Sep 2017 → Nov 2022 | nervous system injury | Sheba Medical Center | Terminated | No outcome recorded |
| Phase 3 | NCT03122782 Comparator | Aug 2017 | leiomyoma | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT03139422 Comparator | Jul 2017 → Oct 2018 | menstrual disorder | Assiut University | Unknown | No outcome recorded |
| Phase 3 | NCT03044184 Comparator | Apr 2017 → Jun 2020 | intracerebral hemorrhage | Kwong Wah Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT02578901 Comparator | Jun 2016 → Mar 2020 | thrombocytopenia | University of Washington | Completed | No outcome recorded |
| Phase 3 | NCT03751163 Comparator | Mar 2016 → Apr 2017 | hyperpigmentation of the skin | Faculty of Medicine, University of Indonesia | Completed | No outcome recorded |
| Phase 3 | NCT03060889 Comparator | Feb → Nov 2016 | placenta praevia | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT02702128 Comparator | Jan 2016 → Jun 2018 | — | University Hospital, Lille | Completed | No outcome recorded |
| Phase 3 | NCT02587845 Comparator | Oct 2015 → Dec 2016 | hemorrhagic disease | Samsung Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT02492087 Comparator | Aug 2015 → Dec 2016 | — | Dr Meng-Li Lee | Unknown | No outcome recorded |
| Phase 3 | NCT02733952 Comparator | Aug 2015 → Aug 2017 | — | Ain Shams Maternity Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT02438566 Comparator | Apr 2015 → Apr 2016 | osteoarthritis | The New England Baptist Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT01881568 Comparator | Jan 2013 → Jan 2014 | — | Hospital Universitario La Paz | Completed | No outcome recorded |
| Phase 3 | NCT02684851 Comparator | Oct 2012 → Jul 2016 | — | Wake Forest University Health Sciences | Completed | No outcome recorded |
| Phase 3 | NCT01496196 Comparator | Jan 2012 → Jan 2016 | — | Meir Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT01167764 Comparator | Jul 2011 → Jul 2013 | — | Seoul National University Hospital | Withdrawn | No outcome recorded |
| Phase 3 | NCT01338454 Comparator | Mar → Aug 2011 | obstetric disorder | Erzincan Military Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02781597 Comparator | Jan 2011 → Jun 2012 | — | Post Graduate Institute of Medical Education and Research, Chandigarh | Completed | No outcome recorded |
| Phase 3 | NCT00872469 Comparator | May 2009 → Jun 2016 | — | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00755209 Comparator | Oct 2008 → Oct 2009 | traumatic brain injury | Khon Kaen University | Completed | No outcome recorded |
| Phase 3 | NCT00327106 Comparator | Apr 2005 → Feb 2007 | — | University Hospital of Saint-Etienne | Completed | No outcome recorded |
| Phase 3 | NCT00500656 Comparator | Mar 2005 → Jul 2006 | hereditary angioedema | Shire | Completed | No outcome recorded |
| Phase 3 | NCT00588133 Comparator | Jan 2004 → Dec 2007 | cardiac valvular defect | Mayo Clinic | Completed | No outcome recorded |
| Phase 3 | NCT00444470 Comparator | Feb 2003 → May 2007 | — | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 484 trials | ||||||
| Phase 4 | NCT07522788 Comparator | Jun → Nov 2026 expected | hyperpigmentation of the skin | Hayatabad Medical Complex | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06894719 Comparator | Jun → Dec 2026 expected | — | Rush University Medical Center | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07332910 Comparator | Jan → Jun 2026 overdue | hemarthrosis | Chirec | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07078942 Comparator | Jul 2025 → Jul 2026 overdue | — | Chulalongkorn University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07089251 Comparator | Jul 2025 → Jun 2027 expected | osteoarthritis, knee | King Abdullah International Medical Research Center | Recruiting | No outcome recorded |
| Phase 4 | NCT06820177 Comparator | Apr 2025 → May 2027 expected | hemorrhagic disease | University of California, San Diego | Recruiting | No outcome recorded |
| Phase 4 | NCT06777966 Comparator | Jan → Jun 2025 overdue | — | Cairo University | Recruiting | No outcome recorded |
| Phase 4 | NCT07034560 Comparator | Nov 2024 → Nov 2025 overdue | hyperpigmentation of the skin | Thammasat University | Active not recruiting | No outcome recorded |
| Phase 4 | NCT06270407 Comparator | Oct 2024 → Dec 2028 expected | — | St. Olavs Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT06356948 Comparator | Mar 2024 → Jul 2027 expected | — | University of British Columbia | Recruiting | No outcome recorded |
| Phase 4 | NCT06109155 Comparator | Feb 2024 → Dec 2026 expected | cardiac valvular defect | Taichung Veterans General Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07455591 Background | Jan → Aug 2024 | osteoarthritis, knee | Singapore General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT06128330 Comparator | Dec 2023 → Dec 2025 overdue | — | Insel Gruppe AG, University Hospital Bern | Recruiting | No outcome recorded |
| Phase 4 | NCT06086444 Comparator | Oct 2023 → Oct 2025 | abdominal wall malformation, hemorrhagic disease | Poznan University of Medical Sciences | Completed | No outcome recorded |
| Phase 4 | NCT06025916 Comparator | Sep 2023 → Dec 2025 overdue | — | Karolinska Institutet | Recruiting | No outcome recorded |
| Phase 4 | NCT05945680 Comparator | Sep 2023 → Sep 2025 | hemorrhagic disease | Poznan University of Medical Sciences | Completed | No outcome recorded |
| Phase 4 | NCT06188052 Comparator | Aug 2023 → Jan 2024 | — | Kasr El Aini Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05806307 Comparator | Mar → Oct 2023 | drug pseudoallergy, uterine corpus leiomyoma | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT05686005 Comparator | Dec 2022 → Apr 2023 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 4 | NCT05448456 Comparator | Jul 2022 → Aug 2023 | anemia | Assuta Ashdod Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04192435 Comparator | May 2022 → Sep 2025 | hemorrhagic disease, nosocomial infection, skin infection | Bayside Health | Completed | No outcome recorded |
| Phase 4 | NCT05340205 Comparator | May → Dec 2022 | placenta praevia | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT05309525 Comparator | Apr → Sep 2022 | — | Luxurgery | Completed | No outcome recorded |
| Phase 4 | NCT05504577 Background | Mar 2022 → Jul 2023 | arthropathy | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04803747 Comparator | Feb 2022 → Mar 2024 | — | University of Manitoba | Completed | No outcome recorded |
| Phase 4 | NCT06183918 Comparator | Dec 2021 → Dec 2022 | — | Izmir Ataturk Training and Research Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04855877 Comparator | Jul 2021 → Jun 2023 | — | University of Liege | Unknown | No outcome recorded |
| Phase 4 | NCT05326139 Comparator | Jun → Sep 2021 | eyelid disorder | Baskent University | Completed | No outcome recorded |
| Phase 4 | NCT04766996 Background | May → Dec 2021 | substance-related disorder | Emory University | Terminated | No outcome recorded |
| Phase 4 | NCT05705336 Comparator | Jan → Dec 2021 | — | Alejandro Reyes Sánchez | Completed | No outcome recorded |
| Phase 4 | NCT04691362 Comparator | Jan 2021 → Dec 2022 | — | University of Liege | Completed | No outcome recorded |
| Phase 4 | NCT04347122 Comparator | Jan 2020 → Aug 2023 | musculoskeletal system cancer, soft tissue sarcoma | University of Kansas Medical Center | Terminated | No outcome recorded |
| Phase 4 | NCT03789422 Comparator | Dec 2019 → Sep 2022 | chronic urticaria | University Hospital, Grenoble | Unknown | No outcome recorded |
| Phase 4 | NCT04443920 Comparator | Oct 2019 → Oct 2020 | — | The Miriam Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03899233 Comparator | Apr → Oct 2019 | hyperpigmentation of the skin | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT04085575 Comparator | Jan → Dec 2019 | — | Centre Hospitalier de Montauban | Completed | No outcome recorded |
| Phase 4 | NCT03710330 Comparator | Nov 2018 → Mar 2020 | — | Aswan University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03623789 Comparator | Aug 2018 → Jul 2020 | — | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03606785 Comparator | Aug 2018 → Jan 2020 | colorectal cancer | Assiut University | Completed | No outcome recorded |
| Phase 4 | NCT03606109 Comparator | Jun 2018 → Jun 2021 | — | NYU Langone Health | Completed | No outcome recorded |
| Phase 4 | NCT03631355 Comparator | Jun 2018 → Mar 2020 | — | NYU Langone Health | Completed | No outcome recorded |
| Phase 4 | NCT03360045 Comparator | May → Aug 2018 | — | Kecioren Education and Training Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03653429 Comparator | Mar → Dec 2018 | toe, misshapen | Icahn School of Medicine at Mount Sinai | Completed | No outcome recorded |
| Phase 4 | NCT03211286 Comparator | Jan 2018 → Mar 2021 | anemia | Alejandro Lizaur-Utrilla, PhD, MD | Completed | No outcome recorded |
| Phase 4 | NCT03376061 Comparator | Dec 2017 → Sep 2018 | hemorrhagic disease | Population Health Research Institute | Completed | No outcome recorded |
| Phase 4 | NCT03317795 Comparator | Nov 2017 → Dec 2020 | benign neoplasm of corpus uteri, menstrual disorder | Shannon K. Laughlin-Tommaso | Completed | No outcome recorded |
| Phase 4 | NCT03310060 Comparator | Nov 2017 → Aug 2018 | — | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03328832 Comparator | Sep 2017 → Sep 2018 | osteoarthritis, knee | Chang Gung Memorial Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03023189 Comparator | Apr 2017 → Apr 2019 | cirrhosis of liver | Assistance Publique - Hôpitaux de Paris | Unknown | No outcome recorded |
| Phase 4 | NCT04986813 Comparator | Apr 2017 → Aug 2018 | — | Jaspreet Singh | Completed | No outcome recorded |
| Phase 4 | NCT03070847 Comparator | Mar 2017 → Mar 2019 | — | Bartłomiej Wódarski | Unknown | No outcome recorded |
| Phase 4 | NCT03037515 Comparator | Feb 2017 → Jun 2018 | anemia | Henry Ford Health System | Completed | No outcome recorded |
| Phase 4 | NCT02938962 Comparator | Oct 2016 → Nov 2018 | — | Mount Sinai Hospital, Canada | Unknown | No outcome recorded |
| Phase 4 | NCT02865174 Comparator | Sep 2016 → Aug 2017 | osteoarthritis, knee | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02903017 Comparator | Sep 2016 → Mar 2018 | — | Kocaeli University | Completed | No outcome recorded |
| Phase 4 | NCT02739815 Comparator | Apr → Jun 2016 | — | Talkha Central Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02656472 Comparator | Feb 2016 → Apr 2017 | — | Wake Forest University Health Sciences | Completed | No outcome recorded |
| Phase 4 | NCT02615366 Comparator | Feb 2016 → Feb 2019 | — | Ottawa Hospital Research Institute | Unknown | No outcome recorded |
| Phase 4 | NCT02825719 Background | Dec 2015 → Mar 2020 | leiomyoma | Queen Mary Hospital, Hong Kong | Terminated | No outcome recorded |
| Phase 4 | NCT01940536 Comparator | Dec 2015 → Dec 2018 | — | Hospital for Special Surgery, New York | Withdrawn | No outcome recorded |
| Phase 4 | NCT02540226 Comparator | Nov 2015 → Dec 2018 | osteoarthritis, knee | Hospital for Special Surgery, New York | Completed | No outcome recorded |
| Phase 4 | NCT02453802 Comparator | Jun 2015 → May 2016 | osteoarthritis, knee | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02580227 Comparator | Jun 2015 → Aug 2016 | bone disorder | Good Samaritan Regional Medical Center, Oregon | Unknown | No outcome recorded |
| Phase 4 | NCT02354885 Comparator | Dec 2014 → Dec 2015 | hemorrhagic disease | University of Zurich | Unknown | No outcome recorded |
| Phase 4 | NCT02122679 Comparator | Dec 2014 → Jun 2015 | congenital heart disease | Emory University | Withdrawn | No outcome recorded |
| Phase 4 | NCT02584725 Comparator | Dec 2014 → Jun 2015 | arthropathy | Columbia University | Completed | No outcome recorded |
| Phase 4 | NCT02279186 Comparator | Sep 2014 → Mar 2015 | hemorrhagic disease | Ain Shams Maternity Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02229292 Comparator | Aug 2014 → Sep 2016 | — | Esbjerg Hospital - University Hospital of Southern Denmark | Completed | No outcome recorded |
| Phase 4 | NCT02252497 Comparator | Apr 2014 → Jan 2016 | — | University Hospital of Saint-Etienne | Completed | No outcome recorded |
| Phase 4 | NCT02094066 Comparator | Mar → Jun 2014 | hemorrhagic disease | TC Erciyes University | Unknown | No outcome recorded |
| Phase 4 | NCT02152917 Comparator | Feb 2014 → Feb 2015 | osteoarthritis, knee | University of Sao Paulo General Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01873768 Comparator | Jan 2014 → Dec 2015 | osteoarthritis | Miller Orthopedic Specialists | Completed | No outcome recorded |
| Phase 4 | NCT02427412 Comparator | Jan 2014 → May 2015 | venous thromboembolism | Hvidovre University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01940523 Comparator | May 2013 → Dec 2015 | osteoarthritis | Hospital for Special Surgery, New York | Completed | No outcome recorded |
| Phase 4 | NCT01940419 Comparator | Apr 2013 → Nov 2014 | — | Hillerod Hospital, Denmark | Completed | No outcome recorded |
| Phase 4 | NCT01714336 Comparator | Sep 2012 → Oct 2015 | bone disorder | Mayo Clinic | Completed | No outcome recorded |
| Phase 4 | NCT02458729 Comparator | Aug 2012 → Jul 2014 | osteoarthritis, knee | Chang Gung Memorial Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01643135 Comparator | Jun 2012 → Dec 2013 | hemorrhagic disease | Mahidol University | Completed | No outcome recorded |
| Phase 4 | NCT01622946 Comparator | Apr 2012 → Apr 2020 | — | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| Phase 4 | NCT01800435 Comparator | Oct 2011 → Oct 2012 | hemophilia A | Oslo University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02374398 Comparator | Mar 2011 → Nov 2014 | — | Eastern Maine Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02747615 Comparator | Aug 2010 → Oct 2013 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 4 | NCT01228136 Comparator | Jan → Nov 2010 | adenoid hypertrophy | Irmandade Santa Casa de Misericórdia de Porto Alegre | Completed | No outcome recorded |
| Phase 4 | NCT00740116 Comparator | Mar 2008 → Jun 2012 | ovarian cancer | Preben Kjolhede, MD, professor | Completed | No outcome recorded |
| Phase not applicable70 trials | ||||||
| — | NCT07495748 Comparator | Jul → Dec 2026 expected | hyperpigmentation of the skin | Foundation University Islamabad | Not yet recruiting | No outcome recorded |
| — | NCT07540702 Comparator | Feb → Aug 2026 overdue | hyperpigmentation of the skin | Kasr El Aini Hospital | Recruiting | No outcome recorded |
| — | NCT07365150 Comparator | Jan 2026 → Jun 2027 expected | intracerebral hemorrhage | The University of Hong Kong | Recruiting | No outcome recorded |
| — | NCT07192640 Comparator | Oct 2025 → Feb 2026 overdue | hemorrhagic disease, obesity disorder | Ain Shams University | Not yet recruiting | No outcome recorded |
| — | NCT06208267 Comparator | Aug 2025 → Apr 2027 expected | esophageal varices with bleeding | St. Mary's Research Center, Canada | Recruiting | No outcome recorded |
| — | NCT04811313 Comparator | Apr 2025 → Jan 2026 overdue | musculoskeletal system disorder | Assiut University | Recruiting | No outcome recorded |
| — | NCT06763094 Comparator | Jan → Nov 2025 overdue | menstrual disorder, uterine anomalies | University of Health Sciences Lahore | Not yet recruiting | No outcome recorded |
| — | NCT06434636 Comparator | Dec 2024 → May 2025 | middle ear disorder | TC Erciyes University | Completed | No outcome recorded |
| — | NCT06604325 Comparator | Oct 2024 → Mar 2025 overdue | — | Aligarh Muslim University | Recruiting | No outcome recorded |
| — | NCT07610863 Comparator | Jun 2024 → Jul 2025 | — | St. Anne's University Hospital Brno, Czech Republic | Completed | No outcome recorded |
| — | NCT06522984 Comparator | Jun 2024 → Jun 2025 | skin pigmentation disorder | Egymedicalpedia | Unknown | No outcome recorded |
| — | NCT06435832 Comparator | May 2024 | alveolar periostitis | Recep Tayyip Erdogan University | Unknown | No outcome recorded |
| — | NCT06369012 Comparator | Mar → Sep 2024 | uterine anomalies | Egymedicalpedia | Completed | No outcome recorded |
| — | NCT06243575 Background | Feb → Mar 2024 | neuropathy, painful | Department of Medical Services Ministry of Public Health of Thailand | Unknown | No outcome recorded |
| — | NCT06587620 Comparator | Dec 2023 → Jun 2024 | — | Zagazig University | Completed | No outcome recorded |
| — | NCT07288697 Comparator | Nov 2023 → Apr 2024 | spinal cord disorder, vertebral column disorder | Dr. Lutfi Kirdar Kartal Training and Research Hospital | Completed | No outcome recorded |
| — | NCT06091891 Comparator | Oct 2023 → Aug 2025 | scoliosis | Seoul National University Hospital | Unknown | No outcome recorded |
| — | NCT06060327 Comparator | Oct 2023 → Jun 2024 | — | Cairo University | Completed | No outcome recorded |
| — | NCT05841251 Comparator | May → Sep 2023 | — | Assiut University | Unknown | No outcome recorded |
| — | NCT05759156 Comparator | Mar 2023 → Feb 2024 | — | Dow University of Health Sciences | Completed | No outcome recorded |
| — | NCT05921071 Comparator | Jan 2023 → Jun 2024 | — | Wolfson Medical Center | Unknown | No outcome recorded |
| — | NCT05840471 Comparator | Jan 2023 → Feb 2024 | — | Hawler Medical University | Completed | No outcome recorded |
| — | NCT05688111 Comparator | Dec 2022 → Dec 2023 | placenta praevia | Hawler Medical University | Completed | No outcome recorded |
| — | NCT05517590 Comparator | Sep 2022 → Apr 2024 | uterine corpus leiomyoma | Acibadem University | Completed | No outcome recorded |
| — | NCT05230381 Comparator | Jun 2022 → Dec 2024 | meningioma | Beijing Tiantan Hospital | Unknown | No outcome recorded |
| — | NCT05273632 Comparator | Mar → Sep 2022 | — | Egymedicalpedia | Completed | No outcome recorded |
| — | NCT06301204 Comparator | Mar 2022 → Nov 2023 | hemorrhagic disease | Bezmialem Vakif University | Completed | No outcome recorded |
| — | NCT04996368 Comparator | Feb → May 2022 | substance abuse | Shahid Gangalal National Heart Centre | Completed | No outcome recorded |
| — | NCT04694677 Comparator | Jan → Aug 2021 | leiomyoma | Aljazeera Hospital | Unknown | No outcome recorded |
| — | NCT04622397 Comparator | Jan → Nov 2021 | scoliosis | Cairo University | Unknown | No outcome recorded |
| — | NCT04696224 Comparator | Dec 2020 → Dec 2022 | hemorrhagic disease | Universidade do Vale do Sapucai | Unknown | No outcome recorded |
| — | NCT04595786 Comparator | Oct 2020 → Jan 2024 | epilepsy, meningioma | Beijing Tiantan Hospital | Completed | No outcome recorded |
| — | NCT04419246 Comparator | Jul 2020 | peripheral nerve lesion | Bursa Yuksek Ihtisas Training and Research Hospital | Unknown | No outcome recorded |
| — | NCT04463966 Comparator | Apr 2020 → Apr 2021 | — | Benha University | Unknown | No outcome recorded |
| — | NCT04350645 Comparator | Mar 2020 → Dec 2021 | placenta praevia | Universiti Kebangsaan Malaysia Medical Centre | Unknown | No outcome recorded |
| — | NCT04201951 Comparator | Feb → Oct 2020 | — | Hawler Medical University | Completed | No outcome recorded |
| — | NCT04188184 Comparator | Dec 2019 → Apr 2020 | esophageal varices with bleeding | Assiut University | Completed | No outcome recorded |
| — | NCT04367155 Comparator | Sep 2019 → Sep 2021 | nephrolithiasis | Kafrelsheikh University | Unknown | No outcome recorded |
| — | NCT03870256 Comparator | Apr 2019 → Aug 2021 | — | Aswan University Hospital | Completed | No outcome recorded |
| — | NCT03880604 Comparator | Apr 2019 → Mar 2021 | leiomyoma | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT03880045 Comparator | Apr 2019 → Mar 2021 | leiomyoma | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT05594186 Comparator | Mar 2019 → Oct 2022 | — | Saudi German Hospital - Madinah | Completed | No outcome recorded |
| — | NCT03820206 Comparator | Jan → Nov 2019 | — | Cairo University | Completed | No outcome recorded |
| — | NCT03774706 Comparator | Jan 2019 → Dec 2021 | — | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT03777878 Comparator | Jan 2019 → Mar 2021 | — | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT03774524 Comparator | Jan 2019 → Dec 2020 | — | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT03777696 Comparator | Jan 2019 → Dec 2020 | — | hany farouk | Unknown | No outcome recorded |
| — | NCT03778242 Comparator | Jan 2019 → Mar 2022 | — | Aswan University Hospital | Completed | No outcome recorded |
| — | NCT03741114 Comparator | Dec 2018 → Nov 2020 | placenta praevia | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT03710304 Comparator | Nov 2018 → Mar 2020 | — | Aswan University Hospital | Completed | No outcome recorded |
| — | NCT03706339 Comparator | Nov 2018 → Mar 2020 | — | Aswan University Hospital | Completed | No outcome recorded |
| — | NCT03646474 Comparator | Aug 2018 → Jan 2020 | — | Assiut University | Completed | No outcome recorded |
| — | NCT03570710 Comparator | Jan 2018 → Jun 2021 | — | Aswan University Hospital | Completed | No outcome recorded |
| — | NCT03656445 Comparator | Oct 2015 → Mar 2017 | osteoarthritis, knee | Democritus University of Thrace | Completed | No outcome recorded |
| — | NCT02860221 Background | May 2015 → Jul 2017 | — | Southwest Hospital, China | Unknown | No outcome recorded |
| — | NCT02864095 Background | May 2015 → Oct 2017 | — | Southwest Hospital, China | Unknown | No outcome recorded |
| — | NCT02288923 Comparator | Mar 2015 → Jul 2018 | osteoarthritis, knee | Royal Devon and Exeter NHS Foundation Trust | Completed | No outcome recorded |
| — | NCT02233101 Comparator | Jun 2014 → Aug 2015 | — | Rush University Medical Center | Completed | No outcome recorded |
| — | NCT02084342 Background | Dec 2013 → Apr 2014 | idiopathic scoliosis | Liu Weifeng | Unknown | No outcome recorded |
| — | NCT02051686 Comparator | Jun 2013 → Dec 2016 | — | University of Missouri-Columbia | Completed | No outcome recorded |
| — | NCT01527968 Comparator | Apr 2012 → Dec 2016 | osteoarthritis | Heekin Orthopedic Research Institute | Unknown | No outcome recorded |
| — | NCT01538160 Background | Feb 2012 → Jul 2015 | coagulation protein disease | Sheba Medical Center | Unknown | No outcome recorded |
| — | NCT01535781 Comparator | Sep 2011 → Jun 2014 | anemia, bone disorder | Hvidovre University Hospital | Terminated | No outcome recorded |
| — | NCT01428713 Comparator | Aug 2011 → Jun 2013 | menstrual disorder | Baylor College of Medicine | Completed | No outcome recorded |
| — | NCT01600599 Comparator | Jan 2011 → Apr 2012 | — | University of Malaya | Completed | No outcome recorded |
| — | NCT01248104 Comparator | Mar 2010 → Mar 2013 | — | Loma Linda University | Completed | No outcome recorded |
| — | NCT01850394 Comparator | Jan 2010 → Jan 2011 | osteoarthritis, knee | Mahidol University | Completed | No outcome recorded |
| — | NCT01027546 Comparator | Jan 2007 → May 2008 | spinal cord disorder | Yodakubo Hospital | Completed | No outcome recorded |
| — | NCT00994994 Comparator | Jan 2006 → Aug 2007 | congenital heart disease | Okayama University | Completed | No outcome recorded |
| — | NCT02738073 Comparator | ? → Feb 2017 | — | Rothman Institute Orthopaedics | Unknown | No outcome recorded |
Evidence & citations 37 cited values
Every value below carries the sentence it was read from. 770 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tranexamic Acid | “Effects of Co-administered Sublingual Misoprostol and Intravenous Tranexamic Acid on Prevention of Postpartum Hemorrhage in Pregnant Women With Twin Pregnancy Undergoing...” NCT03774524 ↗684“Whole Blood Clot Stability and Thrombin Generating Capacity Following Treatment With Bypassing Agents (BPA) With and Without and Tranexamic Acid (TXA) in Haemophilia A Patients...” NCT01800435 ↗ “The aim of this study is to compare the effectiveness of combined tranexamic acid (TA) and oxytocin infusion with intravenous carbetocin for prevention of PPH in patients with...” NCT03777878 ↗ “OBJECTIVE: To estimate the effects of adding intravenous tranexamic acid (TA) to the standard active management of third-stage labor to reduce vaginal blood loss during the...” PMID 23023559 ↗ Sep 2012 “Tranexamic acid (TXA) has been routinely delivered in multisegmental spinal decompression and bone graft fusion surgeries with satisfactory outcomes in minimizing gross blood...” PMID 30755256 ↗ Feb 2019 “Patients in the experimental group will receive a loading dose of tranexamic acid (TXA) at a concentration of 1g/10ml over a period of 10 minutes, administered immediately...” NCT05794321 ↗ “Group (II): patients received 1 gm tranexamic acid (TA), (2 ampoules of Capron® 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision plus Intrauterine Inflated...” NCT03741114 ↗ “10 mg/kg tranexamic acid (Transamine 10% IV/IM Injectable Solution) will be placed into 100 cc physiological saline through the appropriate vascular access and injected within...” NCT06434636 ↗ “Tranexamic acid will be given as per unit protocol, (currently 1g pre-operatively IV and 500mg orally at 8 hours post op. unless contraindicated by a high risk of thrombosis.)” NCT02288923 ↗ “To determine whether intraoperative tranexamic acid (TXA) administration reduced intraoperative blood loss in patients undergoing large meningioma resection.” PMID 42115323 ↗ May 2026 “Patient will receive an intravenous perfusion of 300 mg Exacyl (tranexamic acid) intravenous (IV) over 9 minutes, starting at the time of surgical incision.” NCT03822793 ↗ “Oral administration of 2 grammes tranexamic acid 2 hours before skin incision and 2 grammes oral tranexamic acid 4 hours after first administration” NCT04855877 ↗ “Tranexamic acid (TXA) is a drug that has proved useful in reducing bleeding associated with other surgeries and CRT results have been positive” NCT01199627 ↗ “Subjects will be given the therapeutic dose of tranexamic acid for menorrhagia, which is 1300 mg PO TID for up to 5 days during menstruation” NCT05309525 ↗ “single dose of 20ug/kg of recombinant factor VIIa along with tranexamic acid of 4 gram a day for 7 days following surgery” NCT01538160 ↗ “Tranexamic acid (Amchafibrin) exerts an antihemorrhagic activity by inhibiting the fibrinolytic properties of plasmin.” NCT03386656 ↗ “These medications are Ofirmev ( acetaminophen ) 1,000mg and tranexamic acid 2,000 mg , an antifibrinolytic drug.” NCT04562610 ↗ “Intravenous and topical tranexamic acid (TXA) have been well established in reducing blood loss postoperatively.” NCT03074994 ↗ “Tranexamic acid (TA) is an antifibrinolytic agent that blocks the lysine-binding site of plasminogen to fibrin.” NCT03870256 ↗ “Tranexamic acid and Etamsylate are slowly given intravenously 10 minutes before start of Cesarean Delivery” NCT05273632 ↗ “Patients randomized to the IV TXA group will receive intravenous Tranexamic acid during the procedure.” NCT07131592 ↗ “Tranexamic acid (TXA) reduces blood loss and transfusion in paediatric craniosynostosis surgery.” PMID 32620262 ↗ Jun 2020 “Tranexamic acid will be used in aconcentration of 4mg/ml ,1ml will be used fo half of the face.” NCT03923062 ↗ “A gauze soaked with 2 g tranexamic acid (20 ml) diluted in 100 ml of sodium chloride0.9%” NCT03880045 ↗ “Tranexamic Acid Versus Placebo to Reduce Perioperative Bleeding After Major Hepatectomy” NCT00657384 ↗ “Topical tranexamic acid (TXA) and ascorbic acid are both effective in treating melasma” NCT07522788 ↗ “0.5g of tranexamic acid is administered locally after dilution before surgical closure” NCT07314424 ↗ “Tranexamic acid (TXA) reduces bleeding and transfusion requirements in established PPH” PMID 36934142 ↗ Mar 2023 “Intravenous tranexamic acid (TXA) reduces bleeding deaths after injury and childbirth.” PMID 33010927 ↗ Sep 2020 “will receive 1 g tranexamic acid (2 ampoules of kapron 500 mg, kapron®, Amoun, Egypt)” NCT05806307 ↗ “Intraosseous injection of Ketorolac 15mg and Tranexamic acid 500mg in femoral canal” NCT06243575 ↗ “2g of sucralfate powder and 1g of tranexamic acid powder will be sprayed after EST” NCT06107504 ↗ “Tranexamic acid (TXA), an antifibrinolytic agent, reduces perioperative bleeding” NCT07288697 ↗ “the use of topical and intravenous (IV) Tranexamic Acid (TXA) in spine surgery.” NCT02093988 ↗ “1.3 mg oral tranexamic acid or 1.0 mg oral estradiol three times a day” NCT01659008 ↗ “tranexamic acid (TXA) nebulization to control bleeding in hemoptysis.” PMID 41221568 ↗ Oct 2025 “1-gram tranexamic acid (10 ml) in 100 ml saline infusion” NCT03880604 ↗ “Tranexamic acid belongs to fibrinolytic inhibitors.” NCT00308880 ↗ “1 gm of tranexamic acid in 100 ml saline iv” NCT03777696 ↗ “Tranexamic acid intravenous administration” NCT05806346 ↗ “Tranexamic acid injection 8-10mg/kg” NCT05957822 ↗ “Tranexamic Acid 500 mg” NCT06369012 ↗ “tranexamic acid(TXA)” NCT05138913 ↗ “Tranexamic Acid” NCT03825939 ↗ |
| Known as | 1,4-amino-carboxylic acid | “1,4-amino-carboxylic acid (tranexamic acid)” PMID 23917458 ↗ Sep 2014 |
| Known as | Acide Tranexamique | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04085575 ↗ |
| Known as | AMCA | “Tranexamic acid (AMCA) is a potent antifibrinolytic drug” PMID 3321402 ↗ 1987 |
| Known as | Amchafibrin | “Tranexamic acid (Amchafibrin) exerts an antihemorrhagic activity by inhibiting the fibrinolytic properties of plasmin.” NCT03386656 ↗ |
| Known as | AXA | “Tranexamic acid (AXA) and aminocaproic acid (EACA) are synthetic drugs derived from Lysine that competitively inhibit the lysine receptors in the plasminogen and plasmin...” NCT03365999 ↗ |
| Known as | Capron | “Group (II): patients received 1 gm tranexamic acid (TA), (2 ampoules of Capron® 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision plus Intrauterine Inflated...” NCT03741114 ↗3“1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision” NCT03706339 ↗ “1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision” NCT03710330 ↗ “1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Amoun, Cairo, Egypt)” NCT03570710 ↗ |
| Known as | Cyclokapron | “Cyclokapron” NCT05323149 ↗ |
| Known as | Cyklo-f | “Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 ↗ 2003 |
| Known as | Cyklokapron | “Patients in the TXA group will be given 15 mg/kg of tranexamic acid (Cyklokapron@; Amoun Pharmaceutical Co., SAE) slowly intravenously 30 min before surgery followed by 10 mg/...” NCT03892668 ↗9“Subjects will be randomized in a 1:1:1:1 ratio to receive either DepoTXA 400 mg, DepoTXA 800 mg, DepoTXA 1200 mg, or IV TXA (Cyklokapron® 1 gram).” NCT02922582 ↗ “Standard surgery using burr-hole procedure, irrigation and drainage combined withTranexamic acid (Cyklokapron) administration.” NCT03353259 ↗ “Tranexamic acid (Cyklokapron) is utilized extensively for menorrhagia in Australia and the United Kingdom.” NCT00111215 ↗ “1 gm of Tranexamic Acid (Cyklokapron) that will be dissolved in 50 ml of injectable 0.9% saline” NCT05913466 ↗ “Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 ↗ 2003 “topical tranexamic acid (TXA - Cyklokapron; Pfizer, New York, NY)” NCT05357079 ↗ “Tranexamic Acid Injection [Cyklokapron]” NCT05464394 ↗ “Tranexamic Acid (Cyklokapron)” NCT07245264 ↗ “Tranexamic Acid (Cyklokapron)” NCT02053363 ↗ |
| Known as | Cyklokapron (tranexamic acid) | “Cyklokapron (tranexamic acid)” NCT01535781 ↗ |
| Known as | EXACYL | “Patient will receive an intravenous perfusion of 300 mg Exacyl (tranexamic acid) intravenous (IV) over 9 minutes, starting at the time of surgical incision.” NCT03822793 ↗7“IV Tranexamic acid (Exacyl®): 1 gram diluted in 20 mL saline solution, in 30 minutes, five minutes before skin incision and a second 1 gram, 3 hours later.” NCT02428868 ↗ “Tranexamic acid (TA) (Exacyl® Sanofi France), an antifibrinolytic drug, reduces bleeding and transfusion need in major surgery and trauma (1).” NCT02797119 ↗ “intravenous administration of 10-mL of tranexamic acid (EXACYL® 1 g/10 ml I.V., solution injectable)” NCT03431805 ↗ “Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 ↗ 2003 “Active comparator : Tranexamic Acid (Exacyl)” NCT02252497 ↗ |
| Known as | Group T | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02003313 ↗ |
| Known as | Kapron | “In Tranexamic group (n=111), patients will be given 1 gm (10 ml) TXA (Kapron, Amoun, Egypt) diluted in 20 ml of Glucose 5% (administered as intravenous infusion over 5 minutes,...” NCT06060327 ↗6“Women assigned to the study group will receive 1 gr of TXA injection (Kapron, AMOUN Pharmaceutical co.) given slowly I.V over 10 minutes before the operation.” NCT02350179 ↗ “Tranexamic acid (Kapron ampoules, 100 mg/mL) is diluted under aseptic conditions to a final concentration of 10 mg/mL” NCT07540702 ↗ “soaked in Tranexamic acid (Kapron, Amoun Pharmaceuticals SAE, Egypt. 5ml Amp, 100mg /1ml)” NCT05439694 ↗ “will receive 1 g tranexamic acid (2 ampoules of kapron 500 mg, kapron®, Amoun, Egypt)” NCT05806307 ↗ “using a sterile towel soaked with 2g tranexamic acid (Kapron, Amoun, Cairo, Egypt)” NCT06515535 ↗ “Tranexamic acid (Kapron, Amoun Pharmaceuticals SAE, Egypt. 5ml Amp, 100mg /1ml)” NCT05434533 ↗ |
| Known as | Kepron | “Tranexamic acid (Kepron, Amoun, Egypt) was given slowly intravenously over 10 minutes just before the skin incision of elective cesarean section to group A.” NCT03351686 ↗ |
| Known as | LB1148 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02836470 ↗ |
| Known as | Lysteda | “Medications: tranexamic acid (Lysteda, Pierre Fabre Mexico) or aminocaproic acid (Amikar, Wyeth), as appropriate, will be administered orally three times (administering 2...” NCT03365999 ↗ |
| Known as | Marcan-Tranexamic Acid | “Marcan-Tranexamic Acid 500 mg oral tablet over-encapsulated to match the placebo.” NCT05713630 ↗ |
| Known as | Sandoz-Tranexamic Acid | “Sandoz-Tranexamic Acid 100 mg/mL solution for injection via intravenous (IV) added to a 100mL infusion bag of NaCl 0.9% and infused by slow intravenous injection over 20 minutes.” NCT05713630 ↗ |
| Known as | TNA | “Tranexamic acid (TNA) is an antifibrinolytic agent that inhibits fibrinolysis by blocking the activation of plasminogen.” NCT07174895 ↗1“Despite the documented blood-saving effects of tranexamic acid (TNA) in total knee arthroplasty (TKA)” PMID 23592025 ↗ Apr 2013 |
| Known as | tnx acid | “group 1 (TRANEXEL 250 mg/5 mL) patients administered 250 mg tnx acid during the whole bimaxillary orthognathic surgery” NCT06301204 ↗ |
| Known as | TRAN | “BACKGROUND: To assess the equivalence of tranexamic acid (TRAN) versus synthetic oxytocin (OXY) in reducing post-partum blood loss, in full-term patients (37-42 weeks), at low...” PMID 38873634 ↗ May 2024 |
| Known as | Tranexam OrPha | “Tranexamic acid 10mg/kg (Tranexam OrPha 1000 mg/10 ml, OrPha Swiss GmbH, Küsnacht, Switzerland) will be administered 15 -30 minutes prior to surgery followed by infusion of...” NCT04625530 ↗ |
| Known as | Tranexamic acid (CYKLOKAPRON) (Pfizer, New York, NY). | “Tranexamic acid (CYKLOKAPRON) (Pfizer, New York, NY).” NCT06419075 ↗ |
| Known as | tranexamic acid (TXA) | “tranexamic acid (TXA)” NCT05639686 ↗ |
| Known as | Tranexamic acid injection | “Drug: Tranexamic acid injection” NCT04622397 ↗1“Drug: Tranexamic acid injection” NCT05236569 ↗ |
| Known as | Tranexamic acid, Cyclokapron | “Tranexamic acid, Cyclokapron” NCT02188576 ↗ |
| Known as | TRANEXEL | “group 1 (TRANEXEL 250 mg/5 mL) patients administered 250 mg tnx acid during the whole bimaxillary orthognathic surgery” NCT06301204 ↗ |
| Known as | Transamin | “1.5 g of tranexamic acid (six ampoules of Transamin®, Zydus Nikkho) diluted in 50 ml of saline solution (0.9 %)” NCT04696224 ↗3“Tranexamic acid (Transamin), Cyklokapron, Exacyl, Cyklo-f) is a synthetic lysine derivative” PMID 12825966 ↗ 2003 “500 mg oral tranexamic acid (Transamin®), taken once daily at bedtime for 12 weeks.” NCT07034560 ↗ “tranexamic acid (Transamin; TEVA Pharma, Istanbul, Turkey)2” NCT05467462 ↗ |
| Known as | Transamin Cap | “Two 250mg capsules of oral TXA(Transamin Cap) is given three times a day, 30 minutes after each meal, from postoperative day 1 to day 5.” NCT03109652 ↗ |
| Known as | Transamine | “10 mg/kg tranexamic acid (Transamine 10% IV/IM Injectable Solution) will be placed into 100 cc physiological saline through the appropriate vascular access and injected within...” NCT06434636 ↗ |
| Known as | Tranxemic acid | “Tranxemic acid (1 g loading dose followed by 3 g maintenance dose over 24- 48 hours) and intravenous injection (10 mg daily of vitamin K for 24-48 h)” NCT06881628 ↗ |
| Known as | TRAXA | “The administration of the tranexamic acid (TRAXA), an antifibrinolytic, blocks primary fibrinolysis” NCT03795649 ↗ |
| Known as | TXA | “The HiFIT study is a multicentre, 2×2 factorial, randomised, double-blinded, controlled trial evaluating the effect of iron isomaltoside (IIM) (20 mg/kg) vs placebo and of TXA...” PMID 33455926 ↗ Jan 2021255“The objective of the proposed clinical trial is to test if perioperative treatment with tranexamic acid (TXA) reduces the early relapses and postoperative complications for...” NCT05899465 ↗ “Tranexamic acid is a promising option for minimizing blood loss in high-risk bariatric surgery patients, particularly in those with obesity, diabetes, and other comorbidities....” NCT07192640 ↗ “This randomized double blinded trial seeks to determine whether tranexamic acid (TXA) is an efficacious treatment for contraceptive induced menstrual changes (CIMC) including...” NCT06000423 ↗ “The study is a prospective, randomized, double blinded, placebo controlled trial that aims to investigate the hypothesis that early administration of tranexamic acid (TXA)...” NCT05518279 ↗ “This study will determine whether treatment with Tranexamic Acid (TXA), an FDA approved medication that reduces bleeding right after ACL injury and reconstructive surgery...” NCT03552705 ↗ “Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality...” NCT06208267 ↗ “This trial will investigate whether Tranexamic Acid (TXA) can increase the rate of CSDH resolution following conservative management, lower the number of required surgical...” NCT02568124 ↗ “INTRODUCTION: We hypothesised that a single preoperative intravenous dose of tranexamic acid (TXA) is effective in patients who undergo total hip arthroplasty (THA) and are at...” PMID 31814452 ↗ Dec 2019 “In response to the World Health Organization call for research on alternative routes for tranexamic acid (TXA) administration in women with postpartum haemorrhage, we examined...” PMID 34998508 ↗ Jan 2022 “Oral tranexamic acid (TXA) is administered at a dose of 1.95 grams per day, divided into three 650 mg capsules taken once daily, starting on postoperative day (POD) 1 through...” NCT07115056 ↗ “Whole Blood Clot Stability and Thrombin Generating Capacity Following Treatment With Bypassing Agents (BPA) With and Without and Tranexamic Acid (TXA) in Haemophilia A Patients...” NCT01800435 ↗ “In Tranexamic group (n=111), patients will be given 1 gm (10 ml) TXA (Kapron, Amoun, Egypt) diluted in 20 ml of Glucose 5% (administered as intravenous infusion over 5 minutes,...” NCT06060327 ↗ “The aim of this study is to investigate whether ultra-early and short-term administration of the antifibrinolytic agent tranexamic acid (TXA), as add-on to standard SAH...” PMID 23680226 ↗ May 2013 “Tranexamic acid (TXA) has been used successfully to stop bleeding after dental procedures, removal of tonsils, prostate surgery, heavy menstrual bleeding, and eye injuries, as...” NCT02644473 ↗ “Although recent studies have assessed tranexamic acid (TXA) pharmacokinetics in different subgroups, the effective concentration of TXA required to completely inhibit...” PMID 26258658 ↗ Dec 2015 “Tranexamic acid (TXA) has been routinely delivered in multisegmental spinal decompression and bone graft fusion surgeries with satisfactory outcomes in minimizing gross blood...” PMID 30755256 ↗ Feb 2019 “Tranexamic acid (TXA) as an antifibrinolytic medication is used to treat or prevent excessive bleeding in significant trauma, surgery, tooth removal, or nasal bleeding,...” NCT04188184 ↗ “Patients in the experimental group will receive a loading dose of tranexamic acid (TXA) at a concentration of 1g/10ml over a period of 10 minutes, administered immediately...” NCT05794321 ↗ “The objective of this study is to evaluate the effect of Tranexamic Acid (TXA) on blood loss and need for perioperative blood transfusion following intertrochanteric and...” NCT02580227 ↗ “tranexamic acid (TXA). In five small retrospective series, this antifibrinolytic drug showed a beneficial effect on the spontaneous resolution of the haematoma, and with that,...” PMID 35042560 ↗ Jan 2022 “One gram of intravenous tranexamic acid (TXA) will be administrated before tourniquet inflation and before closure of the incision, as 1 g has been shown to be a safe amount...” NCT03606109 ↗ “Tranexamic acid (TXA) is a synthetic lysine derivative that blocks the lysine binding site on plasminogen, thus inactivating its conversion to plasmin and hence attenuating its...” NCT06777966 ↗ “The goal of this prospective pragmatic randomized clinical trial is to determine if preoperative administration of tranexamic acid (TXA) reduces bleeding during and after major...” NCT06657924 ↗ “Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that exerts its anti-fibrin lytic effect through the reversible blockade of lysine binding sites on...” NCT02350179 ↗ “OBJECTIVES: To evaluate whether preoperative intravenous tranexamic acid (TXA) reduces postoperative blood transfusion rates in geriatric patients undergoing operative...” PMID 41837612 ↗ Jul 2026 “The systemic use of tranexamic acid (TXA) has been shown to be effective in many types of surgery, reducing the incidence of post-operative bleeding and thereby reducing the...” NCT06038981 ↗ “The objective of this study is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely injured children with hemorrhagic brain...” NCT04387305 ↗ “Literature review suggests that early administration ofTranexamic acid (TXA) reduces mortality due to bleeding in trauma patients (15) and effective in controlling bleeding in...” NCT04788121 ↗ “Purpose: The study aimed to determine whether intravenous administration of tanexamic acid (TXA) before shoulder arthroscopic rotator cuff repair surgery can improve...” NCT04025736 ↗ “This study's objective was to compare the efficacy of both low-power/low-density fractional carbon dioxide (CO2 ) laser and tranexamic acid (TXA) microinjection on post-acne...” PMID 34414642 ↗ Sep 2021 “Tranexamic acid (TXA)® is a lysine analog that prevents the conversion of plasminogen to plasmin and inhibits plasmin's binding to fibrin, stabilizing the fibrin matrix and...” NCT07481682 ↗ “The patients were randomized into 2 groups: the TXA group (received the index procedure with 100-mL IA injection of TXA [30 mg/mL]) and a control group (did not receive IA...” PMID 32743011 ↗ Jul 2020 “It is hypothesized that a strategy using prophylactic oral Tranexamic Acid (TXA) with therapeutic platelet transfusions is safe and effective compared to prophylactic platelet...” NCT02650791 ↗ “Tranexamic acid (TXA) is a well-known antifibrinolytic agent that inhibits fibrin degradation by binding to tissue plasminogen, thereby preventing blood clot lysis and reducing...” NCT07540026 ↗ “Tranexamic acid (TXA), an antifibrinolytic, has been shown to reduce the probability of receiving a blood transfusion by one-third for patients undergoing cardiac or...” PMID 35210348 ↗ Feb 2022 “Tranexamic acid (TXA) is a well-known antifibrinolytic agent that inhibits fibrin degradation by binding to tissue plasminogen, thereby preventing blood clot lysis and reducing...” NCT06421389 ↗ “Tranexamic acid (TXA) is a well-known antifibrinolytic agent that inhibits fibrin degradation by binding to tissue plasminogen, thereby preventing blood clot lysis and reducing...” NCT06107504 ↗ “Oral tranexamic acid (TXA), if effective in reducing blood loss after delivery for women experiencing primary PPH, could be administered where parenteral administration is not feasible.” PMID 32143721 ↗ Mar 2020 “Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that works by reversibly blocking plasminogen and thereby promoting hemostasis through the prevention of fibrin degradation.” NCT04811313 ↗ “Tranexamic acid (TXA) is a fibrinolytic inhibitor which prevents prolonged bleeding by interfering with fibrin clot breakdown by competitively binding to lysine receptors on plasminogen” NCT06345833 ↗ “There is growing evidence that hidden blood loss occurring in the postoperative period is substantial and can potentially be attenuated with the administration of Tranexamic Acid (TXA).” NCT07672158 ↗ “BACKGROUND: Oral as compared to intravenous tranexamic acid (TXA) is an attractive option, in terms of cost and safety, to reduce blood loss and transfusion in total hip arthroplasty.” PMID 38214552 ↗ Jan 2024 “In Tranexamic acid (TXA) group, single intravenous dose of Tranexamic Acid (15mg/kg) diluted in 50 ml of normal saline is administered 30 minutes prior to the induction of anesthesia.” NCT07625709 ↗ “Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from major trauma, postpartum bleeding, surgery, tooth removal, nosebleeds, and heavy menstruation.” NCT04653623 ↗ “The purpose of the proposed study is to evaluate the effects of administering intravenous tranexamic acid (TXA) to patients undergoing anterior cruciate ligament (ACL) reconstruction” NCT03631355 ↗ “Group 1 : Patients in this group will receive an injection of topical tranexamic acid (TXA) into the surgical site(50mg/ml) 10 ml after wound exposure and after wound decompression.” NCT06427850 ↗ “The hemostatic properties of tranexamic acid (TXA) are well described, but the immunological effects of TXA administration after traumatic injury have not been thoroughly examined.” PMID 33013880 ↗ Sep 2020 “This intervention involves topical application of tranexamic acid (TXA) directly to the uterine incision during cesarean delivery, rather than the conventional intravenous route.” NCT07362992 ↗ “Tranexamic acid (TXA) is relatively inexpensive anti-fibrinolytic agent that has been proven effective for decreasing intraoperative blood loss in various surgical specialties.” NCT03553186 ↗ “Epsilon-aminocaproic acid (EACA) and tranexamic acid (TXA) are synthetic amino acid derivatives that interfere with fibrinolysis, promoting hemostasis by pharmacological means.” PMID 28976426 ↗ Oct 2017 “Objective: To review the mechanism of action, pharmacology, dosing, and complications of tranexamic acid (TXA) and consolidate current evidence for TXA in gynecologic surgery.” PMID 31865770 ↗ Jan 2020 “Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to be effective in reducing blood loss and the need for transfusions after several orthopaedic surgeries.” NCT05321199 ↗ “INTRODUCTION: Few studies have focused on therapeutic as well as side effects of tranexamic acid (TXA) as a topical drug compared to other topical drugs in treating melasma.” PMID 28748406 ↗ Jul 2017 “Tranexamic acid (TXA) is a synthetic analog of serin than reversibly inhibits fibrinolysis by blocking lysine union sites in the plasmin and plasminogen activator molecules.” NCT02653261 ↗ “Tranexamic acid (TXA) is a drug that is being used more frequently at the Hospital for Special Surgery to lessen the amount of blood loss after total knee replacement (TKR).” NCT02540226 ↗ “Tranexamic acid (TXA) is a synthetic antifibrinolytic drug that competitively inhibits the lysine binding sites of plasminogen, plasmin, and tissue plasminogen activator.” NCT01094977 ↗ “Group A 30 patients treated with Intradermal Tranexamic acid injection (4mg/ml) for preparation an insulin syringe was used with a volume of 1ml containing 0.04 ml of TXA” NCT05884151 ↗ “Tranexamic acid (TXA) is a potent antifibrinolytic with documented efficacy in reducing blood loss and allogeneic red blood cell transfusion in several clinical settings.” PMID 35977357 ↗ Aug 2022 “Tranexamic acid (TXA), administered soon after hospital arrival in certain trauma systems, is an effective therapy in preventing or managing acute traumatic coagulopathy.” PMID 33722875 ↗ Mar 2021 “Tranexamic acid (TXA) is an inexpensive and widely available medication that reduces blood loss and red blood cell (RBC) transfusion in cardiac and orthopaedic surgeries.” PMID 38830735 ↗ Jun 2024 “Hence, one of ICH's main acute therapeutic strategies is to reduce hematoma expansion (HE) with hemostatic agents like tranexamic acid (TXA) or recombinant factor VIIa.” NCT07365150 ↗ “Fortunately, there is an inexpensive, commonly used drug, tranexamic acid (TXA) which suppresses this conversion and could be re-purposed for the treatment of COVID19.” NCT04338126 ↗ “Tranexamic acid (TXA) is an antifibrinolytic agent that decreases bleeding in various settings, but has not been well studied in patients undergoing liver resection.” PMID 27765582 ↗ Oct 2016 “Objective to assess the value of preoperative tranexamic acid (TXA) in reduction of intraoperative and postoperative blood loss in high-risk cesarean delivery (CD).” PMID 35287618 ↗ Mar 2022 “Topical Tranexamic Acid (TXA) is an antifibrinolytic agent which stabilises clot formation and is infiltrated into local tissues perioperatively prior to closure.” NCT07455591 ↗ “Tranexamic acid (TXA) is a synthetic inhibitor of plasminogen lysine receptor that has used to reduce intra-operative bleeding in a number of clinical scenarios.” NCT04951128 ↗ “This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery.” NCT07131592 ↗ “PURPOSE: To further clarify the role of tranexamic acid (TXA) in arthroscopic rotator cuff repair (ARCR), especially visual field clarity and operation time.” PMID 37423470 ↗ Jul 2023 “To determine whether intraoperative tranexamic acid (TXA) administration reduced intraoperative blood loss in patients undergoing large meningioma resection.” PMID 42115323 ↗ May 2026 “Use of tranexamic acid (TXA) for the prevention of postpartum haemorrhage (PPH) after cesarean section in high-risk patients ( a randomized control trial ).” NCT04707950 ↗ “One gram of intravenous tranexamic acid (TXA) in normal saline (50cc) given over 15 minutes starting just prior to skin incision, and repeated 4 hours later” NCT03970213 ↗ “Drug: Tranexamic Acid 20 mL TXA (100 mg/mL injection solution, total 2g TXA) applied topically to the mastectomy cavity for 5 minutes before wound closure” NCT03738527 ↗ “Tranexamic acid (TXA) has proven efficacy in decreasing blood loss in general trauma patients as well as patients undergoing elective orthopaedic surgery.” PMID 27329438 ↗ Jun 2016 “Tranexamic acid (TXA) is a synthetic antifibrinolytic agent successfully used intravenously (IV) to reduce blood loss after total knee arthroplasty (TKA).” PMID 27113948 ↗ Mar 2016 “Tranexamic Acid (TXA) is a safe and effective antifibrinolytic drug used systemically to control bleeding and topically to treat melasma and rosacea.” NCT06644079 ↗ “Tranexamic acid (TXA) is an antifibrinolytic agent that acts to decrease bleeding by stabilizing the fibrin matrix involved in the clotting cascade.” NCT06057675 ↗ “Tranexamic acid (TXA) will be administered perioperatively according to institutional protocol to reduce intraoperative and postoperative bleeding.” NCT07501884 ↗ “Topical tranexamic acid (TXA) has been demonstrated as an effective intervention that reduced acute postoperative pain in total knee arthroplasty.” PMID 40398932 ↗ May 2025 “Trials of tranexamic acid (TXA) in acute intracerebral hemorrhage (ICH) have focused on the imaging outcomes of intraparenchymal hematoma growth.” PMID 35300248 ↗ Feb 2022 “Tranexamic acid (TXA) is an antifibrinolytic drug that has been used off-label for the treatment of melasma, as an oral or intradermal injection.” NCT06522984 ↗ “Tranexamic acid (TXA) is an antifibrinolytic agent widely used in surgery to decrease bleeding and reduce the need for blood product transfusion.” PMID 36952300 ↗ Jun 2023 “Microneedling with topical tranexamic acid (TXA) was proved to be safe, effective and comparatively painless without any detectable side effects.” NCT05909072 ↗ “Effect of Tranexamic Acid (TXA) Administered Prior to Shoulder Arthroscopy on Postoperative Pain Medication Usage: A Randomized Controlled Trial” NCT06920264 ↗ “Tranexamic acid (TXA), an antifibrinolytic agent, and tocilizumab (TCZ), an anti-inflammatory agent, represent promising therapeutic candidates.” PMID 42423601 ↗ Jul 2026 “FDA-approved usage for intravenous tranexamic acid (TXA) is for heavy menstrual bleeding and short-term prevention in patients with hemophilia.” NCT04814433 ↗ “Intravenous tranexamic acid (IV TXA) is one of the most effective agents in use for reducing blood loss following total knee arthroplasty (TKA)” NCT02829346 ↗ “Tranexamic acid (TXA) is a drug that has proved useful in reducing bleeding associated with other surgeries and CRT results have been positive” NCT01199627 ↗ “Patients eligible for inclusion will be randomized to receive treatment with Tranexamic acid (TXA) as an adjunct to surgery or surgery alone.” NCT07245264 ↗ “Tranexamic acid (TXA) is a drug that interferes with fibrinolysis, in use for more than 50 years in surgery, particularly in cardiac surgery.” NCT04696224 ↗ “Tranexamic acid (TXA) is an antifibrinolytic medication (reduces the destruction of blood clots, thus promoting the ability to stop bleeding)” NCT02043132 ↗ “Tranexamic acid (TXA) a hemostatic drug that is widely available and safe can be a cost-effective treatment for ICH, if proven efficacious.” PMID 39633570 ↗ Jan 2025 “intravenous application of tranexamic acid1 g TXA before incision, followed by two boluses (1g TXA) three hours later and six hours later.” NCT03623789 ↗ “Tranexamic Acid (TXA) is administered intravenously to prevent bleeding associated with cardiac surgery and by pass in adult and children.” NCT01141127 ↗ “Tranexamic acid (TXA), is commonly administered prophylactically to reduce blood loss in patients undergoing total hip arthroplasty (THA).” PMID 40735345 ↗ Jul 2025 “Tranexamic acid (TXA) and the hemostatic agent Floseal® have already been used to minimize bleeding during total knee arthroplasty (TKA).” PMID 31778430 ↗ Nov 2019 “Tranexamic acid (TXA) has emerged in the literature as a promising agent that reduces perioperative blood loss and need for transfusion.” NCT04947514 ↗ “Tranexamic acid (TXA) is used as a synthetic anti-fibrinolytic agent for total knee arthroplasty (TKA) to reduce postoperative bleeding.” PMID 35109837 ↗ Feb 2022 “Many antifibrinolytic agents, including tranexamic acid (TXA), have been used in orthopedic surgeries to reduce postoperative bleeding.” NCT03580018 ↗ “The aim is to assess the impact of tranexamic acid (TXA) for preventing postpartum hemorrhage (PPH) following a cesarean section (CS).” NCT03431805 ↗ “Tranexamic acid (TXA) is a lysine synthetic derivate that inhibits fibrinolysis by blocking the 5 lysine-binding sites to plasminogen.” NCT04430777 ↗ “Tranexamic acid (TXA) is an antifibrinolytic used worldwide to treat uterine haemorrhage and to reduce blood loss in general surgery.” PMID 28413832 ↗ Dec 2016 “Tranexamic acid (TXA), the study agent, or matching placebo will be prescribed as a 650mg tablet to be taken once daily for 21 weeks.” NCT06718751 ↗ “No prior study in orthognathic surgery has isolated the effects of tranexamic acid (TXA) from deliberate hypotensive anesthesia (HA).” PMID 40975121 ↗ Sep 2025 “The study intervention involves administering nebulized tranexamic acid (TXA) to pediatric patients with traumatic hemorrhage (PTH).” NCT06580509 ↗ “The purpose of this study is to find an optimal dose of tranexamic acid (TXA) to be given during a hip or knee replacement surgery.” NCT05075200 ↗ “A single preoperative dose of tranexamic acid (TXA) reduces blood loss and red blood cell transfusion in primary hip arthroplasty.” NCT03822793 ↗ “Tranexamic acid (TXA) is a synthetic analog of lysine that inhibits fibrinolysis by preventing plasminogen from binding to fibrin” NCT07157631 ↗ “The tranexamic acid (TXA) group will receive a single bolus IV injection of 15 mg/kg of TXA 20 minutes before surgical incision” NCT04357015 ↗ “extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots” NCT07685743 ↗ “Tranexamic acid (TXA), an antifibrinolytic drug, has been shown to decrease hematoma volume in a small cohort of CSDH patients.” NCT04898712 ↗ “Tranexamic acid (TXA), a synthetic antifibrinolytic agent, has recently gained attention as a promising treatment for melasma.” NCT07495748 ↗ “Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that binds to the lysine binding sites of plasmin and plasminogen.” NCT03112135 ↗ “Tranexamic acid (TXA) is an agent that has been shown to be safe and effective to reduce blood loss in surgical procedures.” NCT04312880 ↗ “Evaluate the efficacy of oral administration of tranexamic acid (TXA) in spine surgeries to achieve blood loss reduction.” NCT05705336 ↗ “This study aimed to evaluate the effect of tranexamic acid (TXA) on blood transfusion requirements in acute burn surgery.” PMID 35339324 ↗ Mar 2022 “Tranexamic acid (TXA) is an antifibrinolytic agent that has been used to reduce bleeding complications in other settings.” PMID 37882229 ↗ Oct 2023 “Tranexamic acid (TXA) is an agent, first patented in 1957, that competitively inhibits plasmin generation and activity.” NCT04724772 ↗ “Topical administration of tranexamic acid (TXA) may be an alternative to intravenous administration to reduce bleeding” PMID 32207575 ↗ Dec 2019 “Tranexamic acid (TXA), an inhibitor of fibrinolysis, was reportedly effective reducing blood loss after standard TKA.” NCT03328832 ↗ “The benefit of tranexamic acid (TXA) in pediatric cardiac surgery on postoperative bleeding has varied among studies.” PMID 21947753 ↗ Sep 2011 “The study group received perioperative intravenous tranexamic acid (TXA) while the control group received a placebo.” PMID 38283394 ↗ Jan 2024 “Patients in the Tranexamic Acid (TXA) group (arm-A) will be administered with 2 doses of intravenous tranexamic acid” NCT04803591 ↗ “Tranexamic acid (TXA) treatment is receiving increased emphasis in obstetric care because TXA inhibits fibrinolysis.” NCT03856164 ↗ “Perioperative tranexamic acid (TXA) use can reduce bleeding and transfusion requirements in several types of surgery” PMID 28203735 ↗ Mar 2017 “The goal of this clinical trial is to learn if tranexamic acid (TXA) helps reduce bleeding during bariatric surgery” NCT07098780 ↗ “Tranexamic acid (TXA) is commonly given to surgical patients to reduce bleeding and the need for blood transfusion.” NCT01402882 ↗ “This trial is to determine the effect of Tranexamic Acid (TXA) on blood loss during endoscopic pituitary surgery.” NCT04863339 ↗ “The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients.” PMID 28143564 ↗ Jan 2017 “By inhibiting the proinflammatory actions of plasmin, tranexamic acid (TXA) may decrease postoperative delirium.” PMID 40276619 ↗ Apr 2025 “Intravenous and topical tranexamic acid (TXA) have been well established in reducing blood loss postoperatively.” NCT03074994 ↗ “In neurosurgical setting, a large sample size trials of tranexamic acid (TXA) has been limited to TBI and SAH.” NCT04386642 ↗ “Tranexamic acid (TXA) is used commonly in obstetrics to prevent or manage intrapartum or postpartum hemorrhage” NCT06820177 ↗ “A controlled trial of the drug tranexamic acid (TXA) in outpatients who were recently diagnosed with COVID-19.” NCT04338074 ↗ “Tranexamic acid (TXA) may help control the bleeding by counterbalancing cirrhosis-related hyperfibrinolysis.” PMID 30099397 ↗ Aug 2018 “Tranexamic acid (TXA) is an antifibrinolytic drug that competitively inhibits the activation of plasminogen.” NCT06149091 ↗ “Tranexamic acid (TXA) is a clot promoting agent utilized during orthopedic procedures to decrease bleeding.” PMID 36222618 ↗ Dec 2022 “Tranexamic acid (TXA), an antifibrinolytic agent, is widely used in orthopedic surgery to reduce bleeding” NCT07610863 ↗ “Tranexamic acid (TXA) has demonstrated efficacy in other surgical fields and in bariatric pilot studies.” PMID 38719323 ↗ May 2024 “tranexamic acid (TXA group) and fibrin glue (FG group) administered topically prior to surgical closure” PMID 36045358 ↗ Aug 2022 “Tranexamic acid (TXA) has been shown to reduce intraoperative blood loss and improve the visual field.” PMID 36608352 ↗ Feb 2023 “The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage” PMID 30376893 ↗ Oct 2018 “Tranexamic acid (TXA), a Food and Drug Administration (FDA) approved synthetic antifibrinolytic agent” NCT06088407 ↗ “Tranexamic acid (TXA) is an anti-fibrinolytic effective in reducing blood loss in orthopedic surgery.” PMID 35751772 ↗ Jun 2022 “prehospital tranexamic acid (TXA) was associated with lower mortality in specific patient subgroups.” PMID 37125811 ↗ May 2023 “Tranexamic acid (TXA) is a synthetic reversible competitive inhibitor to plasminogen lysine receptor” NCT06450392 ↗ “All enrolled patients with acute trauma were given 1 g tranexamic acid (TXA) within 3 h after trauma” NCT06736860 ↗ “tranexamic acid (TXA) was applied topically to the mastectomy wound at the time of surgical closure” NCT07434453 ↗ “Tranexamic acid (TXA) reduces bleeding by inhibiting the enzymatic breakdown of fibrin blood clots.” PMID 37664793 ↗ Aug 2023 “there is an inexpensive, commonly used drug, tranexamic acid, TXA, which suppresses this conversion” NCT04550338 ↗ “Tranexamic acid (TXA) is widely used across surgical specialties to reduce perioperative bleeding.” PMID 33475421 ↗ Jan 2021 “There has been interest lately in oral medications like tranexamic acid (TXA ) to improve melasma” NCT07448415 ↗ “Tranexamic acid (TXA) reduces blood loss and transfusion in paediatric craniosynostosis surgery.” PMID 32620262 ↗ Jun 2020 “The use of Tranexamic Acid (TXA) intravenously, to Reduce Blood Loss in proximal femur surgery.” NCT02164565 ↗ “1.0 g single dose of tranexamic acid (TXA), intravenously administered (over 10 mins) on Day 4.” NCT02561923 ↗ “Tranexamic acid, also known as TXA, is a cheap drug that reduces bleeding in other conditions.” PMID 34663491 ↗ Oct 2021 “Tranexamic acid (TXA) will be injected to distinction media during hysteroscopy in myomectomy” NCT03122782 ↗ “Tranexamic acid (TXA) is an antifibrinolytic that is widely used to reduce surgical bleeding.” PMID 37857168 ↗ Oct 2023 “Prophylactic tranexamic acid (TXA) reduces blood loss during cardiac and orthopedic surgery” PMID 39356537 ↗ Dec 2024 “Tranexamic acid (TXA) is a synthetic, competitive lysine receptor inhibitor on plasminogen.” NCT06428682 ↗ “Tranexamic acid (TXA) is a novel agent used in the treatment of post burn hyperpigmentation” NCT07263841 ↗ “Tranexamic acid (TXA) is an antifibrinolytic drug potentially limiting hematoma expansion.” PMID 37466000 ↗ Jul 2023 “intravenous (IV), intramuscular (IM) and oral tranexamic acid (TXA) use in pregnant women.” PMID 37019443 ↗ Apr 2023 “Tranexamic acid (TXA) has been used widely for the reduction of post operative blood loss” NCT02947529 ↗ “The application of additional tranexamic acid (TXA) to the ulcer may enhance hemostasis.” PMID 37356632 ↗ Jun 2023 “Data on use of other agents such as tranexamic acid (TXA) for this purpose are limited.” PMID 36273651 ↗ Oct 2022 “tranexamic acid (TXA) as a prophylactic agent in reducing postpartum haemorrhage (PPH)” NCT07474077 ↗ “Intravenous tranexamic acid (TXA) reduces bleeding deaths after injury and childbirth.” PMID 33010927 ↗ Sep 2020 “Topical tranexamic acid (TXA) and ascorbic acid are both effective in treating melasma” NCT07522788 ↗ “50 patients were given 1 gram of Tranexamic acid (TXA) intravenously pre-operatively.” NCT04986813 ↗ “Tranexamic acid(TXA), an antifibrinolytic agent, is widely used to reduce bleeding” PMID 40358732 ↗ May 2025 “tranexamic acid (TXA), given via intra-articular injection at the time of surgery” NCT03458468 ↗ “tranexamic acid (TXA) administration in cases of trauma-induced hemorrhagic shock” PMID 28611888 ↗ Apr 2017 “to adjust the duration of antifibrinolytic treatment with tranexamic acid (TXA).” PMID 23195143 ↗ Nov 2012 “Tranexamic acid (TXA), an antifibrinolytic agent, reduces perioperative bleeding” NCT07288697 ↗ “The Effect of Tranexamic Acid (TXA) on Visualization During Shoulder Arthroscopy” NCT04610164 ↗ “Intravenous (IV) tranexamic acid (TxA) is a commonly used antifibrinolytic drug” PMID 30908754 ↗ Mar 2019 “Tranexamic acid (TXA) has been widely applied to reduce perioperative bleeding.” PMID 36199695 ↗ Sep 2022 “Tranexamic acid (TXA) reduces bleeding in patients undergoing elective surgery.” PMID 23477634 ↗ Mar 2013 “red blood cells transfusion, tranexamic acid (TXA) and fibrinogen concentrate” NCT04111822 ↗ “Effectiveness of Tranexamic acid(TXA) is unknown in foot and ankle surgeries.” NCT03653429 ↗ “Empirical Tranexamic acid (TXA) administration after the anesthesia induction” NCT05957822 ↗ “red blood cells (RBC), Tranexamic acid (TXA) and Fibrinogen Concentrate (FC)” NCT04149171 ↗ “To compare intravenous Tranexamic Acid (TXA) versus normal saline placebo” NCT02569658 ↗ “intravenous tranexamic acid (TXA), a drug with anti-fibrinolytic activity” NCT02806024 ↗ “tranexamic acid (TXA; a medication that prevents clots from dissolving)” NCT06599762 ↗ “The tranexamic acid (TXA) can reduce surgical perioperative blood loss.” PMID 27856355 ↗ Nov 2016 “the other side will be treated with intradermal tranexamic acid (TXA).” NCT03885895 ↗ “Tranexamic acid (TXA) is a compound that comes from amino acid lysine.” NCT07280234 ↗ “Tranexamic acid (TXA) prevents the breakdown of clots and fibrinolysis” NCT06707051 ↗ “tranexamic acid (TXA) nebulization to control bleeding in hemoptysis.” PMID 41221568 ↗ Oct 2025 “Tranexamic acid (TxA) is a drug that was approved by the FDA in 1986.” NCT05554211 ↗ “applying the drug tranexamic acid (TXA) onto a surgical wound surface” NCT06270407 ↗ “L’acide tranexamique (TXA) a permis de réduire les pertes sanguines” PMID 34388107 ↗ Aug 2021 “The G1 group received 1 g of intra-articular tranexamic acid (TXA).” NCT04085575 ↗ “Tranexamic Acid(TXA) is a traditional method to reduce blood loss” NCT03934047 ↗ “Tranexamic Acid (TXA) is given to stop or reduce heavy bleeding.” NCT03825939 ↗ “Tranexamic acid (TXA) is a medicine used to treat heavy periods.” NCT06519422 ↗ “single bolus IV injection of 15 mg/kg of tranexamic acid (TXA)” NCT04357002 ↗ “Tranexamic acid (TXA) effectively attenuates hyperfibrinolysis” PMID 39334224 ↗ Sep 2024 “Tranexamic acid (TXA) is a widely used antifibrinolytic agent” NCT06128330 ↗ “Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent” NCT06638749 ↗ “Local application of TXA impregnated in a gelatin sponge” NCT05439694 ↗ “Tranexamic acid (TXA) is an antifibrinolytic medication” NCT02908516 ↗ “Tranexamic acid (TXA), an inhibitor of fibrinolysis” NCT05099276 ↗ “two doses of intravenous (IV) tranexamic acid (TXA)” NCT05874583 ↗ “Tranexamic acid (TXA) reduces head injury deaths.” NCT04521881 ↗ “Tranexamic acid (TXA), an antifibrinolytic agent” NCT02302456 ↗ “Tranexamic acid (TXA) is synthetic lysine analog” NCT04443920 ↗ “Tranexamic acid (TXA), an antifibrinolytic agent” NCT07460518 ↗ “intravenously administered tranexamic acid (TXA)” NCT05397652 ↗ “topical tranexamic acid (TXA) (one finger unit)” NCT04599205 ↗ “Irrigation that contains tranexamic acid (TXA)” NCT05441592 ↗ “oral tranexamic acid (TXA) or placebo regimen” NCT06479161 ↗ “ARM2: Intravenous Tranexamic Acid (TXA) Group” NCT07442643 ↗ “tranexamic acid (TXA), an anti-fibrinolytic” NCT04918589 ↗ “intravenous tranexamic acid (TXA) infusion” NCT02747615 ↗ “1gm of Tranexamic acid (TXA) intravenously” NCT05759156 ↗ “intravenous tranexamic acid (TXA) infusion” NCT06760078 ↗ “Tranexamic Acid (TXA) 2 gm intraoperative” NCT04766996 ↗ “Conventional Oral TXA (Tranexamic Acid)” NCT02926651 ↗ “Tranexamic acid (TXA) is a medication” NCT02753816 ↗ “Tranexamic acid (TXA) injection” NCT04650698 ↗ “Tranexamic Acid (TXA) treatment” NCT07089251 ↗ “Tranexamic Acid Injection (TXA)” NCT04560010 ↗ “1 gram Tranexamic Acid (TXA)” NCT01990768 ↗ “Tranexamic Acid (TXA) Group” NCT07423156 ↗ “Drug: Tranexamic Acid (TXA)” NCT07212452 ↗ “Drug: Tranexamic Acid (TXA)” NCT06330935 ↗ “Tranexamic acid (TXA).” NCT03136445 ↗ “Tranexamic Acid (TXA)” NCT07169383 ↗ “Tranexamic Acid (TXA)” NCT06879353 ↗ “Tranexamic acid (TXA)” NCT07494032 ↗ “Tranexamic acid (TXA)” NCT05713630 ↗ “Tranexamic acid (TXA)” NCT02860221 ↗ “Tranexamic Acid (TXA)” NCT06356948 ↗ “Tranexamic acid (TXA)” NCT02864095 ↗ “Tranexamic Acid (TXA)” NCT07401394 ↗ “Tranexamic Acid (TXA)” NCT04347122 ↗ “Tranexamic Acid (TXA)” NCT02329756 ↗ “Tranexamic acid (TXA)” NCT03679481 ↗ “Tranexamic Acid (TXA)” NCT06725732 ↗ “Tranexamic acid (TXA)” NCT05802238 ↗ “Tranexamic Acid (TXA)” NCT07116395 ↗ “Tranexamic Acid (TXA)” NCT07034560 ↗ “Tranexamic Acid (TXA)” NCT07392034 ↗ “Tranexamic acid (TXA)” NCT01937559 ↗ “Tranexamic Acid (TXA)” NCT03182751 ↗ “tranexamic acid (TXA)” NCT03806556 ↗ “Tranexamic Acid (TXA)” NCT06070350 ↗ “Tranexamic Acid (TXA)” NCT04907812 ↗ “Tranexamic Acid (TXA)” NCT07002749 ↗ “tranexamic acid(TXA)” NCT05427513 ↗ “tranexamic acid(TXA)” NCT03109652 ↗ “TXA” NCT05774717 ↗ |
| Action | Inhibit | “tranexamic acid is thought to exert its effect through inhibition of fibrinolysis” PMID 21439633 ↗ Mar 2011 |
| Modality | Small molecule | “Tranexamic acid is a synthetic amino acid with antifibrinolytic action” NCT00444470 ↗ |
| Route | Oral | “an oral tranexamic acid (TA) formulation” PMID 21867401 ↗ Aug 2011 |