Efficacy of Tranexamic Acid in Reducing Myomectomy Associated Blood Loss in Federal Teaching Hospital Abakaliki.

NCT04560465 ↗

Phase 2 Completed 59 enrolled Alex Ekwueme Federal University Teaching Hospital

RandomizedParallel-groupTriple-blindTreatment

Summary

to determine safety and efficacy of Tranexamic Acid in reducing blood loss during Myomectomy in our institution.

Timeline

Start: 2018-06-01
Primary completion: 2019-05-31
Completion: 2019-06-01

Outcome

Met primary endpoint

paper Perioperative tranexamic acid infusion therefore reduced mean intraoperative blood loss by 300 ml, and this was statistically significant (SMD = -0.212, 95% CI: -403.932 to -196.067, P < 0.0001). PMID 38283394 ↗

Publications

Olaleye AA, Adebayo JA, Eze JN, Ajah LO, Anikwe CC, Egede JO, Ebere CI. Efficacy of Tranexamic Acid in Reducing Myomectomy-Associated Blood Loss among Patients with Uterine Myomas at Federal Teaching Hospital Abakaliki: A Randomized Control Trial. Int J Reprod Med. 2024 Jan 18;2024:2794052. doi: 10.1155/2024/2794052. eCollection 2024.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tranexamic Acid	Small molecule	1000 mg	Intravenous

Indications

No indication recorded.