drugset / Trial / NCT07845370

Topical Tranexamic Acid Spray Versus No Spray on Postoperative Outcomes Following Mesh Repair of Umbilical Hernia

NCT07845370 ↗

Not yet recruiting 252 enrolled Dr Mudassar Saeed Pansota
RandomizedParallel-groupOpen-labelTreatment

Summary

Umbilical hernia is a type of ventral hernia that occurs commonly in adulthood, and mesh reinforcement is well established since there is a reduced recurrence rate when compared to suture repair. However, the repair of meshes could prove to be complex due to seroma, hematoma, wound infection, pain, and other surgical-site events.3 Seroma formation is considered clinically significant due to its ability to be painful, recurrent outpatient care, aspiration, infection, and slow wound healing.

Timeline

Start
2026-09-15
Primary completion
2026-12-14
Completion
2026-12-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Tranexamic Acid Small molecule 1 g Topical