drugset / Trial / NCT04390217
LB1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a Phase 2, proof of concept, randomized, placebo-controlled, multicenter study to evaluate the ability of LB1148 to attenuate pulmonary dysfunction associated with COVID-19 pneumonia. The primary objective of this study is to determine if enteral administration of LB1148 will effect disease progression in hospitalized patients with moderate to severe COVID-19 via measurement of the proportion of subjects alive and free of respiratory failure at Day 28.
Timeline
- Start
- 2021-10-31
- Primary completion
- 2021-12-31
- Completion
- 2022-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tranexamic Acid | Small molecule | 350 ml | Oral |