drugset / Trial / NCT02312440
Comparison of Topical and Intravenous Tranexamic Acid in Total Hip Arthroplasty
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Recently, there has been interest in applying tranexamic acid topically before the closure of surgical wounds in total hip replacement. It has the advantages of ease of application, maximum concentration at the site of bleeding, minimising its systematic absorption and, potentially , decline the risks for systematic side-effects 。
Timeline
- Start
- 2014-10
- Primary completion
- 2015-08
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tranexamic Acid | Small molecule | 10 mg/kg | Intravenous |
| Subject | Tranexamic Acid | Small molecule | 3 g | Intravenous |
Indications
No indication recorded.