drugset
drugset / Trial / NCT02393300

Comparison of Topical Versus Intravenous Tranexamic Acid in TKA

NCT02393300 ↗

Phase 3 Completed 174 enrolled Shanghai Jiao Tong University School of Medicine
RandomizedParallel-groupTriple-blindTreatment

Summary

Previous studies in both the cardiovascular and orthopedic study have shown tranexamic acid (TXA) reduces blood loss and post-operative blood transfusion rate largely without major complications . In addition, many meta-analyses have confirmed these results . However, there is little information about comparison among the different routes of TXA administration in TKA. Therefore, this study has been designed to determine which administration route of TXA is more effective and safety.

Timeline

Start
2014-07
Primary completion
2015-05
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Tranexamic Acid Small molecule 10 mg/kg Intravenous
Subject Tranexamic Acid Small molecule 3 g Intravenous

Indications

No indication recorded.