drugset / Trial / NCT06337838
Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
Phase 3
Recruiting
100 enrolled
Hamilton Health Sciences Corporation
Population Health Research Institute · collab
RandomizedFactorialQuadruple-blindTreatment
Summary
The BRACKETS pilot study is a multicentre, prospective, randomized controlled trial of prophylactic preoperative tranexamic acid (TXA) versus placebo and, using a partial factorial design, of prophylactic preoperative desmopressin versus placebo.
Timeline
- Start
- 2025-06-09
- Primary completion
- 2027-02
- Completion
- 2027-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Desmopressin | Peptide | 20 ug | Intravenous |
| Subject | Tranexamic Acid | Small molecule | 500 mg | Intravenous |
| Subject | Tranexamic Acid | Small molecule | 1000 mg | Intravenous |