drugset / Trial / NCT07825350

HTO and Tranexamic Acid Study

NCT07825350 ↗

Phase 3 Not yet recruiting 200 enrolled Western University, Canada
RandomizedParallel-groupQuadruple-blindPrevention

Summary

The purpose of the study is to assess the effect of Tranexamic acid (TXa), a commonly used medication to prevent bleeding, in reducing blood loss during High Tibial Osteotomy (HTO). HTO is a common procedure aimed at realigning patients that are bow-legged, in an attempt to reduce pain associated with osteoarthritis of the knee, and to prevent its progression. A secondary aim is to assess the effect of TXa in preventing side-effects of surgery related to the healing of surgical wound.

Timeline

Start
2027-01-01
Primary completion
2030-01-01
Completion
2032-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tranexamic Acid Small molecule 15 mg/kg Intravenous

Indications