drugset / Trial / NCT07825350
HTO and Tranexamic Acid Study
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The purpose of the study is to assess the effect of Tranexamic acid (TXa), a commonly used medication to prevent bleeding, in reducing blood loss during High Tibial Osteotomy (HTO). HTO is a common procedure aimed at realigning patients that are bow-legged, in an attempt to reduce pain associated with osteoarthritis of the knee, and to prevent its progression. A secondary aim is to assess the effect of TXa in preventing side-effects of surgery related to the healing of surgical wound.
Timeline
- Start
- 2027-01-01
- Primary completion
- 2030-01-01
- Completion
- 2032-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tranexamic Acid | Small molecule | 15 mg/kg | Intravenous |