The Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Caesarean Section

Phase 3 Completed 1226 enrolled University of Zimbabwe Fogarty International Center of the National Institute of Health · collab

RandomizedParallel-groupDouble-blindPrevention

Summary

This study seeks to determine if the using tranexamic acid prophylactically at caesarean section will prevent postpartum haemorrhage which is a major cause of maternal mortality in Zimbabwe and globally.

Timeline

Start: 2021-03-23
Primary completion: 2021-12-14
Completion: 2021-12-14

Publications

Gwanzura C, Gavi S, Mangiza M, Moyo FV, Lohman MC, Nhemachena T, Chipato T. Effect of anesthesia administration method on apgar scores of infants born to women undergoing elective cesarean section. BMC Anesthesiol. 2023 Apr 27;23(1):142. doi: 10.1186/s12871-023-02098-w.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tranexamic Acid	Small molecule	1 g	Intravenous

Indications

No indication recorded.