The Effect of Amlodipine and Lisinopril on Retinal Autoregulation in Type 1 Diabetes

Summary

The purpose of this study is to compare the effect of two antihypertensive drugs on retinal vessel diameter in young type 1 diabetics. The retinal vessel analyzer (RVA) was used to investigate how the drugs affected vessel diameter, when the subjects were exposed to an increase in blood pressure, induced by isometric muscle contraction and when they were stimulated by flickering light.

Timeline

Start

2006-07

Primary completion

2009-02

Completion

2009-02

Drugs

Indications