drugset / Trial / NCT00337532
A Phase II Trial Neoadjuvant Paclitaxel and Cisplatin in Patients With Locally Advanced Head and Neck Cancer
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this clinical research study is to learn if a paclitaxel-cisplatin combination regimen given in the neoadjuvant setting is active in locally advanced head and neck cancer. the safety of this treatment will also be studied.
Timeline
- Start
- 2005-05
- Primary completion
- 2007-06
- Completion
- 2007-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cisplatin | Other / unclassified | 45 mg/m2 | Intravenous |
| Comparator | Cisplatin | Other / unclassified | 60 mg/m2 | Intravenous |
| Comparator | Cisplatin | Other / unclassified | 75 mg/m2 | Intravenous |
| Comparator | Paclitaxel | Small molecule | 105 mg/m2 | — |
| Comparator | Paclitaxel | Small molecule | 140 mg/m2 | — |
| Comparator | Paclitaxel | Small molecule | 175 mg/m2 | — |