drugset / Trial / NCT00346567
Backup With Combivir or Single Dose (SD) Truvada in Order to Avoid Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) Resistance After SD Nevirapine for the Prevention of Mother-to-child Transmission (PMTCT)
RandomizedParallel-groupOpen-labelPrevention
Summary
The aim of the study is to find short course alternatives to single dose (sd)nevirapine for the prevention of mother-to-child HIV-transmission with the same or better degree of transmission protection than sd nevirapine but with less NNRTI resistance development.
Timeline
- Start
- 2006-06
- Primary completion
- 2010-10
- Completion
- 2011-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lamivudine | Other / unclassified | — | — |
| Subject | Tenofovir | Small molecule | — | — |
| Subject | emtricitabine | Other / unclassified | — | — |
| Comparator | Zidovudine | Small molecule | — | — |