drugset / Trial / NCT00351286

Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease

NCT00351286

Phase 2 Unknown 160 enrolled Angiogenix
RandomizedParallel-groupDouble-blindTreatment

Summary

To prove the combination of L-citrulline with simvastatin leads to greater improvement in the symptoms of peripheral arterial disease (PAD) than simvastatin alone by evaluating oral L- citrulline or placebo against simvastatin for improvement in treadmill walking distance in patients, 40-75 years of age, who have PAD with intermittent claudication.

Timeline

Start
2006-03
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject L-citrulline Other / unclassified 1000 mg Oral
Background Simvastatin Small molecule 40 mg