drugset / Trial / NCT00351286
Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease
RandomizedParallel-groupDouble-blindTreatment
Summary
To prove the combination of L-citrulline with simvastatin leads to greater improvement in the symptoms of peripheral arterial disease (PAD) than simvastatin alone by evaluating oral L- citrulline or placebo against simvastatin for improvement in treadmill walking distance in patients, 40-75 years of age, who have PAD with intermittent claudication.
Timeline
- Start
- 2006-03
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | L-citrulline | Other / unclassified | 1000 mg | Oral |
| Background | Simvastatin | Small molecule | 40 mg | — |