drugset / Trial / NCT00357240
Drug Interaction Study With Proton Pump Inhibitor
RandomizedParallel-groupOpen-label
Summary
The purpose of this clinical research study is to assess the effect of omeprazole at 20 mg on the pharmacokinetics of atazanavir administered as atazanavir with ritonavir relative to atazanavir or atazanavir/ritonavir in the absence of omeprazole in healthy subjects.
Timeline
- Start
- 2006-06
- Primary completion
- 2006-08
- Completion
- 2006-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atazanavir | Other / unclassified | 300 mg | Oral |
| Comparator | Atazanavir | Other / unclassified | 400 mg | Oral |
| Subject | Omeprazole | Other / unclassified | 20 mg | Oral |
| Comparator | Ritonavir | Other / unclassified | 100 mg | Oral |