drugset / Trial / NCT00357604
Atazanavir and Ritonavir (ATV/RTV) and an Oral Contraceptive in Healthy Females
Non-randomizedParallel-groupOpen-label
Summary
The purpose of this study is to administer a combined oral contraceptive (ethinyl estradiol and norgestimate) with the HIV treatment of atazanavir and ritonavir to healthy females in order to assess if the concentrations of the oral contraceptive change. The safety of this treatment regimen will also be studied.
Timeline
- Start
- 2006-07
- Primary completion
- 2006-11
- Completion
- 2006-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atazanavir | Other / unclassified | 300 mg | Oral |
| Comparator | Norgestimate | Small molecule | 0.18 mg | Oral |
| Comparator | Norgestimate | Small molecule | 0.215 mg | Oral |
| Comparator | Norgestimate | Small molecule | 0.25 mg | Oral |
| Subject | Ritonavir | Other / unclassified | 100 mg | Oral |
| Comparator | ethinyl estradiol | Small molecule | 25 ug | Oral |
| Comparator | ethinyl estradiol | Small molecule | 35 ug | Oral |