Early Use of Hydrocortisone in Hypotensive Very Low Birth Weight Infants

Summary

The purpose of this study is to investigate the early use of hydrocortisone in hypotensive very low birth weight infants. Based on the observations that: * hypotension is a common problem in very low birthweight infants and is associated with brain injury and poor neurological outcomes; * some infants are refractory to standard treatment (volume expansion and vasopressors), which is not exempt of adverse effects; * relative adrenal insufficiency has been described in this population; we hypothesize that hydrocortisone is effective in the treatment of hypotension in this population and reduce the need for vasopressors.

Timeline

Start

2005-07

Primary completion

2010-05

Completion

2010-05

Drugs

Indications

No indication recorded.