drugset / Trial / NCT00364923

Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

NCT00364923

Phase 2 Completed 115 enrolled Acrotech Biopharma Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Primary • Determine the efficacy of pralatrexate with concurrent vitamin B12 and folic acid supplementation when administered to patients with relapsed or refractory peripheral T-cell lymphoma (PTCL) Secondary * Determine the safety of pralatrexate with concurrent vitamin B12 and folic acid supplementation when administered to patients with relapsed or refractory PTCL * Determine the pharmacokinetic (PK) profile of pralatrexate when administered with vitamin B12 and folic acid supplementation

Timeline

Start
2006-08
Primary completion
2009-01
Completion
2009-02-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Pralatrexate Other / unclassified 30 mg/m2 Intravenous