drugset / Trial / NCT00369785

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

NCT00369785

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

RATIONALE: Donepezil may help lessen confusion and fatigue and improve mood and quality of life in patients who have undergone radiation therapy for brain tumors. It is not yet known whether donepezil is more effective than a placebo in lessening side effects of radiation therapy in patients with brain tumors. PURPOSE: This randomized phase III trial is studying donepezil to see how well it works in lessening side effects of radiation therapy compared with a placebo in patients who have undergone radiation therapy for brain tumors.

Timeline

Start
2008-02
Primary completion
2012-07-01
Completion
2012-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Donepezil Small molecule 10 mg Oral