drugset / Trial / NCT00369785
Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors
Phase 3
Completed
198 enrolled
Wake Forest University Health Sciences
National Cancer Institute (NCI) · collab
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
RATIONALE: Donepezil may help lessen confusion and fatigue and improve mood and quality of life in patients who have undergone radiation therapy for brain tumors. It is not yet known whether donepezil is more effective than a placebo in lessening side effects of radiation therapy in patients with brain tumors. PURPOSE: This randomized phase III trial is studying donepezil to see how well it works in lessening side effects of radiation therapy compared with a placebo in patients who have undergone radiation therapy for brain tumors.
Timeline
- Start
- 2008-02
- Primary completion
- 2012-07-01
- Completion
- 2012-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Donepezil | Small molecule | 10 mg | Oral |