Study to Assess the Effect Of Alosetron On Mucosal Blood Flow

Summary

This study will look at colonic mucosal blood flow in subjects who have taken alosetron vs placebo and healthy volunteers vs diarrhea-predominant Irritable Bowel Syndrome (d-IBS) patients.

Timeline

Start

2006-12

Primary completion

2007-12

Completion

2007-12

Outcome

Missed primary endpoint

registry d-IBS Placebo vs d-IBS Alosetron; p = 0.131; Mean Difference (Final Values) -8.1 (95% CI -18.4 to 2.157) NCT00370032 ↗

registry Healthy Volunteers Placebo vs Healthy Volunteers Alosetron; p = 0.131; Mean Difference (Final Values) -9.11 (95% CI -21.2 to 2.997) NCT00370032 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Alosetron	Small molecule	—	—

Indications