Combination Chemotherapy for the Treatment of Indian Kala-Azar

Summary

The investigators are using a sequential design to combine miltefosine and AmBisome in different doses.

Timeline

Start

2006-09

Primary completion

—

Completion

—

Publications

• Sundar S, Rai M, Chakravarty J, Agarwal D, Agrawal N, Vaillant M, Olliaro P, Murray HW. New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine. Clin Infect Dis. 2008 Oct 15;47(8):1000-6. doi: 10.1086/591972.

Drugs

Indications