drugset / Trial / NCT00380146
Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women
Completed
31 enrolled
Professor Karen I Barnes
Global Fund · collabMedical Research Council, South Africa · collab
NaSingle-groupOpen-labelPrevention
Summary
The main purpose of this study is to compare the drug levels of sulfadoxine-pyrimethamine found when given to pregnant women for the prevention of malaria to those found in pregnant women given the same drug with artesunate for the treatment of malaria, and also with those drug levels found in non-pregnant women in other malaria treatment studies.
Timeline
- Start
- 2006-09
- Primary completion
- 2008-02
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | pyrimethamine | Small molecule | 1.25 mg/kg | — |
| Subject | sulfadoxine | Small molecule | 25 mg/kg | — |