drugset / Trial / NCT00381953
High-dose IFN and PEG IFN for Induction Therapy in Difficult to Treat Genotype 1 Patients With Chronic HCV
RandomizedParallel-groupOpen-labelTreatment
Summary
Comparison of virological breakthrough/relapse rate after dose adjustments and sustained virological response rate will be assessed by the type of induction.
Timeline
- Start
- 2003-02
- Primary completion
- 2006-04
- Completion
- 2006-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Peginterferon alfa-2a | Protein / enzyme biologic | 180 ug | — |
| Comparator | Peginterferon alfa-2a | Protein / enzyme biologic | 360 ug | — |
| Comparator | interferon alfa | Protein / enzyme biologic | 4.5 iu | — |
| Comparator | interferon alfa | Protein / enzyme biologic | 9 iu | — |
| Comparator | Ribavirin | Small molecule | — | — |